|
[1]SCHON HT, BARTNECK M, BORKHAM-KAMPHORST E, et al.Pharmacological intervention in hepatic stellate cell activation and hepatic fibrosis[J].Front pharmacol, 2016, 7:33-55.
|
|
[2]ZHOU XL, YU SP.Role of Wnt signaling pathway in progression of liver cirrhosis[J].J Clin Hepatol, 2015, 31 (9) :1540-1542. (in Chinese) 周雪玲, 余水平.Wnt信号通路对肝硬化进展的影响[J].临床肝胆病杂志, 2015, 31 (9) :1540-1542.
|
|
[3]LEE Y, LEE JK, AHN SH, et al.Wnt signaling in glioblastoma and therapeutic opportunities[J].Lab Invest, 2016, 96 (2) :137-150.
|
|
[4]ZHAN T, RINDTORFF N, BOUTROS M.Wnt signaling in cancer[J].Oncogene, 2017, 36 (11) :1461-1473.
|
|
[5]GUI XY, SHI HF, CHEN YX.Function of the noncanonical Wnt pathway during bone development and metabolism[J].Chin J Exp Surg, 2017, 34 (8) :1437-1440. (in Chinese) 桂雪洋, 施鸿飞, 陈一心.非经典Wnt信号通路在骨发育和骨代谢中的作用[J].中华实验外科杂志, 2017, 34 (8) :1437-1440.
|
|
[6]WETTERE AJV, LAW JM, HINTON DE, et al.Anchoring hepatic gene expression with development of fibrosis and neoplasia in a toxicant-induced fish model of liver injury[J].Toxicologic Pathology, 2013, 41 (5) :744-760.
|
|
[7] AKHMETSHINA A, PALUMBO K, DEES C, et al.Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis[J].Nat Commun, 2012, 3:735-747.
|
|
[8]BAARSMA HA, HOEKE A, SPANJER, et al.Activation of Wnt/beta-catenin signaling in pulmonary fibroblasts by TGF-beta (1) is increased in chronic obstructive pulmonary disease[J].PLo S One, 2011, 6 (9) :e25450.
|
|
[9]TIAN X, ZHANG J, TAN TK, et al.Association ofβ-catenin with P-Smad3 but not LEF-1 dissociates in vitro profibrotic from anti-inflammatory effects of TGF-β1[J].J Cell Sci, 2013, 126 (1) :67-76.
|
|
[10]LABBE, LETAMENDIA A, ATTISANO L.Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and Wnt pathways[J].Proc Natl Acad Sci U S A, 2000, 97 (15) :8358-8363.
|
|
[11]GAO C, CHEN YG.Dishevelled:The hub of Wnt signaling[J].Cell Signal, 2010, 22 (5) :717-727.
|
|
[12]TULI R, TULI S, NANDI S, et al.Transforming growth factorbeta-mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogen-activated protein kinase and Wnt signaling cross-talk[J].J Biol Chem, 2003, 278 (42) :41227-41237.
|
|
[13]GUO X, RAMIREZ A, WADDELL DS, et al.Axin and GSK3-control Smad3 protein stability and modulate TGF-signaling[J].Gene Dev, 2008, 22 (1) :106-120.
|
|
[14]RASHID ST, HUMPHRIES JD, BYRON A, et al.Proteomic analysis of extracellular matrix from the hepatic stellate cell line LX-2identifies CYR61 and Wnt-5a as novel constituents of fibrotic liver[J].J Proteome Res, 2012, 11 (8) :4052-4064.
|
|
[15]LAU LF.CCN1/CYR61:The very model of a modern matricellular protein[J].Cell Mol Life Sci, 2011, 68 (19) :3149-3163.
|
|
[16]LI ZQ, DING W, SUN SJ, et al.Cyr61/CCN1 is regulated by Wnt/β-catenin signaling and plays an important role in the progression of hepatocellular carcinoma[J].PLo S One, 2012, 7 (4) :e35754.
|
|
[17]XIONG WJ, HU LJ, JIAN YC, et al.Wnt5a participates in hepatic stellate cell activation observed by gene expression profile and functional assays[J].World J Gastroenterol, 2012, 18 (15) :1745-1752.
|
|
[18]CRUCIAT CM, NIEHRS C.Secreted and transmembrane Wnt inhibitors and activators[J].Cold Spring Harb Perspect Biol, 2013, 5 (3) :a015081.
|
|
[19]YANAGIDA A, IWAISAKO K, HATANO E, et al.Downregulation of the Wnt antagonist Dkk2 links the loss of Sept4 and myofibroblastic transformation of hepatic stellate cells[J].Biochim Biophys Acta, 2011, 1812 (11) :1403-1411.
|
|
[20]XIAO C, WANG L, ZHU L, et al.Secreted frizzled-related protein 2 is epigenetically silenced and functions as a tumor suppressor in oral squamous cell carcinoma[J].Mol Med Rep, 2014, 10 (5) :2293-2298.
|
|
[21]XAVIER CP, MELIKOVA M, CHUMAN Y, et al.Secreted Frizzledrelated protein potentiation versus inhibition of Wnt3a/β-catenin signaling[J].Cell Signal, 2014, 26 (1) :94-101.
|
|
[22]KIM J, KIM S.In silico identification of sfrp1 as a hypermethylated gene in colorectal cancers[J].Genomics Inform, 2014, 12 (4) :171-180.
|
|
[23]ZHANG Y, YU X, WANG Z, et al.Pokeweed antiviral protein attenuates liver fibrosis in mice through regulating Wnt/Jnk mediated glucose metabolism[J].Saudi J Gastroenterol, 2018, 24 (3) :157.
|
|
[24]AKCORA B, STORM G, BANSAL R.Inhibition of canonical WNT signaling pathway byβ-catenin/CBP inhibitor ICG-001 ameliorates liver fibrosis in vivo through suppression of stromal CX-CL12[J].Biochim Biophys Acta, 2018, 1864 (3) :804-818.
|
|
[25]ZHAO Q, QIN CY, ZHAO ZH, et al.Epigenetic modifications in hepatic stellate cells contribute to liver fibrosis[J].Tohoku J Exp Med, 2013, 229 (1) :35-43.
|
|
[26]ZHU NL, WANG J, TSUKAMOTO H.The Necdin-Wnt pathway causes epigenetic peroxisome proliferator-activated receptor gamma repression in hepatic stellate cells[J].J Biol Chem, 2010, 285 (40) :30463-30471.
|
|
[27]VALLE A, LECARPENTIER Y, GUILLEVIN R, et al.Interactions between TGF-β1, canonical WNT/β-catenin pathway and PPARγin radiation-induced fibrosis[J].Oncotarget, 2017, 8 (52) :90579-90604.
|
|
[28]ZHANG F, LU S, HE J, et al.Ligand activation of PPARγby ligustrazine suppresses pericyte functions of hepatic stellate cells via SMRT-mediated transrepression of HIF-1α[J].Theranostics, 2018, 8 (3) :610-626.
|
|
[29]HASAN HF, ABDEL-RAFEI MK, GALAL SM.Diosmin attenuates radiation-induced hepatic fibrosis via boosting PPAR-γexpression and hampering mi R-17-5p activated canonical Wnt/β-catenin signaling[J].Biochem Cell Biol, 2017, 95 (3) :400-414.
|
|
[30]YEDID N, KALMA Y, MALCOV M, et al.The effect of a germline mutation in the APC gene onβ-catenin in human embryonic stem cells[J].BMC cancer, 2016, 16 (1) :95T2.
|
|
[31]SUN X, HE Y, MA TT, et al.Participation of mi R-200a in TGF-β1-mediated hepatic stellate cell activation[J].Mol Cell Biochem, 2014, 388 (1-2) :11-23.
|
|
[32]MA ZG, LV XD, ZHAN LL, et al.Human urokinase-type plasminogen activator gene-modified bone marrow-derived mesenchymal stem cells attenuate liver fibrosis in rats by down-regulating the Wnt signaling pathway[J].World J Gastroenterol, 2016, 22 (6) :2092-2103.
|
DownLoad: