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ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 9
Sep.  2019
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Article Navigation >  Journal of Clinical Hepatology  > 2019  >  35(9): 1903-1908

Differences in the diagnostic criteria for acute-on-chronic liver failure between the East and the West

DOI: 10.3969/j.issn.1001-5256.2019.09.003

  • The First Affiliated Hospital of Medical School of Zhejiang University, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases

  • Received Date: 2019-06-17
  • Published Date: 2019-09-20
    Abstract
  • Acute-on-chronic liver failure ( ACLF) is a serious threat to global public health, with a mortality rate of as high as 50%-90% after comprehensive medical treatment, and early diagnosis and treatment are of vital importance to reducing the mortality rate of ACLF. Due to the difference in major etiologies of ACLF between the East and the West, there are still no universally accepted diagnostic criteria for ACLF, with controversies over whether the underlying disease of liver cirrhosis should be one of the diagnostic criteria for ACLF.This article reviews the latest research advances in the definition, diagnostic criteria, predisposing factors, and pathogenesis of ACLF, in order to provide a theoretical basis for the development of new treatment strategies and international guidelines.

     

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