中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 6
Jun.  2018
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Article Contents

Research advances in drug-induced liver injury and existing problems in China

DOI: 10.3969/j.issn.1001-5256.2018.06.001
  • Received Date: 2018-03-31
  • Published Date: 2018-06-20
  • At present, Drug-induced liver injury (DILI) has become the most common cause of acute liver injury in clinical practice. This article elaborates on the pathogenesis of DILI, new biomarkers, liver tolerance to drug toxicity, adaptability and susceptibility, and testing threshold of alanine aminotransferase. Meanwhile, we should understand the development history of diagnostic scale, develop unified standards and understanding, and attach importance to DILI induced by medicinal herbs and dietary supplements, and in-depth studies on the pathogenesis of DILI should be performed to prevent or reduce DILI. There are several problems in DILI studies in China and obvious gaps between China and foreign countries, with a lack of basic research and blanks in clinical aspects. Therefore, we must strive to keep up with international research so that drugs can better serve the human.

     

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