中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 4
Apr.  2019
Turn off MathJax
Article Contents

Radiological evaluation of the reversal of liver fibrosis and cirrhosis

DOI: 10.3969/j.issn.1001-5256.2019.04.004
  • Received Date: 2019-01-08
  • Published Date: 2019-04-20
  • Noninvasive methods for the evaluation of liver fibrosis have been widely validated with liver biopsy as the gold standard. This article elaborates on the application of various imaging methods in the evaluation of liver fibrosis and their prospects in evaluating the reversal of liver fibrosis. Transient elastography is the main imaging method for evaluating the reversal of liver fibrosis and can show the improvement in liver fibrosis via liver stiffness measurement, but the association between the reduction in liver stiffness measurement and the improvement of liver fibrosis remains unclear.

     

  • loading
  • [1]EUGENE R, SCHIFF, MICHAEL F. Schiff's hepatology[M].1th, HUANG ZQ. Beijing:Chemical Industry Press, 2006:263. (in Chinese) Eugene R, Schiff, Michael F.希夫肝脏病学[M]. 1版, 黄志强, 译.北京:化学工业出版社, 2006:263.
    [2]ALLAN R, THOIRS K, PHILLIPS M. Accuracy of ultrasound to identify chronic liver disease[J]. World J Gastroenterol, 2010, 16 (28) :3510-3520.
    [3]CHEN YP, DAI L, WANG JL, et al. Model consisting of ultrasonographic and simple blood indexes accurately identify compensated hepatitis B cirrhosis[J]. J Gastroenterol Hepatol, 2008, 23 (8) :1228-1234.
    [4]HUNG CH, LU SN, WANG JH, et al. Correlation between ultrasonographic and pathologic diagnoses of hepatitis B and C virus-related cirrhosis[J]. J Gastroenterol, 2003, 38 (2) :153-157.
    [5]MOON KM, KIM G, BAIK SK, et al. Ultrasonographic scoring system score versus liver stiffness measurement in prediction of cirrhosis[J]. Clin Mol Hepatol, 2013, 19 (4) :389-398.
    [6]BARR RG, FERRAIOLI G, PALMERI ML, et al. Elastography assessment of liver fibrosis, society of radiologists in ultrasound consensus conference statement[J]. Ultrasound Q, 2016, 32 (2) :94-107.
    [7]FERRAIOLI G, WONG VWS, CASTERA L, et al. Liver Ultrasound elastography:An update to the world federation for ultrasound in medicine and biology guideline and recommendation[J]. Ultrasound Med Biol, 2018, 44 (12) :2419-2440.
    [8]FRAQUELLI M, RIGAMONTI C, CASAZZA G, et al. Reproducibility of transient elastography in the evaluation of liver fibrosis in patients with chronic liver disease[J]. Gut, 2007, 56:968-973.
    [9]CHEN YP, PENG J, HOU JL. Non-invasive assessment of liver fibrosis in patients with chronic hepatitis B[J]. Hepatol Int, 2013, 7 (2) :356-368.
    [10]Review Panel for Liver Stiffness Measurement. Recommendations for the clinical application of transient elastography in liver fibrosis assessment[J]. Chin J Hepatol, 2013, 21 (6) :420-424. (in Chinese) 肝脏硬度评估小组.瞬时弹性成像技术诊断肝纤维化专家意见[J].中华肝脏病杂志, 2013, 21 (6) :420-424.
    [11]LIANG XE, CHEN YP, ZHANG Q, et al. Dynamic evaluation paralleled with bilirubin and ALT normalization to improve diagnostic accuracy of Fibroscan in patients with hepatitis B exacerbation[J]. J Viral Hepat, 2011, 18 (12) :884-891.
    [12] CHAN HL, WONG GL, CHOI PC, et al. Alanine aminotransferase-based algorithms of liver stiffness measurement by transient elastography (Fibroscan) for liver fibrosis in chronic hepatitis B[J]. J Viral Hepat, 2009, 16 (1) :36-44.
    [13]CHEN YP, LIANG XE, DAI L, et al. Improving transient elastography performance for detecting hepatitis B cirrhosis[J].Dig Liver Dis, 2012, 44 (1) :61-66.
    [14]CHEN YP, LIANG XE, ZHANG Q, et al. Larger biopsies evaluation of transient elastography for detecting advanced fibrosis in patients with compensated chronic hepatitis B[J]. J Gastroenterol Hepatol, 2012, 27 (7) :1219-1226.
    [15]HALL TJ, MILKOWSKI A, GARRA B, et al. RSNA/QIBA:Shear wave speed as a biomarker for liver fibrosis staging[J]. Ultrasonics Symposium (IUS) , 2013, 2013:397-400.
    [16]FRIEDRICH-RUST M, NIERHOFF J, LUPSOR M, et al. Performance of acoustic radiation force impulse imaging for the staging of liver fibrosis:A pooled meta-analysis[J]. J Viral Hepat, 2012, 19 (2) :e212-e219.
    [17]BOTA S, HERKNER H, SPOREA I, et al. Meta-analysis:ARFI elastography versus transient elastography for the evaluation of liver fibrosis[J]. Liver Int, 2013, 33 (8) :1138-1147.
    [18]HUANG Z, ZHENG J, ZENG J, et al. Normal liver stiffness in healthy adults assessed by real-time shear wave elastography and factors that influence this method[J]. Ultrasound Med Biol, 2014, 40 (11) :2549-2555.
    [19]LEUNG VY, SHEN J, WONG VW, et al. Quantitative elastography of liver fibrosis and spleen stiffness in chronic hepatitis B carriers:Comparison of shear-wave elastography and transient elastography with liver biopsy correlation[J]. Radiology, 2013, 269 (3) :910-918.
    [20]CASSINOTTO C, LAPUYADE B, MOURIES A, et al. Non-invasive assessment of liver fibrosis with impulse elastography:Comparison of supersonic shear imaging with ARFI and FibroScan[J]. J Hepatol, 2014, 61 (3) :550-557.
    [21]MANNING DS, AFDHAL NH. Diagnosis and quantitation of fibrosis[J]. Gastroenterology, 2008, 134 (6) :1670-1681.
    [22]HOODESHENAS S, YIN M, VENKATESH SK. Magnetic resonance elastography of liver:Current update[J]. Top Magn Reson Imaging, 2018, 27 (5) :319-333.
    [23]SINGH S, VENKATESH SK, WANG Z, et al. Diagnostic performance of magnetic resonance elastography in staging liver fibrosis:A systematic review and meta-analysis of individual participant data[J]. Clin Gastroenterol Hepatol, 2015, 13 (3) :440-451. e6.
    [24] WANLESS IR, NAKASHIMA E, SHERMAN M, et al. Regression of human cirrhosis. Morphologic features and the genesis of incomplete septal cirrhosis[J]. Arch Pathol Lab Med, 2000, 12490 (11) :1599-1607.
    [25]HYTIROGLOU P, THEISE ND. Regression of human cirrhosis:An update, 18 years after the pioneering article by Wanless et al[J]. Virchows Archiv, 2018, 473 (1) :15-22.
    [26]ENOMOTO M, MORI M, OGAWA T, et al. Usefulness of transient elastography for assessment of liver fibrosis in chronic hepatitis B:Regression of liver stiffness during entecavir therapy[J]. Hepatol Res, 2010, 40 (9) :853-861.
    [27]WONG GL, WONG VW, CHOI PC, et al. On-treatment monitoring of liver fibrosis with transient elastography in chronic hepatitis B patients[J]. Antivir Ther, 2011, 16 (2) :165-172.
    [28]DONG XQ, WU Z, LI J, et al. Declining in liver stiffness can not indicate fibrosis regression in patients with chronic hepatitis B:A 78-week prospective study[J]. J Gastroenterol Hepatol, 2018.[Epub ahead of print]
    [29]LIANG X, TAN D, XIE Q, et al. Interpretation of liver stiffness measurement-based approach for the monitoring of hepatitis B patients with antiviral therapy:A 2-year prospective study[J]. J Viral Hepat, 2018, 25 (3) :296-305.
    [30]CHAN HL, WONG GL, CHOI PC, et al. Alanine aminotransferasebased algorithms of liver stiffness measurement by transient elastography (Fibroscan) for liver fibrosis in chronic hepatitis B[J]. J Viral Hepat, 2009, 16 (1) :36-44.
    [31] SUN Y, ZHOU J, WANG L, et al. New classification of liver biopsy assessment for fibrosis in chronic hepatitis B patients before and after treatment[J]. Hepatology, 2017, 65 (5) :1438-1450.
    [32]KONG Y, SUN Y, ZHOU J, et al. Early steep decline of liver stiffness predicts histological reversal of fibrosis in chronic hepatitis B patients treated with entecavir[J]. J Viral Hepat, 2019.[Epub ahead of print]
    [33]MAURO E, CRESPO G, MONTIRONI C, et al. Portal pressure and liver stiffness measurements in the prediction of fibrosis regression after sustained virological response in recurrent hepatitis C[J]. Hepatology, 2018, 67 (5) :1683-1694.
    [34]HARTL J, EHLKEN H, SEBODE M, et al. Usefulness of biochemical remission and transient elastography in monitoring disease course in autoimmune hepatitis[J]. J Hepatol, 2018, 68 (4) :754-763.
    [35]European Association for the Study of the Liver, Asociación Latinoamericana parael Estudio del Hígado. EASL-ALEH clinical practice guidelines:Non-invasive tests for evaluation of liver disease severity and prognosis[J]. J Hepatol, 2015, 63:237-264.
    [36]PINZANI M. Liver fibrosis in the post-HCV era[J]. Semin Liver Dis, 2015, 35 (2) :157-165.
    [37]WU S, KONG Y, PIAO H, et al. On-treatment changes of liver stiffness at week 26 could predict 2-year clinical outcomes in HBV-related compensated[J]. Liver Int, 2018, 38 (6) :1045-1054.
    [38]HEZODE C, CASTERA L, ROUDOT-THORAVAL F, et al. Liver stiffness diminishes with antiviral response in chronic hepatitis C[J]. Aliment Pharmacol Ther, 2011, 34 (6) :656-663.
    [39]KIM SU, PARK JY, KIM DY, et al. Non-invasive assessment of changes in liver fibrosis via liver stiffness measurement in patients with chronic hepatitis B:Impact of antiviral treatment on fibrosis regression[J]. Hepatol Int, 2010, 4 (4) :673-680.
    [40]D’AMBROSIO R, AGHEMO A, FRAQUELLI M, et al. The diagnostic accuracy of Fibroscan for cirrhosis is influenced by liver morphometry in HCV patients with a sustained virological response[J]. J Hepatol, 2013, 59 (2) :251-256.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (1600) PDF downloads(441) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return