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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 3
Mar.  2019
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Article Contents

Advances in the application of transient elastography in noninvasive diagnosis of liver fibrosis

DOI: 10.3969/j.issn.1001-5256.2019.03.041
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  • Received Date: 2018-10-08
  • Published Date: 2019-03-20
  • Liver biopsy is the most sensitive and specific method for the diagnosis and staging of liver fibrosis, but its invasiveness and limi-tations have promoted the wide application of noninvasive evaluation methods for liver fibrosis in clinical practice in recent years. Variousstudies have proved the diagnostic efficiency of transient elastography ( TE) in chronic liver diseases of various etiologies, such as viral hepa-titis, nonalcoholic fatty liver disease, alcoholic liver disease, and autoimmune liver disease, especially in liver fibrosis and liver cirrhosis, and therefore, it has been incorporated into clinical practice guidelines in many countries. However, the diagnostic efficiency of TE in liverfibrosis is affected by several factors including aminotransferases, bilirubin, liver inflammation, and steatosis. Several noninvasive methodsshould be used in combination based on etiology to improve diagnostic accuracy.

     

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