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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 12
Dec.  2017
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Research advances in regorafenib in treatment of hepatocellular carcinoma

DOI: 10.3969/j.issn.1001-5256.2017.12.039
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  • Received Date: 2017-07-25
  • Published Date: 2017-12-20
  • Hepatocellular carcinoma ( HCC) is the most common malignant liver tumor, and there are limited systemic treatments for patients with advanced HCC. Regorafenib is an oral multi-kinase inhibitor, and phase III clinical trial has shown that regorafenib can significantly extend the median survival of patients with advanced HCC by 2. 8 months, which makes it a second-line drug approved by FDA for the treatment of advanced HCC, just after sorafenib. This article reviews the basic and clinical research on regorafenib in the field of HCC.

     

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