Expert recommendations on standardized diagnosis and treatment for fatty liver disease (2019 revised edition)

Nonalcoholic fatty liver disease( NAFLD) is the most common liver disease in China. To provide evidence-based and updated practical recommendations for clinician,this expert recommendations have updated the diagnosis and treatment of NAFLD in five aspects as follows:( 1) the framework of NAFLD treatment centre or clinic;( 2) screening and evaluation: who should be screened,initial evaluation items,non-invasive assessment of steatohepatitis and advanced fibrosis,when to obtain a liver biopsy in patients with NAFLD,and other metabolic disorders and cardiovascular risk assessment;( 3) managements of patient with NAFLD: lifestyle intervention( dietary,exercise and weight loss),drug treating metabolic co-morbidities such as hyperlipidemia,type 2 diabetes mellitus and hypertension,and steatohepatitis and fibrosis;( 4) management of special populations with NAFLD: children,pregnant or lactating women,patients co-existence with alcoholic liver disease,chronic HBV and/or HCV infection,and autoimmune disorders;( 5) monitoring and follow-up. This consensus aims to modify the optimizing management process and guide physicians make correct and reasonable decisions in the diagnosis and treatment for patients with NAFLD.