Hepatic fat content is an important index for the early diagnosis,disease grading,and outcome evaluation of nonalcoholic fatty liver disease( NAFLD). Various magnetic resonance imaging( MRI) methods have been used to determine hepatic fat content in NAFLD,among which proton density fat fraction obtained by magnetic resonance spectroscopy and chemical-shift-encoded MRI can achieve precise quantification of hepatic fat and therefore,it is considered the imaging gold standard for the diagnosis of fatty liver disease and has been applied in clinical research. This article reviews the research advances in the MRI techniques for quantification of hepatic fat content,in order to provide a reference for clinical application and experiment.
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