中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 3
Mar.  2019
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Article Contents

Biological function and regulatory mechanism of epithelial-mesenchymal transition-related long non-coding RNAs in liver cancer

DOI: 10.3969/j.issn.1001-5256.2019.03.046
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  • Received Date: 2018-11-13
  • Published Date: 2019-03-20
  • Liver cancer has a high degree of malignancy, and many oncogenes and tumor suppressor genes play an important regulatory rolein the development and progression of liver cancer. Epithelial-mesenchymal transition ( EMT) is a biological process in which epithelialcells transform into mesenchymal cells, which can increase the migration and invasion abilities of tumor cells. Long non-coding RNAs ( ln-cRNAs) can regulate EMT process in various ways. This article reviews the research advances in the main biological functions and regulatorymechanisms of EMT-related lncRNAs in liver cancer.

     

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