[1]AL-HARTHY N,KUMAGI T,COLTESCU C,et al.The specificity of fatigue in primary biliary cirrhosis:evaluation of a large clinic practice[J].Hepatology,2010,52(2):562-570.
|
[2]GU EL,YAO GB.The clinical characteristics of primary biliary cirrhosis in China:a systimatic review[J].Chin J Hepatol,2009,17(11):861-866.(in Chinese)顾而立,姚光弼.中国人原发性胆汁性肝硬化的临床特点:52年文献的系统分析[J].中华肝脏病杂志,2009,17(11):861-866.
|
[3]CAUCH-DUDEK K,ABBEY S,STEWART DE,et al.Fatigue in primary biliary cirrhosis[J].Gut,1998,43(5):705-710.
|
[4]HUET PM,DESLAURIERS J,TRAN A,et al.Impact of fatigue on the quality of life of patients with primary biliary cirrhosis[J].Am J Gastroenterol,2000,95(3):760-767.
|
[5]MELLS GF,PELLS G,NEWTON JL,et al.Impact of primary biliary cirrhosis on perceived quality of life:the UK-PBC national study[J].Hepatology,2013,58(1):273-283.
|
[6]QUARNETI C,MURATORI P,LALANNE C,et al.Fatigue and pruritus at onset identify a more aggressive subset of primary biliary cirrhosis[J].Liver Int,2015,35(2):636-641.
|
[7]JONES DE,AL-RIFAI A,FRITH J,et al.The independent effects of fatigue and UDCA therapy on mortality in primary biliary cirrhosis:results of a 9 year follow-up[J].J Hepatol,2010,53(5):911-917.
|
[8]BJORNSSON E,KALAITZAKIS E,NEUHAUSER M,et al.Fatigue measurements in patients with primary biliary cirrhosis and the risk of mortality during follow-up[J].Liver Int,2010,30(2):251-258.
|
[9]FORTON DM,PATEL N,PRINCE M,et al.Fatigue and primary biliary cirrhosis:association of globus pallidus magnetisation transfer ratio measurements with fatigue severity and blood manganese levels[J].Gut,2004,53(4):587-592.
|
[10]HOLLINGSWORTH K,JONES DE,EL-SHARKAWY A,et al.Autonomic dysfunction in primary biliary cirrhosis is associated with structural brain abnormalities,particularly in the globus pal idus[J].Hepatology,2007,46(Suppl 4):546a-547a.
|
[11]McD ONALD C,NEWTON J,LAI HM,et al.Central nervous system dysfunction in primary biliary cirrhosis and its relationship to symptoms[J].J Hepatol,2010,53(6):1095-1100.
|
[12]Mc DONALD C,BAKER S,LAI M,et al.Central cerebral activation is reduced in primary biliary cirrhosis and associated with excessive daytime sleepiness[J].Hepatology,2007,46(Suppl 4):546a.
|
[13]MONTAGNESE S,NSEMI LM,CAZZAGON N,et al.SleepWake profiles in patients with primary biliary cirrhosis[J].Liver Int,2013,33(2):203-209.
|
[14]NEWTON JL,GIBSON GJ,TOMLINSON M,et al.Fatigue in primary biliary cirrhosis is associated with excessive daytime somnolence[J].Hepatology,2006,44(1):91-98.
|
[15]BLACKBURN P,FREESTON M,BAKER CR,et al.The role of psychological factors in the fatigue of primary biliary cirrhosis[J].Liver Int,2007,27(5):654-661.
|
[16]JONES DE.Fatigue in cholestatic liver disease:is it all in the mind?[J].J Hepatol,2007,46(6):992-994.
|
[17]van OS E,van DEN BROEK WW,MULDER PG,et al.Depression in patients with primary biliary cirrhosis and primary sclerosing cholangitis[J].J Hepatol,2007,46(6):1099-1103.
|
[18]TALWALKAR JA,DONLINGER JJ,GOSSARD AA,et al.Fluoxetine for the treatment of fatigue in primary biliary cirrhosis:a randomized,double-blind control ed trial[J].Dig Dis Sci,2006,51(11):1985-1991.
|
[19]FRITH J,NEWTON JL.Autonomic dysfunction in chronic liver disease[J].Hepat Med,2011,3:81-87.
|
[20]PRICE JK,ESCHEIK C,WEINSTEIN AA,et al.Medications affecting the autonomic nervous system(ANS)do not explain abnormal diastolic blood pressure in patients with chronic hepatitis C(Ch-C)or non-alcoholic fatty liver disease(NAFLD)[J].Gastroenterology,2013,1441(5):s969.
|
[21]DYSON JK,ELSHARKAWY AM,LAMB CA,et al.Fatigue in primary sclerosing cholangitis is associated with sympathetic over-activity and increased cardiac output[J].Liver Int,2015,35(5):1633-1641.
|
[22]CARBONE M,MELLS GF,PELLS G,et al.Sex and age are determinants of the clinical phenotype of primary biliary cirrhosis and response to ursodeoxycholic acid[J].Gastroenterology,2013,144(3):560-569,e13-e14.
|
[23]NEWTON JL,HUDSON M,TACHTATZIS P,et al.Population prevalence and symptom associations of autonomic dysfunction in primary biliary cirrhosis[J].Hepatology,2007,45(6):1496-1505.
|
[24]NEWTON JL,DAVIDSON A,KERR S,et al.Autonomic dysfunction in primary biliary cirrhosis correlates with fatigue severity[J].Eur J Gastroenterol Hepatol,2007,19(2):125-132.
|
[25]HOLLINGSWORTH KG,NEWTON JL,TAYLOR R,et al.Pilot study of peripheral muscle function in primary biliary cirrhosis:potential implications for fatigue pathogenesis[J].Clin Gastroenterol Hepatol,2008,6(9):1041-1048.
|
[26]HOLLINGSWORTH KG,MACGOWAN GA,MORRIS L,et al.Cardiac torsion-strain relationships in fatigued primary biliary cirrhosis patients show accelerated aging:a pilot cross-sectional study[J].J Appl Physiol(1985),2012,112(12):2043-2048.
|
[27]EKERFORS U,SUNNERHAGEN KS,WESTIN J,et al.Muscle performance and fatigue in non-advanced chronic liver disease[J].Gastroenterology,2015,1481(4):s991.
|
[28]RUDIC JS,POROPAT G,KRSTIC MN,et al.Ursodeoxycholic acid for primary biliary cirrhosis[J].Cochrane Database Syst Rev,2012,12:CD000551.
|
[29]WANG X,WANG JB.The diagnosis and treatment of primary biliary citthosis[J].J Clin Hepatol,2015,31(10):1605-1607.(in Chinese)王眭,王江滨.原发性胆汁性肝硬化的诊断与治疗[J].临床肝胆病杂志,2015,31(10):1605-1607.
|
[30]KAPLAN MM,BONIS PA.Modafinil for the treatment of fatigue in primary biliary cirrhosis[J].Ann Intern Med,2005,143(7):546-547.
|
[31]JONES DE,NEWTON JL.An open study of modafinil for the treatment of daytime somnolence and fatigue in primary biliary cirrhosis[J].Aliment Pharmacol Ther,2007,25(4):471-476.
|
[32]IAN GS,de JONGH M,KAPLAN MM.Modafinil in the treatment of debilitating fatigue in primary biliary cirrhosis:a clinical experience[J].Dig Dis Sci,2009,54(10):2242-2246.
|
[33]SILVEIRA MG,GOSSARD AA,STAHLER AC,et al.A randomized,placebo-controlled clinical trial of efficacy and safety:modafinil in the treatment of fatigue in patients with primary biliary cirrhosis[J].Am J Ther,2016.[Epub ahead of print]
|
[34]TAN YG,YAN HP,GAO ZH.Research progress in role of B cell immunity in primary biliary cirrhosis[J].J Clin Hepatol,2014,30(5):400-404.(in Chinese)谭延国,闫惠平,高祖华.原发性胆汁性肝硬化中B细胞免疫的研究进展[J].临床肝胆病杂志,2014,30(5):400-404.
|
[35]MYERS RP,SWAIN MG,LEE SS,et al.B-cell depletion with rituximab in patients with primary biliary cirrhosis refractory to ursodeoxycholic acid[J].Am J Gastroenterol,2013,108(6):933-941.
|
[36]JOPSON L,NEWTON JL,PALMER J,et al.RITPBC:Bcell depleting therapy(rituximab)as a treatment for fatigue in primary biliary cirrhosis:study protocol for a randomised controlled trial[J].BMJ Open,2015,5(8):e7985.
|
[37]CARBONE M,BUFTON S,MONACO A,et al.The effect of liver transplantation on fatigue in patients with primary biliary cirrhosis:a prospective study[J].J Hepatol,2013,59(3):490-494.
|
[38]PELLS G,MELLS GF,CARBONE M,et al.The impact of liver transplantation on the phenotype of primary biliary cirrhosis patients in the UK-PBC cohort[J].J Hepatol,2013,59(1):67-73.
|