中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

2016 No. 11

Display Method:
Editorial
Antiviral therapy for chronic hepatitis B: current status and perspectives
Fan Rong, Sun Jian, Hou JinLin
2016, 32(11): 2029-2032. DOI: 10.3969/j.issn.1001-5256.2016.11.001
Abstract:

Chronic hepatitis B is an important public health issue in China. The drugs used as the antiviral therapy for hepatitis B are mainly interferons and nucleos( t) ide analogues. Although these drugs have realized persistent HBV inhibition in most patients,a large number of patients cannot achieve immu...

Therapeutic guidelines
An excerpt of guideline for the evaluation of cholestatic jaundice in infants: joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) in 2016
Ma LinJie, Chen Gang, Hu ZongQiang
2016, 32(11): 2033-2035. DOI: 10.3969/j.issn.1001-5256.2016.11.002
Abstract:
An excerpt of non-alcoholic fatty liver disease (NAFLD): assessment and management (NICE guidelines in 2016) 
Liu Tao, Zhang Li, Fan JianGao, Ji Guang
2016, 32(11): 2036-2038. DOI: 10.3969/j.issn.1001-5256.2016.11.003
Abstract:
Discussions by experts
Diagnosis and treatment of hepatitis B virus infection complicated by metabolic syndrome
Liu Jing, Shi JunPing
2016, 32(11): 2039-2042. DOI: 10.3969/j.issn.1001-5256.2016.11.004
Abstract:

With the prevalence of obesity around the world,the incidence rate of hepatitis B virus( HBV) infection complicated by metabolic syndrome( MS) is increasing year by year,and such patients have become a special population in patients with chronic HBV infection. In recent years,the research on the fea...

Advances in research and development of new drugs for antiviral therapy for chronic hepatitis B
Gao YanHang, Liu PeiYan, Gao PuJun
2016, 32(11): 2043-2049. DOI: 10.3969/j.issn.1001-5256.2016.11.005
Abstract:

Chronic hepatitis B virus( HBV) infection is one of the major disease burdens worldwide. At present,the antiviral therapy for hepatitis B includes interferons and nucleos( t) ide analogues. Current therapeutic regimens based on these drugs cannot significantly increase the proportion of patients wit...

How to evaluate combination therapy using interferon and nucleos(t)ide analogues
Chen Lu, Xie Qing
2016, 32(11): 2050-2053. DOI: 10.3969/j.issn.1001-5256.2016.11.006
Abstract:

Chronic hepatitis B is still one of the most important chronic diseases in China because of its high relevance to liver cirrhosis and hepatic cell cancer( HCC). Currently,interferon and nucleos( t) ide analogues are two main treatments for chronic hepatitis B,but they have advantages and disadvantag...

New considerations in antiviral therapy for special populations with chronic hepatitis B
Hu XiaoYun, Sun Jian, Peng Jie
2016, 32(11): 2054-2057. DOI: 10.3969/j.issn.1001-5256.2016.11.007
Abstract:

Increasing attentions have been paid to the antiviral therapy for special populations with chronic hepatitis B( CHB),including patients co- infected with HIV,HDV,or HCV,children and adolescents,pregnant women,patients with chronic kidney diseases,and patients who require chemotherapy or immunosuppre...

Role of liver fibrosis assessment in decision-making and efficacy surveillance for antiviral therapy in patients with chronic hepatitis B
Liang XieEr, Chen YongPeng
2016, 32(11): 2058-2061. DOI: 10.3969/j.issn.1001-5256.2016.11.008
Abstract:

Liver fibrosis / cirrhosis is the outcome of the progression of chronic hepatitis B and is associated with liver events and long- term prognosis. Effective antiviral therapy can delay or even reverse disease progression. Therefore,assessment of liver fibrosis degree before and during treatment is of...

Research advances in primary biliary cholangitis
Duan WeiJia, Tian QiuJu, You Hong, Jia JiDong
2016, 32(11): 2062-2065. DOI: 10.3969/j.issn.1001-5256.2016.11.009
Abstract:

Primary biliary cholangitis is a chronic intrahepatic cholestatic liver disease and has increasing incidence and prevalence rates,as is reported in the literature. Examination of specific antibodies including serum anti- mitochondrial antibody subtype M2 and liver histopathological examination help ...

Original articles_Viral hepatitis
Clinical effect of 24-week TDF versus ADV sequential therapy in HBeAg-positive chronic hepatitis B patients with suboptimal response to 48-week pegylated interferon-α-2a treatment
Lu: Ying, Chen XiaoRong
2016, 32(11): 2066-2069. DOI: 10.3969/j.issn.1001-5256.2016.11.010
Abstract:

Objective To investigate the clinical effect of 24- week tenofovir disoproxil fumarate( TDF) sequential therapy in HBeAg- positive chronic hepatitis B( CHB) patients with suboptimal serological response to 48- week pegylated interferon- α- 2a( Peg- IFN- α- 2a) monotherapy. Methods A total of 21 pati...

Clinical effect of entecavir combined with thymosin in treatment of HBe Ag-positive hepatitis B patients
Huang Ling, Ning HuiMing, Xu YanHua, Tang Qun, Ou Qiang
2016, 32(11): 2070-2074. DOI: 10.3969/j.issn.1001-5256.2016.11.011
Abstract:

Objective To investigate the clinical effect of entecavir( ETV) combined with thymosin in the treatment of HBe Ag- positive chronic hepatitis B( CHB) patients. Methods A total of 108 HBe Ag- positive CHB patients who were treated in Department of Infectious Diseases in our hospital from March 2012 t...

An analysis of medication rule for HBeAg-positive chronic hepatitis B based on association rule and complex system entropy clustering
Jiao YunTao, Li XiaoKe, Yang XianZhao, Ye YongAn
2016, 32(11): 2075-2079. DOI: 10.3969/j.issn.1001-5256.2016.11.012
Abstract:
Objective To investigate the features of traditional Chinese medicine( TCM) and prescription rules in the treatment of HBeAg- positive chronic hepatitis B( CHB). Methods A systematic search was performed for the articles on the TCM diagnosis and treatment of HBeAg-positive CHB,the information of TCM...
Impact of nucleos(t)ide analogues on quality of life in patients with chronic hepatitis B
Zhong ChunXiu, Cai ShaoHang, Yin JunHua, Gao YuLin
2016, 32(11): 2080-2083. DOI: 10.3969/j.issn.1001-5256.2016.11.013
Abstract:

Objective To investigate the impact of treatment with nucleos( t) ide analogues on quality of life( Qo L) in patients with chronic hepatitis B( CHB),as well as proper nursing measures. Methods A total of 102 CHB patients who were treated in Department of Infectious Diseases,Nanfang Hospital,Southern...

Clinical effect of entecavir in treatment of patients with chronic hepatitis B complicated by tuberculosis
Zhu DongLiang, Li DaoBo, Zhao ManZhi, Ma Ke, Song JianXin, Xu Dong
2016, 32(11): 2084-2087. DOI: 10.3969/j.issn.1001-5256.2016.11.014
Abstract:

Objective To investigate the clinical effect of entecavir in the treatment of patients with chronic hepatitis B( CHB) complicated by tuberculosis during anti- tuberculosis treatment. Methods A retrospective study was performed for the clinical data of 95 patients with CHB complicated by tuberculosis...

Clinical effect of entecavir combined with antituberculosis therapy in patients with tuberculosis complicated by chronic HBV infection
Hong YouZhi, Huang JiShui, Hong WenCong, Jiang TaoYuan
2016, 32(11): 2088-2091. DOI: 10.3969/j.issn.1001-5256.2016.11.015
Abstract:

Objective To investigate the clinical effect of entecavir combined with antituberculosis therapy in patients with tuberculosis complicated by chronic HBV infection. Methods A total of 108 patients with tuberculosis complicated by chronic HBV infection were divided into entecavir group with 58 patien...

An investigation of clinical features of HBsAg and anti-HBs positive patients with chronic hepatitis B
Song JinYun, Wang JianFang, Wu XuPing, Huang Ling
2016, 32(11): 2092-2095. DOI: 10.3969/j.issn.1001-5256.2016.11.016
Abstract:
Objective To investigate the phenomenon of coexistence of HBsAg and anti- HBs and its clinical features,as well as related causes. Methods A total of 2260 persons who underwent physical examination in The Second Affiliated Hospital of Southeast University from February 2011 to February 2014 were enr...
Clinical features of patients with acute exacerbation of chronic hepatitis B: an analysis of 74 cases
Ruan JianWen, Gao LiJuan, Su RuKai
2016, 32(11): 2096-2098. DOI: 10.3969/j.issn.1001-5256.2016.11.017
Abstract:
Objective To investigate the clinical features of patients with acute exacerbation of chronic hepatitis B,and to provide a basis of evidence- based medicine for the diagnosis and treatment of acute exacerbation of chronic hepatitis B. Methods A retrospective analysis was performed for the clinical d...
Correlation between HBsAg,prothrombin time activity,and indocyanine green retention rate at 15 minutes in patients with HBeAg-positive chronic HBV infection
Fan WenHai, Zhao ZhengBin, Chen QingFeng, Zhang LiTing, Wang FeiFei, Wang Qiong, Wang Shan, Wei Xin
2016, 32(11): 2099-2102. DOI: 10.3969/j.issn.1001-5256.2016.11.018
Abstract:
Objective To investigate the correlation between HBsAg,prothrombin time activity( PTA),and indocyanine green retention rate at 15 minutes( ICG R15) in patients with HBeAg- positive chronic HBV infection. Methods A total of 92 patients with HBeAg- positive chronic HBV infection who were admitted to T...
HBV genotyping of 702 hepatitis B patients in Changchun,China and its clinical significance
Yuan Ye, Yu XueJiao, Lu NianHong, Zhang MingWei
2016, 32(11): 2103-2106. DOI: 10.3969/j.issn.1001-5256.2016.11.019
Abstract:
Objective To investigate the distribution of HBV genotypes in Changchun,China,as well as the association of genotypes with virus replication level,serum markers,and liver impairment and its clinical significance. Methods A total of 702 patients with HBV infection who visited The First Hospital of Ji...
Effect of hepatitis B virus rtA181T mutation on autophagy of Huh7 hepatoma cells
Shi JingRen, Guo XiangHua, Wang JieLin, Wang ShanShan, Qiao LuXin, Chen DeXi
2016, 32(11): 2107-2111. DOI: 10.3969/j.issn.1001-5256.2016.11.020
Abstract:
Objective To investigate the effect of reverse transcriptase A181T( rtA181T) mutation in hepatitis B virus( HBV) on autophagy of Huh7 hepatoma cells. Methods Huh7 hepatoma cells were transfected with wild- type( WT) 1. 3mer HBV plasmids( WT group),1. 3mer HBV rt A181 T mutant plasmids( 181 T group),...
Original articles_Liver fibrosis and liver cirrhosis
Effect of transjugular intrahepatic portosystemic shunt combined with splenic artery embolization on hepatic hemodynamics and liver function in patients with liver cirrhosis
Liang XiaoHua, Zhang Feng, Zhu GeYuZheng
2016, 32(11): 2112-2117. DOI: 10.3969/j.issn.1001-5256.2016.11.021
Abstract:
Objective To investigate the effect of transjugular intrahepatic portosystemic shunt( TIPS) combined with splenic artery embolization( SAE) on hepatic hemodynamics,liver function,and prognosis in patients with liver cirrhosis. Methods A total of 24 patients who underwent TIPS in the Department of Ga...
Value of serum cancer antigen12-5 level in diagnosis of peritoneal effusion in patients with liver cirrhosis
Zhang Hui, Jia Lei, Lu: Dong, Xu YouQing
2016, 32(11): 2118-2120. DOI: 10.3969/j.issn.1001-5256.2016.11.022
Abstract:
Objective To investigate the value of serum cancer antigen 12- 5( CA12- 5) level in the diagnosis of peritoneal effusion in patients with liver cirrhosis. Methods A total of 142 patients with liver cirrhosis who were hospitalized at Beijing Tiantan hospital from January 2011 to December 2015 and met...
Original articles_Liver neoplasms
Clinical effect of liver cancer resection combined with selective decongestive devascularization in treatment of primary liver cancer complicated by portal hypertension
Zheng GuiLong, Ding HaiHua, Ding ZhiQing, Deng XianRen, Xia JingBo, Li HongXin
2016, 32(11): 2121-2125. DOI: 10.3969/j.issn.1001-5256.2016.11.023
Abstract:
Objective To investigate the clinical effect of liver cancer resection combined with selective decongestive devascularization in the treatment of primary liver cancer complicated by portal hypertension. Methods A retrospective analysis was performed for the clinical data of 60 patients with primary ...
Influence of Forkhead box Q1 expression on therapeutic effect of transarterial chemoembolization after hepatocellular carcinoma surgery
Zhou YiLong, Chen Yuan, Zhang YiXin, Shao BingFeng, Zhang SuQing, Xu AiBing, He Song, Li YongJun, Tian SiYuan
2016, 32(11): 2126-2129. DOI: 10.3969/j.issn.1001-5256.2016.11.024
Abstract:
Objective To investigate the expression of Forkhead box Q1( FOXQ1) in the tissue of hepatocellular carcinoma( HCC),its influence on the prognosis of surgical resection combined with transarterial chemoembolization( TACE),and the value of FOXQ1 in evaluating the treatment outcome of HCC. Methods A to...
Original articles_Biliary diseases
Role of reproductive factors in female patients with primary biliary cholangitis
Chen Jing, Guo ZhangCun, Shi YongQuan, Zhou XinMin, He XiaoXia, Chen Yu, Wang Lu, Guo GuanYa, Han ZheYi, Han Ying
2016, 32(11): 2130-2133. DOI: 10.3969/j.issn.1001-5256.2016.11.025
Abstract:
Objective To investigate the role of productive factors in the development of primary biliary cholangitis( PBC). Methods A total of 273 female patients with a definite diagnosis of PBC who visited Xijing Hospital from October 2013 to August 2015 were enrolled. The patients with autoimmune hepatitis,...
Diagnosis of clonorchiasis during and after biliary tract surgery: a clinical analysis of 15 cases
Qi WenLei, Zhang RuoYan, Chai WenGang, Liu MingJiang, Du XiaoHong, Ye JunFeng
2016, 32(11): 2134-2137. DOI: 10.3969/j.issn.1001-5256.2016.11.026
Abstract:
Objective To investigate the clinical features of clonorchiasis diagnosed during biliary surgery,and to provide more comprehensive and effective information for the surgical treatment of clonorchiasis. Methods A retrospective analysis was performed for the clinical data of 15 patients who were diagn...
Value of cold laser combined with choledochoscopy in treatment of residual stones after biliary surgery
Jiang ZheLong, Pan Fan, Lu: LiZhi, Jiang Yi
2016, 32(11): 2138-2140. DOI: 10.3969/j.issn.1001-5256.2016.11.027
Abstract:
Objective To investigate the value of cold laser combined with choledochoscopy in the treatment of residual stones after biliary surgery. Methods A retrospective analysis was performed for the clinical data of 79 patients with residual stones after biliary surgery who were admitted to Fuzhou General...
Application of fast track surgery strategy in perioperative period of primary suture of laparoscopic choledocholithotomy
Liu JinHeng, Wang YanTing, Yi Bin, Gao Yuan, Chen AnPing, Zhang ShengLong
2016, 32(11): 2141-2145. DOI: 10.3969/j.issn.1001-5256.2016.11.028
Abstract:
Objective To investigate the clinical application value of fast track surgery strategy( EARS) in the perioperative period of primary suture of laparoscopy in the treatment of common bile duct stones. Methods A total of 64 patients with gallstones complicated by common bile duct stones who were hospi...
Original articles_Pancreatic diseases
Effect of angiotensin 1-7 on the TLR4/NF-κB pathway in cerulein-induced pancreatic acinar cells
Wang Yan, Cui LiJian, Xiao HongLi, Wang GuoXing, Yin ChengHong
2016, 32(11): 2146-2150. DOI: 10.3969/j.issn.1001-5256.2016.11.029
Abstract:
Objective To investigate the effect of angiotensin 1- 7 [Ang( 1- 7) ] on the TLR4 / NF- κB pathway in cerulein- stimulated pancreatic acinar AR42 J cells. Methods AR42 J cells were randomly divided into control group,model group( stimulated with 10 nmol / L cerulein),Ang( 1- 7) group( 10- 7,10- 6,an...
Original articles_Others
Clinical effect of alprostadil combined with entecavir in treatment of HBV-related liver failure complicated by ascites
Ji HuiChun, Zhang ZhenJiang, Zhu Fang, Liu JunQuan, Liu QingDe, Pang Wei
2016, 32(11): 2151-2154. DOI: 10.3969/j.issn.1001-5256.2016.11.030
Abstract:

Objective To investigate the clinical effect of alprostadil combined with entecavir in the treatment of HBV- related liver failure complicated by ascites. Methods A total of 84 patients with HBV- related liver failure complicated by ascites who were hospitalized and treated in No. 97 Hospital of PLA...

Clinical value of indocyanine green retention rate in condition analysis and prognostic evaluation of patients with HBV-related acute-on-chronic liver failure
Liu JingHua, Liu Na, Liu ChenXi
2016, 32(11): 2155-2158. DOI: 10.3969/j.issn.1001-5256.2016.11.031
Abstract:

Objective To investigate the clinical value of indocyanine green retention rate at 15 min( ICG R15) in the condition analysis and prognostic evaluation of patients with acute- on- chronic liver failure( ACLF),and to provide a reference index for condition analysis and prognostic evaluation of patien...

Guiding significance of Guideline for diagnosis and treatment of herb-induced liver injury in clinical diagnosis: a retrospective analysis
Zhu Yun, Wang RuiLin, Sun XueYing, Yu SiMiao, Jing Jing, Wang JiaBo, He TingTing, Huang YiXue, Wang LiPing, Sun YongQiang
2016, 32(11): 2159-2162. DOI: 10.3969/j.issn.1001-5256.2016.11.032
Abstract:

Objective To investigate the clinical guiding significance of Guideline for diagnosis and treatment of herb- induced liver injury in the diagnosis of herb- induced liver injury( HILI). Methods A retrospective analysis was performed for the clinical data of 595 hospitalized patients who were admitted...

Clinical effect of matrine in treatment of rats with nonalcoholic steatohepatitis
Ai ZhengLin, Xie BuShan, Yao ShuKun
2016, 32(11): 2163-2166. DOI: 10.3969/j.issn.1001-5256.2016.11.033
Abstract:

Objective To investigate the antioxidant effect of matrine and its clinical effect in the treatment of rats with nonalcoholic steatohepatitis( NASH). Methods A total of 30 rats were randomly divided into three groups: control group,NASH group,and matrine group,with 10 in each. A high- fat diet was u...

Case reports
Thrombotic cavernous transformation of the portal vein secondary to hepatitis B cirrhosis treated with warfarin: a case report
Yuan Wei, Zhang YuYi, Zhang ZhengGuo, Zou Ying, Wang JieFei, Qian ZhiPing
2016, 32(11): 2167-2168. DOI: 10.3969/j.issn.1001-5256.2016.11.034
Abstract:
A case of giant hepatoblastoma
Ma LinJie, Chen Xiao, Zou Long, Liu Hong, Hu ZongQiang, Bai JianHua, Chen Gang
2016, 32(11): 2169-2170. DOI: 10.3969/j.issn.1001-5256.2016.11.035
Abstract:
A case of ectopic pancreas in the gastric antrum misdiagnosed as hepatic cyst
Hao Qiao, Xue JianFeng, Tian XiangYong, Hu JunLong
2016, 32(11): 2171-2172. DOI: 10.3969/j.issn.1001-5256.2016.11.036
Abstract:
A case of hepatolenticular degeneration with mental disorder as initial symptomc
Cui YuanYuan, Yang YiLiang, Wang ShaSha, Hua Rui
2016, 32(11): 2173-2174. DOI: 10.3969/j.issn.1001-5256.2016.11.037
Abstract:
A case of hepatic alveolar echinococcosis
Wang ZhiWei, Li Qiang, Chai Chen
2016, 32(11): 2175-2176. DOI: 10.3969/j.issn.1001-5256.2016.11.038
Abstract:
A case of gallstones with gallbladder-stomach fistula and biliary ileus
Lin QianHuang, Xu Hui, Tang XiaoLong, Ding Zheng, Tang WenJun, Wu KaiKai, Xun JinLiang
2016, 32(11): 2177-2178. DOI: 10.3969/j.issn.1001-5256.2016.11.039
Abstract:
Infarct of spleen infarction after laparoscopic spleen-preserving distal pancreatectomy conservation of the splenic arteries and veins: a case  report
Zhao Lei, Zhang Ping, Shi XiaoJu, Zang MingCui, Wei Feng, Wang GuangYi
2016, 32(11): 2179-2181. DOI: 10.3969/j.issn.1001-5256.2016.11.040
Abstract:
Reviews
Research advances in tenofovir in treatment of chronic hepatitis B patients with drug resistance
Yan YueRong, Feng JiHong
2016, 32(11): 2182-2185. DOI: 10.3969/j.issn.1001-5256.2016.11.041
Abstract:
Currently,tenofovir is the first- line drug for the treatment of chronic hepatitis B. This article reviews the research advances in its therapeutic effects in patients who are resistant to lamivudine and adefovir dipivoxil,respond poorly to entecavir,or have multidrug resistance and introduces the r...
Influence of interaction between endogenous miRNAs and hepatitis B virus in hepatocytes on hepatitis B virus transcription and related mechanisms
Qiu Hua, Sun XueHua, Zhou ZhenHua, Li Man, Zhang Xin, Gao YueQiu
2016, 32(11): 2186-2190. DOI: 10.3969/j.issn.1001-5256.2016.11.042
Abstract:
MicroRNAs( miRNAs) may be involved in the regulation of gene expression after transcription and play important roles in regulating hepatitis B virus( HBV) transcription and replication. This article summarizes the miRNAs with an anti- HBV effect in hepatocytes and4 regulatory mechanisms,as well as t...
Mechanisms of hyponatremia in patients with decompensated liver cirrhosis treated with terlipressin and related treatment principles
You Jia, Jiang JiaJi
2016, 32(11): 2191-2194. DOI: 10.3969/j.issn.1001-5256.2016.11.043
Abstract:
Esophagogastric variceal bleeding and hepatorenal syndrome are common complications in patients with decompensated liver cirrhosis and portal hypertension. Terlipressin can lead to the constriction of visceral vessels,reduce portal venous pressure,and increase renal perfusion and is the first- line ...
Regulatory effect of transforming growth factor-β on activation of hepatic stellate cells
Zhao WeiHua, Wang YanHong, Cong Min
2016, 32(11): 2195-2198. DOI: 10.3969/j.issn.1001-5256.2016.11.044
Abstract:
In the process of liver fibrosis,transforming growth factor β( TGFβ) is considered an important regulatory factor for the activation of hepatic stellate cells( HSCs) and extracellular matrix production. Therefore,the therapeutic strategies targeted at the activation of HSCs and liver fibrosis induce...
Prevention of surgical site infection after liver cancer resection
Xu Feng, Tang Bin, Dai ChaoLiu, Wang Chao, Liu XiaoLin
2016, 32(11): 2199-2202. DOI: 10.3969/j.issn.1001-5256.2016.11.045
Abstract:
Surgical site infection( SSI) often increases the length of hospital stay,economic burden,and even mortality of patients undergoing liver cancer resection. Targeted preventive measures help to reduce SSI. This article introduces the preventive measures for SSI,including improvement of patients' phys...
Diagnostic value of H19 gene in hepatocellular carcinoma
Wang ShiMei, Wu Xia, Kang Peng, Meng QingYang
2016, 32(11): 2203-2205. DOI: 10.3969/j.issn.1001-5256.2016.11.046
Abstract:
Recent studies have shown that some long non- coding RNAs( lncRNAs) are expressed abnormally in hepatocellular carcinoma( HCC) tissue,and the expression of H19 gene in lncRNAs in HCC tissue is significantly higher than that in normal tissue. After the knockout of H19 gene,the proliferative and invas...
Expression and role of heat shock protein 70 in hepatocellular carcinoma
He ZeLing, Cao JianBiao, Fan GongRen
2016, 32(11): 2206-2209. DOI: 10.3969/j.issn.1001-5256.2016.11.047
Abstract:
Heat shock protein 70( HSP70) is expressed differently in hepatocellular carcinoma( HCC) tissues. Since its expression and regulatory mechanism remain unclear,whether HSP70 can help with the early diagnosis,treatment,and prognostic evaluation of HCC has become a hot research topic. This article revi...
Value of ultrasonic elastography in diagnosis of liver diseases
Zhang XiaoTong, Guo LiPing
2016, 32(11): 2210-2213. DOI: 10.3969/j.issn.1001-5256.2016.11.048
Abstract:
Ultrasonic elastography is a new technique of ultrasonic diagnosis and plays an important role in the diagnosis and monitoring of chronic liver diseases in recent years. This article introduces the principle and classification of ultrasonic elastography,as well as the application value of different ...
Research advances in diagnosis and treatment of liver disease during pregnancy
Luo Huan, Huang WenXiang
2016, 32(11): 2214-2217. DOI: 10.3969/j.issn.1001-5256.2016.11.049
Abstract:
Liver disease during pregnancy is classified as pregnancy- specific liver disease and non- pregnancy- specific liver disease. The unique physicochemical status during pregnancy increases the burden of liver metabolism. Once liver injury occurs,it tends to be more serious and is closely associated wi...
Research advances in pathogenesis and management of fatigue in patients with primary biliary cirrhosis
Zhao Jian, Cao Jia, Yao DingKang
2016, 32(11): 2218-2221. DOI: 10.3969/j.issn.1001-5256.2016.11.050
Abstract:
Fatigue is one of the most common symptoms of primary biliary cirrhosis( PBC) and greatly affects patients' quality of life. The pathogenesis of fatigue in PBC remains unknown and there are no effective therapeutic methods. This article reviews the latest advances in the pathogenesis and treatment o...
Role of chymotrypsin C in development and progression of pancreatitis and pancreatic cancer
Liu ZeJie, Song YiLin, Li Hong, Feng YingMing, Su HaiChuan
2016, 32(11): 2222-2225. DOI: 10.3969/j.issn.1001-5256.2016.11.051
Abstract:
Chymotrypsin C( CTRC) is a trypsinogen synthesized by pancreatic acinar cells and secreted by pancreatic duct cells and belongs to the family of serine chymotrypsin. The main function of CTRC is to regulate the balance between activation and degradation of trypsin and maintain the structural and fun...