中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 36 Issue 4
Apr.  2020
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Article Contents

STAT3: A key molecule in the progression of liver cancer mediated by chronic inflammation

DOI: 10.3969/j.issn.1001-5256.2020.04.054
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  • Published Date: 2020-04-20
  • STAT3,a member of the signal transducer and activator of transcription family,is abnormally activated in chronic inflammation-related tumors including liver cancer. As a key signal molecule in the microenvironment of liver cancer and inflammation,STAT3 not only participates in the inflammation-cancer transformation during the development of liver cancer,but also promotes the proliferation,invasion,and metastasis of hepatoma cells through many ways,and therefore,it may be a potential target for the treatment of liver cancer. This article reviews the recent advances in the association between STAT3 and liver cancer.

     

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