|
[1]FATTOVICH G, BORTOLOTTI F, DONATO F.Natural history o chronic hepatitis B:special emphasis on disease progression and prognostic factors[J].J Hepatol, 2008, 48 (2) :335-352.
|
|
[2]TIAN Y, KUO CF, AKBARI O, et al.Maternal-derived hepatitis B virus e antigen alters macrophage function in offspring to drive viral persistence after vertical transmission[J].Immunity, 2016, 44 (5) :1204-1214.
|
|
[3]SINGH AE, PLITT SS, OSIOWY C, et al.Factors associated with vaccine failure and vertical transmission of hepatitis B among a cohort of Canadian mothers and infants[J].J Viral Hepat, 2011, 18 (7) :468-473.
|
|
[4]MILICH D, LIANG TJ.Exploring the biological basis of hepatitis Be antigen in hepatitis B virus infection[J].Hepatology, 2003, 38 (5) :1075-1086.
|
|
[5]KOUMBI L, BERTOLETTI A, ANASTASIADOU V, et al.Hepatitis B-specific T helper cell responses in uninfected infants born to HBs Ag+/HBe Ag-mothers[J].Cell Mol Immunol, 2010, 7 (6) :454-458.
|
|
[6]BERTOLETTI A, KENNEDY PT.The immune tolerant phase of chronic HBV infection:new perspectives on an old concept[J].Cell Mol Immunol, 2015, 12 (3) :258-263.
|
|
[7]HONG M, SANDALOVA E, LOW D, et al.Trained immunity in newborn infants of HBV-infected mothers[J].Nat Commun, 2015, 6:6588.
|
|
[8]BECKEBAUM S, CICINNATI VR, ZHANG X, et al.Hepatitis Bvirus-induced defect of monocyte-derived dendritic cells leads to impaired T helper type 1 response in vitro:mechanisms for viral immune escape[J].Immunology, 2003, 109 (4) :487-495.
|
|
[9]CHEN L, ZHANG Z, CHEN W, et al.B7-H1 up-regulation on myeloid dendritic cells significantly suppresses T cell immune function in patients with chronic hepatitis B[J].J Immunol, 2007, 178 (10) :6634-6641.
|
|
[10]LAN SS, WANG XY, WU LC, et al.Hepatitis B virus e antigen (HBe Ag) may have a negative effect on dendrtic cells maturation[J].Int J Clin Exp Pathol, 2016, 9 (2) :742-749.
|
|
[11]CHEN LM, FAN XG, MA J, et al.Molecular mechanisms of HBe Ag in persistent HBV infection[J].Hepatol Int, 2017, 11 (1) :79-86.
|
|
[12]SHI CC, TJWA ET, BIESTA PJ, et al.Hepatitis B virus suppresses the functional interaction between natural killer cells and plasmacytoid dendritic cells[J].J Viral Hepat, 2012, 19 (2) :e26-e33.
|
|
[13]CHISARI FV, ISOGAWA M, WIELAND SF.Pathogenesis of hepatitis B virus infection[J].Pathol Biol (Paris) , 2010, 58 (4) :258-266.
|
|
[14]LI M, SUN R, XU L, et al.Kupffer cells support hepatitis B virus-mediated CD8+T cell exhaustion via hepatitis B core antigenTLR2 interactions in mice[J].J Immunol, 2015, 195 (7) :3100-3109.
|
|
[15]LAN P, ZHANG C, HAN Q, et al.Therapeutic recovery of hepatitis B virus (HBV) -induced hepatocyte-intrinsic immune defect reverses systemic adaptive immune tolerance[J].Hepatology, 2013, 58 (1) :73-85.
|
|
[16]JIANG W.Blockade of B7-H1 enhances dendritic cell-mediated T cell response and antiviral immunity in HBV transgenic mice[J].Vaccine, 2012, 30 (4) :758-766.
|
|
[17]SCHURICH A, PALLETT LJ, JAJBHAY D, et al.Distinct metabolic requirements of exhausted and functional virus-specific CD8 T cells in the same host[J].Cell Reports, 2016, 16 (5) :1243-1252.
|
|
[18]MASON WS, GILL US, LITWIN S, et al.HBV DNA integration and clonal hepatocyte expansion in chronic hepatitis B patients considered immune tolerant[J].Gastroenterology, 2016, 151 (5) :986-998.
|
|
[19]KENNEDY PT, SANDALOVA E, JO J, et al.Preserved T-cell function in children and young adults with immune-tolerant chronic hepatitis B[J].Gastroenterology, 2012, 143 (3) :637-645.
|
|
[20]SETO WK, YUEN MF.Viral hepatitis:‘Immune tolerance’in HBV infection:danger lurks[J].Nat Rev Gastroenterol Hepatol, 2016, 13 (11) :627-628.
|
|
[21]LI X, TIAN L, DONG Y, et al.IL-35 inhibits HBV antigenspecific IFN-γ-producing CTLs in vitro[J].Clin Sci (Lond) , 2015, 129 (5) :395-404.
|
|
[22]ZHANG HW, YIN JH, LI YT, et al.Risk factors for acute hepatitis B and its progression to chronic hepatitis in Shanghai, China[J].Gut, 2008, 57 (12) :1713-1720.
|
|
[23]TONG S, REVILL P.Overview of hepatitis B viral replication and genetic variability[J].J Hepatol, 2016, 64 (1) :s4-s16.
|
|
[24]CHEN C, CHANGCHIEN CS, LEE CM, et al.Combined mutations in pre-S/surface and core promoter/precore regions of hepatitis B virus increase the risk of hepatocellular carcinoma:a casecontrol study[J].J Infect Dis, 2008, 198 (11) :1634-1642.
|
|
[25]LI JS, TONG SP, WEN YM, et al.Hepatitis B virus genotype Ararely circulates as an HBe-minus mutant:possible contribution o a single nucleotide in the precore region[J].J Virol, 1993, 67 (9) :5402-5410.
|
|
[26]YAN L, ZHANG H, MA H, et al.Deep sequencing of hepatitis Bvirus basal core promoter and precore mutants in HBe Ag-positive chronic hepatitis B patients[J].Sci Rep, 2015, 5:17950.
|
|
[27]SINGH R, KAUL R, KAUL A, et al.A comparative review o HLA associations with hepatitis B and C viral infections across global populations[J].World J Gastroenterol, 2007, 13 (12) :1770-1787.
|
|
[28]ZHU M, DAI J, WANG C, et al.Fine mapping the MHC region identified four independent variants modifying susceptibility to chronic hepatitis B in Han Chinese[J].Hum Mol Genet, 2016, 25 (6) :1225-32.
|
|
[29]CHANG SW, FANN CS, SU WH, et al.A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese[J].PLo S One, 2014, 9 (6) :e99724.
|
|
[30]ZHANG Y, ZHAO F, LAN L, et al.Correlation of HLA-DQB1 gene polymorphism of Xinjiang Uygur with outcome of HBV infection[J].Int J Clin Exp Med, 2015, 8 (4) :6067.
|
|
[31]AL-QAHTANI AA, AL-ANAZI MR, ABDO AA, et al.Association between HLA variations and chronic hepatitis B virus infection in Saudi Arabian patients[J].PLo S One, 2014, 9 (1) :e80445.
|
|
[32]NISHDA N, SAWAI H, KASHIWASE K, et al.New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia[J].PLo S One, 2014, 9 (2) :e86449.
|
|
[33]WANG L, WU XP, ZHANG W, et al.Evaluation of genetic susceptibility loci for chronic hepatitis B in Chinese:two independent case-control studies[J].PLo S One, 2011, 6 (3) :e17608.
|
DownLoad: