中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 9
Sep.  2019
Turn off MathJax
Article Contents

Current status of the diagnose and treatment of spontaneous bacterial peritonitis

DOI: 10.3969/j.issn.1001-5256.2019.09.043
Research funding:

 

  • Received Date: 2019-05-10
  • Published Date: 2019-09-20
  • Infection is a common complication in patients with liver cirrhosis, and spontaneous bacterial peritonitis ( SBP) is the most common type of infection. This article summarizes the formation process of the diagnostic criteria of SBP based on a number of multinuclear cells of > 250 cells/μl in ascites, limitations of ascites cell counting, and the current status of the treatment of SBP. It is pointed out that novel biomarkers with high sensitivity are needed for the diagnosis of SBP diagnose, in order to guide empirical antimicrobial treatment and optimize the management of patients with SBP in clinical practice.

     

  • loading
  • [1]PIANO S, BROCCA A, MARESO S, et al.Infections complicating cirrhosis[J].Liver Int, 2018, 38 (Suppl 1) :126-133.
    [2]MCKE MM, RUMYANTSEVA T, MCKE VT, et al.Bacterial infection-triggered acute-on-chronic liver failure is associated with increased mortality[J].Liver Int, 2018, 38 (4) :645-653.
    [3]PIANO S, BARTOLETTI M, TONON M, et al.Assessment of Sepsis-3 criteria and quick SOFA in patients with cirrhosis and bacterial infections[J].Gut, 2018, 67 (10) :1892-1899.
    [4]GUNNARSDOTTIR SA, SADIK R, SHEV S, et al.Small intestinal motility disturbances and bacterial overgrowth in patients with liver cirrhosis and portal hypertension[J].Am J Gastroenterol, 2003, 98 (6) :1362-1370.
    [5]Chinese Society of Hepatology, Chinese Medical Association.Guidelines on the management of ascites and complications in cirrhosis[J].J Clin Hepatol, 2017, 33 (10) :1847-1863. (in Chinese) 中华医学会肝病学分会.肝硬化腹水及相关并发症的诊疗指南[J].临床肝胆病杂志, 2017, 33 (10) :1847-1863.
    [6]NOBLE CA, PERRY IH, MARQUIS HH.Hepatic cirrhosis with encapsulated peritonitis:Report of case[J].Cal West Med, 1936, 45 (2) :172-174.
    [7]KLINE MM, MCCALLUM RW, GUTH PH.The clinical value of ascitic fluid culture and leukocyte count studies in alcoholic cirrhosis[J].Gastroenterology, 1976, 70 (3) :408-412.
    [8]JONES SR.The absolute granulocyte count in ascites fluid.An aid to the diagnosis of spontaneous bacterial peritonitis[J].West J Med, 1977, 126 (5) :344-346.
    [9]HOEFS JC, CANAWATI HN, SAPICO FL, et al.Spontaneous bacterial peritonitis[J].Hepatology, 1982, 2 (4) :399-407.
    [10]HOEFS JC, RUNYON BA.Spontaneous bacterial peritonitis[J].Dis Mon, 1985, 31 (9) :1-48.
    [11]ALBILLOS A, CUERVAS-MONS V, MILLN I, et al.Ascitic fluid polymorphonuclear cell count and serum to ascites albumin gradient in the diagnosis of bacterial peritonitis[J].Gastroenterology, 1990, 98 (1) :134.
    [12]SORT P, NAVASA M, ARROYO V, et al.Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis[J].N Engl JMed, 1999, 341 (6) :403-409.
    [13]RIMOLA A, GARCIA-TSAO G, NAVASA M, et al.Diagnosis, treatment and prophylaxis of spontaneous bacterial peritonitis:A consensus document.International Ascites Club[J].JHepatol, 2000, 32 (1) :142-153.
    [14]LE S, SPELMAN T, CHONG CP, et al.Could adherence to quality of care indicators for hospitalized patients with cirrhosis-related ascites improve clinical outcomes?[J].Am J Gastroenterol, 2016, 111 (1) :87-92.
    [15]NING NZ, LI T, ZHANG JL, et al.Clinical and bacteriological features and prognosis of ascitic fluid infection in Chinese patients with cirrhosis[J].BMC Infect Dis, 2018, 18 (1) :253.
    [16]ICHOU L, CARBONELL N, RAUTOU PE, et al.Ascitic fluid TREM-1 for the diagnosis of spontaneous bacterial peritonitis[J].Gut, 2016, 65 (3) :536-538.
    [17]CULLARO G, KIM G, PEREIRA MR, et al.Ascites neutrophil gelatinase-associated lipocalin identifies spontaneous bacterial peritonitis and predicts mortality in hospitalized patients with cirrhosis[J].Dig Dis Sci, 2017, 62 (12) :3487-3494.
    [18]TANG NY, CHEN WQ.Significance of lipopolysaccharide binding protein in serum and ascites of patients with hepatic cirrhosis complicated with spontaneous bacterial peritonitis[J].Chin JHepatol, 2012, 20 (7) :492-496. (in Chinese) 唐能源, 陈伟庆.血清及腹水脂多糖结合蛋白检测在肝硬化自发性细菌性腹膜炎诊断中的意义[J].中华肝脏病杂志, 2012, 20 (7) :492-496.
    [19]BRUNS T, REUKEN PA, STENGEL S, et al.The prognostic significance of bacterial DNA in patients with decompensated cirrhosis and suspected infection[J].Liver Int, 2016, 36 (8) :1133-1142.
    [20]DEVANI K, CHARILAOU P, JAISWAL P, et al.Trends in hospitalization, acute kidney injury, and mortality in patients with spontaneous bacterial peritonitis[J].J Clin Gastroenterol, 2019, 53 (2) :e68-e74.
    [21]FERNNDEZ J, NAVASA M, PLANAS R, et al.Primary prophylaxis of spontaneous bacterial peritonitis delays hepatorenal syndrome and improves survival in cirrhosis[J].Gastroenterology, 2007, 133 (3) :818-824.
    [22]LOOMBA R, WESLEY R, BAIN A, et al.Role of fluoroquinolones in the primary prophylaxis of spontaneous bacterial peritonitis:Meta-analysis[J].Clin Gastroenterol Hepatol, 2009, 7 (4) :487-493.
    [23]MIN YW, LIM KS, MIN BH, et al.Proton pump inhibitor use significantly increases the risk of spontaneous bacterial peritonitis in 1965 patients with cirrhosis and ascites:A propensity scores matched cohort study[J].Aliment Pharmacol Ther, 2014, 40 (6) :695-704.
    [24]PANDE C, KUMAR A, SARIN SK.Addition of probiotics to norfloxacin does not improve efficacy in the prevention of spontaneous bacterial peritonitis[J].Eur J Gastroenterol Hepatol, 2012, 24 (7) :831-839.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (1388) PDF downloads(319) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return