中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 3
Mar.  2019
Turn off MathJax
Article Contents

Guidelines for clinical diagnosis and treatment of acute-on-chronic liver failure in traditional Chinese  medicine

DOI: 10.3969/j.issn.1001-5256.2019.03.009
  • Published Date: 2019-03-20
  • loading
  • [1] TREY C, DAVIDSON CS. The management of fulminant hepat-ic failure[J]. Prog Liver Dis, 1970, 3:282-298.
    [2] OHNISHI H, SUGIHARA J, MORIWAKI H, et al. Acute-on-chronic liver failure[J]. Ryoikibetsu Shokogun Shirizu, 1995, 7:217-219.
    [3] SARIN SK, KUMAR A, ALMEIDA JA, et al. Acute-on-chro-nic liver failure:Consensus recommendationsof the Asian Pa-cific Association for the Study of the liver (APASL) [J]. Hepa-tol Int, 2009, 3 (1) :269-282.
    [4] SARIN SK, KEDARISETTY CK, ABBAS Z, et al. Acute-on-chronic liver failure:Consensus recommendations of the AsianPacific Association for the Study of the Liver (APASL) 2014[J]. Hepatol Int, 2014, 8 (4) :453-471.
    [5] JALAN R, YURDAYDIN C, BAJAJ JS, et al. Toward an im-proved definition of acute-on-chronic liver failure[J]. Gas-troenterology, 2014, 147 (1) :4-10.
    [6] Chinese Society of Infectious Diseases and Parasitology, Chi-nese Society of Hepatology, Chinese Medical Association.Prevention and treatment of viral hepatitis[J]. Chin J InfectDis, 2001, 19 (1) :56-62. (in Chinese) 中华医学会传染病与寄生虫病学分会、肝病学分会.病毒性肝炎防治方案[J].中华传染病杂志, 2001, 19 (1) :56-62.
    [7] Liver Failure and Artificial Liver Group, Chinese Society of In-fectious Diseases, Chinese Medical Association; Severe LiverDiseases and Artificial Liver Group, Chinese Society of Hepa-tology, Chinese Medical Association. Diagnostic and treatmentguidelines for liver failure[J]. Inter J Epidemiol Infect Dis, 2006, 33 (4) :217-221. (in Chinese) 中华医学会感染病学分会肝衰竭与人工肝学组, 中华医学会肝病学分会重型肝病与人工肝学组.肝衰竭诊疗指南[J].国际流行病学传染病学杂志, 2006, 33 (4) :217-221.
    [8] Liver Failure and Artificial Liver Group, Chinese Society of Infec-tious Diseases, Chinese Medical Association; Severe LiverDiseases and Artificial Liver Group, Chinese Society of Hepa-tology, Chinese Medical Association. Guidelines for diagnosisand treatment of liver failure[J]. Chin J Clin Infect Dis, 2012, 5 (6) :321-327. (in Chinese) 中华医学会感染病学分会肝衰竭与人工肝学组, 中华医学会肝病学分会重型肝病与人工肝学组.肝衰竭诊治指南 (2012年版) [J].中华临床感染病杂志, 2012, 5 (6) :321-327.
    [9] Liver Failure and Artificial Liver Group, Chinese Society of In-fectious Diseases, Chinese Medical Association; Severe LiverDisease and Artificial Liver Group, Chinese Society of Hepatol-ogy, Chinese Medical Association. Guideline for diagnosis andtreatment of liver failure (2018) [J]. J Clin Hepatol, 2019, 35 (1) :38-44. (in Chinese) 中华医学会感染病学分会肝衰竭与人工肝学组, 中华医学会肝病学分会重型肝病与人工肝学组.肝衰竭诊治指南 (2018年版) [J].临床肝胆病杂志, 2019, 35 (1) :38-44.
    [10] LIU XY, HU JH, WANG HF, et al. Etiological analysis of 1977patients with acute liver failure, subacute liver failure and acute-on-chronic liver failure[J]. Chin J Hepatol, 2008, 16 (10) :772-775. (in Chinese) 刘晓燕, 胡瑾华, 王慧芬, 等. 1977例急性、亚急性、慢加急性肝衰竭患者的病因与转归分析[J].中华肝脏病杂志, 2008, 16 (10) :772-775.
    [11] China National Committee for Terms in Sciences and Technolo-gies. Traditional Chinese medicine terms for internal medicine, gynecology, and pediatrics[J]. Chin Sci Technol Terms J, 2011, 13 (5) :63-64. (in Chinese) 全国科学技术名词审定委员会.中医内科妇科儿科名词[J].中国科技术语, 2011, 13 (5) :63-64.
    [12] TIAN DL. Internal Medicine of Traditional Chinese Medicine[M]. Beijing:China Press of Traditional Chinese Medicine, 2005:295-296. (in Chinese) 田德禄.中医内科学[M].北京:中国中医药出版社, 2005:295-296.
    [13] WANG LF, LI J, LI FY, et al. A multicentered, randomize-controlled trial of integrative medicine for acute-on-chronic (subacute) liver failure[J]. J Tradit Chin Med, 2013, 54 (22) :1922-1925. (in Chinese) 王立福, 李筠, 李丰衣, 等.中医辨证联合西药治疗慢加急性 (亚急性) 肝衰竭多中心随机对照研究[J].中医杂志, 2013, 54 (22) :1922-1925.
    [14] LIU HM, WANG XB, HOU YX, et al. Efficacy and safety ofintegrative medical program based on blood cooling and de-toxification recipein treaing patients with hepatitis B virus relat-ed acute-on-chronic liver failure:A randomized controlledclinical study[J]. Chin J Integr Trad West Med, 2014, 34 (4) :412-417. (in Chinese) 刘慧敏, 王宪波, 侯艺鑫, 等.解毒凉血方加减治疗乙型肝炎慢加急性肝衰竭的随机对照临床研究[J].中国中西医结合杂志, 2014, 34 (4) :412-417.
    [15] LIU HM, WANG XB, CHANG YJ, et al. Systematic review andmeta-analysis of randomized controlled trials of integrativemedicine therapy for treatment of chronic severe hepatitis[J].J Chin Integr Med, 2012, 10 (11) :1211-1228. (in Chinese) 刘慧敏, 王宪波, 常玉娟, 等.中西医结合治疗慢性重型肝炎随机对照试验的系统评价和meta分析[J].中西医结合学报, 2012, 10 (11) :1211-1228.
    [16] HU X, ZHANG Y, CHEN G, et al. Distribution of TraditionalChinese Medicine patterns in 324 cases with hepatitis B-relat-ed acute-on-chronic liver failure:A prospective, cross-sectional survey[J]. J Tradit Chin Med, 2012, 32 (4) :538-544.
    [17] LUO JX, HU XY, ZHANG Y, et al. Syndrome differentiationand treatment of hepatitis B-related acute-on-chronic liverfailure by stage:A preliminary analysis of therapeutic principle[J]. Chin J Integr Tradit West Med Liver Dis, 2013, 23 (5) :311-313. (in Chinese) 骆建兴, 扈晓宇, 张扬, 等.浅析分期论治乙型肝炎相关性慢加急性肝衰竭的辨治思想[J].中西医结合肝病杂志, 2013, 23 (5) :311-313.
    [18] XU LH, TAN SZ, ZHAO L, et al. Distribution characteristics ofTCM syndromes of hepatitis B virus-related acute-on-chro-nic liver failure:A clinical study[J]. Jiangsu J Traditi ChinMed, 2013, 45 (12) :22-23. (in Chinese) 徐立华, 谭善忠, 赵磊, 等.乙肝病毒相关慢加急性肝衰竭中医证候分布特点的临床研究[J].江苏中医药, 2013, 45 (12) :22-23.
    [19] SHEN NL, GUO LY, SHI HY, et al. Research of liver failuresyndromes and evolution regularity[J]. J Emerg Tradit ChinMed, 2014, 23 (8) :1434-1435, 1446. (in Chinese) 沈南兰, 郭丽颖, 时海艳, 等.肝衰竭中医证候归纳及演变规律研究[J].中国中医急症, 2014, 23 (8) :1434-1435, 1446.
    [20] WANG XJ, LI XH, TIAN YM. Clinical effects of 146 cases ofchronic severe hepatitis treated by comprehensive treatmentand integrated traditional Chinese medicine and western medi-cine[J]. Chin J Integr Tradit West Med Liver Dis, 2011, 21 (3) :131-134. (in Chinese) 汪晓军, 李秀惠, 田一梅. 146例慢性重型肝炎综合治疗与中西医结合治疗疗效比较[J].中西医结合肝病杂志, 2011, 21 (3) :131-134.
    [21] DANG ZQ, YANG GH, MA YJ, et al. Synergistic effect of multi-ways chinese medication on routine therapy for hepatitis Bvirus related acute-on-chronic liver failure[J]. J Tradit ChinMed, 2012, 53 (24) :2109-2111. (in Chinese) 党中勤, 杨国红, 马应杰, 等.中医多途径给药对乙型肝炎慢加急性肝衰竭西医常规疗法的增效作用[J].中医杂志, 2012, 53 (24) :2109-2111.
    [22] ZHU WF, SUN KW, CHEN B, et al. Effect of Wenyang JieduHuayu prescription on intestinal bacteria in patients with HBVrelated liver failure[J]. Chin J Integr Tradit West Med LiverDis, 2014, 24 (4) :214-216. (in Chinese) 朱文芳, 孙克伟, 陈斌, 等.温阳解毒化瘀方对HBV相关肝衰竭患者肠道菌群的影响[J].中西医结合肝病杂志, 2014, 24 (4) :214-216.
    [23] ZHOU XZ, HUANG QG, SUN XF, et al. Study on the principleof TCM syndrome distribution in patients with liver failure[J]. JTradit Chin Med Univ Hunan, 2013, 33 (1) :64-66. (in Chi-nese) 周小舟, 黄俏光, 孙新峰, 等.肝衰竭中医证候分布规律研究[J].湖南中医药大学学报, 2013, 33 (1) :64-66.
    [24] ZHANG QY, LI XH, WANG RB, et al. Distribution and combi-nation law of TCM syndromes of chronic severe viral hepatitis B[J]. Beijing J Tradit Chin Med, 2008, 27 (2) :87-90. (inChinese) 张秋云, 李秀惠, 王融冰, 等.慢性病毒性乙型重型肝炎中医证候分布及组合规律研究[J].北京中医药, 2008, 27 (2) :87-90.
    [25] Specialized Committee of Liver Diseases, China Association ofChinese Medicine. The standards of traditional Chinese medi-cine syndrome differentiation for viral hepatitis (on trial) [J]. JTradit Chin Med, 1992, 33 (5) :39-40. (in Chinese) 中国中医药学会内科肝病专业委员会.病毒性肝炎中医辨证标准 (试行) [J].中医杂志, 1992, 33 (5) :39-40.
    [26] Beijing Hospital of Traditional Chinese Medicine. Selected clinicalexperience of Guan Youbo[M]. Beijing:People's Health Publish-ing House, 1979:23. (in Chinese) 北京市中医院.关幼波临床经验选[M].北京:人民卫生出版社, 1979:23.
    [27] GUAN YB. Syndrome differentiation and treatment of jaundice[J]. Chin J Integ Med Cardio-Cerebrovascular Dis, 1986, 3:2-3. (in Chinese) 关幼波.黄疸证的辨证施治[J].中医药研究杂志, 1986, 3:2-3.
    [28] WANG CB. Integrated traditional Chinese and Western medi-cine therapy for severe cholestatic hepatitis and severe chronichepatitis:Thoughts and medication[J]. Chin J Integr TraditWest Med Liver Dis, 1998, supplementary issue (volumeⅡ) :4-7. (in Chinese) 汪承柏.中西医结合治疗重症淤胆肝炎, 慢性重型肝炎思路方法与用药研究[J].中西医结合肝病杂志, 1998, 增刊 (下) :4-7.
    [29] ZHOU ZY. Syndrome differentiation-based treatment of se-vere hepatitis[J]. J New Chin Med, 2002, 34 (3) :3-6. (inChinese) 周仲瑛.重症肝炎辨治述要[J].新中医, 2002, 34 (3) :3-6.
    [30] TAO XP, ZHOU ZY, YAO NL. A discussion on diagnosis andtreatment of severe hepatitis with fighting of stasis and heat[J]. Chin J Basic Med Tradit Chin Med, 2004, 10 (1) :51-52. (in Chinese) 陶夏平, 周仲瑛, 姚乃礼.重型肝炎瘀热相搏证治探讨[J].中国中医基础医学杂志, 2004, 10 (1) :51-52.
    [31] HUANG WQ, JIANG T, JIANG GH, et al.“Severance and Re-version”therapy:Theory and practice[J]. Pract Tradit ChinIntern Med, 1991, 5 (2) :35-36. (in Chinese) 黄为群, 蒋通, 姜光华, 等.“截断扭转”疗法的理论与实践[J].实用中医内科杂志, 1991, 5 (2) :35-36.
    [32] CHEN NS, SUN KW. Speedy treatment of serious hepatitis[J]. J New Chin Med, 2001, 33 (1) :3-4. (in Chinese) 谌宁生, 孙克伟.重症肝炎从快速截断论治[J].新中医, 2001, 33 (1) :3-4.
    [33] QIAN Y. Severance and reversion therapy for severe chronichepatitis[J]. Beijing J Tradit Chin Med, 2008, 27 (2) :85-87. (in Chinese) 钱英.截断逆挽法治疗慢性重型肝炎[J].北京中医药, 2008, 27 (2) :85-87.
    [34] HU JH, QIAN Y, YAO NL, et al. Treatment of chronic severehepatitis B by Jieduan Niwan method[J]. Chin J Integr TraditWest Med Liver Dis, 2010, 20 (4) :200-203. (in Chinese) 胡建华, 钱英, 姚乃礼, 等.“截断逆挽法”治疗慢性乙型重型肝炎临床疗效观察[J].中西医结合肝病杂志, 2010, 20 (4) :200-203.
    [35] LI HM. Therapy rule of“Nourishing Kidney to Produce Marrowand Form Liver”[J]. Chin Arch Tradit Chin Med, 2012, 30 (5) :937-940. (in Chinese) 李瀚旻.论“补肾生髓成肝”治疗法则[J].中华中医药学刊, 2012, 30 (5) :937-940.
    [36] WANG XB, LI B, LIU HM. Experience in detoxicating, blood-cooling, spleen-strengthening, and dampness-removingtherapy for hepatitis B-related acute-on-chronic liver failure[J]. J Tradit Chin Med, 2012, 53 (20) :1772-1776. (in Chi-nese) 王宪波, 李斌, 刘慧敏.解毒凉血、健脾化湿法治疗乙型肝炎慢加急性肝功能衰竭体会[J].中医杂志, 2012, 53 (20) :1772-1776.
    [37] LIU HM, WANG XB, HOU YX, et al. Clinical observation ontoxin-resolving blood-cooling formula combined with west-ern medicine for 64 cases of hepatitis B related acute-on-chronic liver failure[J]. J Tradit Chin Med, 2013, 54 (21) :1829-1833. (in Chinese) 刘慧敏, 王宪波, 侯艺鑫, 等.解毒凉血方联合西药治疗乙型肝炎慢加急性肝衰竭患者64例临床观察[J].中医杂志, 2013, 54 (21) :1829-1833.
    [38] WANG N, WANG S, TANG N, et al. A detoxification and sta-sis-resolving granules-dominated combination therapy inpatients with hepatitis B acute-on-chronic liver failure[J].Chin J Integr Tradit West Med Liver Dis, 2014, 24 (4) :207-209. (in Chinese) 王娜, 王沙, 唐农, 等.以解毒化瘀颗粒为主导中西医结合治疗乙型慢加急性肝衰竭的临床研究[J].中西医结合肝病杂志, 2014, 24 (4) :207-209.
    [39] HU XY, ZHANG Y, CHEN G, et al. A prospective cohort studyon the influence of high doses of herbs for clearing heat andresolving stasis on survival rates in patients with hepatitis B-related acute-on-chronic liver failure[J]. J Chin IntegrMed, 2012, 10 (2) :176-185. (in Chinese) 扈晓宇, 张扬, 陈果, 等.大剂量清热化瘀中药对乙型肝炎相关性慢加急性肝衰竭生存影响的前瞻性队列研究[J].中西医结合学报, 2012, 10 (2) :176-185.
    [40] ZHANG RK, ZHANG H. Efficacy of transmetil combined withYinzhihuang injection in treatment of severe chronic hepatitis:A report of 33 cases[J]. J Guiyang Coll Tradit Chin Med, 2002, 24 (3) :34-35. (in Chinese) 张如坤, 张红.思美泰联合茵栀黄注射液治疗慢性重型肝炎33例疗效观察[J].贵阳中医学院学报, 2002, 24 (3) :34-35.
    [41] GU XB, LIU HX. Clinical effect of multimodality therapy withthe addition of Kuhuang injection in treatment of severe chronichepatitis[J]. Tradit Chin Drug Res Clin Pharmacol, 1998, 9 (4) :207-208, 251. (in Chinese) 顾锡炳, 刘海肃.加用苦黄注射液综合治疗慢性重型肝炎的疗效观察[J].中药新药与临床药理, 1998, 9 (4) :207-208, 251.
    [42] CHEN YQ, MAO DW, TANG N, et al. Efficacy of modifiedYinchen Sini Tang in acute-on-chronic liver failure[J]. ChinJ Exp Med Formul, 2015, 21 (18) :163-166. (in Chinese) 陈月桥, 毛德文, 唐农, 等.茵陈四逆汤加减治疗慢加急性肝衰竭[J].中国实验方剂学杂志, 2015, 21 (18) :163-166.
    [43] ZHANG Y, WU YY, TAN SZ, et al. Clinical observation onchronic severe hepatitis B treated by principle of strengtheningVital Qi and the spleen based on the mechanism of deficiencyin Vital Qi[J]. J Emerg Tradit Chin Med, 2012, 21 (6) :872-873, 892. (in Chinese) 张旸, 吴银亚, 谭善忠, 等.基于正虚机制观察益气健脾法治疗慢性乙型肝炎肝衰竭的临床疗效[J].中国中医急症, 2012, 21 (6) :872-873, 892.
    [44] LIAN YN, XU LH, TAN SZ, et al. Effects of treatment on T lym-phocyte frequency with principle of strengthening Vital Qi andthe spleen based on the mechanism of deficiency in Vital Qi inpatients with HBV-ACLF[J]. J Emerg Tradit Chin Med, 2015, 24 (12) :2225-2228. (in Chinese) 廉亚男, 徐立华, 谭善忠, 等.基于正虚病机的益气健脾法治疗对HBV-ACLF患者外周血T淋巴细胞的影响[J].中国中医急症, 2015, 24 (12) :2225-2228.
    [45] LI HM, YE ZH, ZHANG J, et al. Clinical trial with traditionalChinese medicine intervention“tonifying the kidney to promoteliver regeneration and repair by affecting stem cells and theirmicroenvironment” for chronic hepatitis B-associated liverfailure[J]. World J Gastroenterol, 2014, 20 (48) :18458-18465.
    [46] HUANG HN, HUANG JJ, WANG ZC, et al. Clinical efficacy ofentecavir combined with Rougan Huaqian granules in treatmentof chronic hepatitis B liver failure[J]. Mod J Integr Tradit ChinWest Med, 2014, 23 (33) :3700-3703. (in Chinese) 黄鸿娜, 黄晶晶, 王振常, 等.恩替卡韦联合柔肝化纤颗粒治疗慢性乙型肝炎肝衰竭的临床观察[J].现代中西医结合杂志, 2014, 23 (33) :3700-3703.
    [47] LIU LM, WANG LT, CHEN JJ, et al. Effect of Qingkai Granuleon patients with subclinical hepatic encephalopathy of intelli-gence test and evoked potential[J]. Chin Tradit Patent Med, 2006, 28 (3) :372-375. (in Chinese) 刘龙民, 王灵台, 陈建杰, 等.清开颗粒对亚临床肝性脑病患者智力测试与诱发电位的影响[J].中成药, 2006, 28 (3) :372-375.
    [48] HUANG GY, MAO DW, LONG FL, et al. Retention enema withrhubarb decoction in treating hepatic encephalopathy:Resultsfrom a multi-center clinical trial[J]. Liaoning J Tradit ChinMed, 2011, 38 (7) :1364-1366. (in Chinese) 黄古叶, 毛德文, 龙富立, 等.大黄煎剂保留灌肠治疗肝性脑病的多中心临床研究[J].辽宁中医杂志, 2011, 38 (7) :1364-1366.
    [49] WANG N, WANG MG, MAO DW, at el. Clinical effect of rhu-barb decoction in treatment of type A hepatic encephalopathy[J]. Lishizhen Med Mater Med Res, 2015, 26 (5) :1169-1171. (in Chinese) 王娜, 王明刚, 毛德文, 等.大黄煎剂治疗A型肝性脑病的临床疗效观察[J].时珍国医国药, 2015, 26 (5) :1169-1171.
    [50] ZHOU ZE, LU P, HAN L, et al. A Multi-center randomizedparallel-controlled clinical study on efficiency of rhubarb de-coction retention enema combined with Western medicine intreating hepatic encephalopathy[J]. Liaoning J Tradit ChinMed, 2014, 41 (9) :1918-1921. (in Chinese) 周智恩, 卢萍, 韩丽, 等.大黄煎剂保留灌肠联合西药治疗肝性脑病多中心随机平行对照研究[J].辽宁中医杂志, 2014, 41 (9) :1918-1921.
    [51] Branch of Gastrointestinal Diseases, China Association of Chi-nese Medicine. Expert consensus on TCM diagnosis and treat-ment of ascites due to cirrhosis (2017) [J]. J Clin Hepatol, 2017, 33 (9) :1621-1626. (in Chinese) 中华中医药学会脾胃病分会.肝硬化腹水中医诊疗专家共识意见 (2017) [J].临床肝胆病杂志, 2017, 33 (9) :1621-1626.
    [52] WANG RB, WANG XB, SUN FX, et al. Clinical effect of detoxi-cating and blood-cooling therapy in treatment of chronic se-vere hepatitis B[J]. Beijing J Tradit Chin Med, 2008, 27 (2) :83-85. (in Chinese) 王融冰, 王宪波, 孙凤霞, 等.解毒凉血法治疗慢性乙型重型肝炎[J].北京中医药, 2008, 27 (2) :83-85.
    [53] WANG RB, LIU JM, WU YZ, et al. Clinical study of compoundformula Qingdutang on intestinal endotoxemia in patients withliver disease[J]. Chin J Integr Tradit West Med Liver Dis, 2004, 14 (3) :135-137. (in Chinese) 王融冰, 刘军民, 吴云忠, 等.清毒汤治疗肝病肠源性内毒素症临床观察[J].中西医结合肝病杂志, 2004, 14 (3) :135-137.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (1848) PDF downloads(527) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return