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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 11
Nov.  2017
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Article Contents

Research advances in immunoglobulin G4-related sclerosing cholangitis

DOI: 10.3969/j.issn.1001-5256.2017.11.042
  • Received Date: 2017-07-24
  • Published Date: 2017-11-20
  • Immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) is a new type of secondary sclerosing cholangitis which was discovered recently and has unknown pathogenesis.IgG4-SC is characterized by an increased serum level of immunoglobulin G4 (IgG4) , chronic progressive obstructive jaundice, diffuse or local infiltration of a large number of IgG4-positive plasma cells and lymphocytes, fibrosis, and obstructive phlebitis.This article reviews the diagnosis and treatment of IgG4-SC and its association with primary sclerosing cholangitis and cholangiocarcinoma.

     

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