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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 12
Dec.  2016
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Article Contents

Research advances in the application of specific molecular probes for positron emission tomography in diagnosis of early-stage liver fibrosis

DOI: 10.3969/j.issn.1001-5256.2016.12.009
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  • Published Date: 2016-12-20
  • Liver fibrosis is a symbolic process of many chronic liver diseases,and liver biopsy is the gold standard for the diagnosis of liver fibrosis in clinical practice. At present,there is a lack of effective methods for the noninvasive diagnosis of early- stage liver fibrosis. The process of liver fibrosis is accompanied by complicated changes at the molecular level,which are associated with the progression of liver fibrosis. As an imaging examination which can provide the information at the molecular level such as tissue function and metabolism,positron emission tomography( PET) has the ability to monitor such quantitative information. This article mainly introduces the principles of specific molecular probes for PET used in the diagnosis of early- stage liver fibrosis,summarizes the value of these specific molecular probes in the diagnosis and staging of early- stage liver fibrosis,and points out that it is necessary to find more specific molecular probes for the diagnosis of early- stage liver fibrosis.

     

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