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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 36 Issue 6
Jun.  2020
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Article Contents

Association between sarcopenia and hepatic encephalopathy and advances in diagnosis and treatment

DOI: 10.3969/j.issn.1001-5256.2020.06.049
  • Published Date: 2020-06-20
  • Sarcopenia is a component of malnutrition in patients with liver cirrhosis. Studies have shown that both sarcopenia and hepatic encephalopathy can reduce quality of life and increase the risk of adverse events,including death,in patients with liver cirrhosis. This article reviews the association between sarcopenia and hepatic encephalopathy and the advances in treatment,so as to provide a reliable basis for the treatment of patients with sarcopenia and liver cirrhosis,prevent the development of hepatic encephalopathy,and thereby improve the quality of life and prolong the survival time of patients with liver disease.

     

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  • [1] SOUTO PA,MARCOTEGUI AR,ORBEA L,et al. Hepatic encephalopathy:Ever closer to its big bang[J]. World J Gastroenterol,2016,22(42):9251-9256.
    [2] CAI JX,LOU HL. Sarcopenia[J/CD]. Electr J of Metab Nutrit Cancer,2019,6(1):135-143.(in Chinese)蔡君香,楼慧玲.肌肉减少症[J/CD].肿瘤代谢与营养电子杂志,2019,6(1):135-143.
    [3] CRUZ-JENTOFT AJ,BAHAT G,BAUER J,et al. Sarcopenia:Revised European consensus on definition and diagnosis[J]. Age Ageing,2019,48(1):16-31.
    [4] CAO P,YAO J,ZHU N,et al. Sarcopenia as an assessment of nutritional status and its risk factors in patients with hepatic cirrhosis[J]. Chin Remed Clin,2017,17(12):1737-1740.(in Chinese)曹平,姚佳,朱娜,等.肌肉减少症评价肝硬化患者营养状况及其影响因素[J].中国药物与临床,2017,17(12):1737-1739.
    [5] QI Q,WU BW,FEI XY. Research progress of influencing factors of cancer-related sarcopenia[J]. Chin Gen Pract,2018,21(15):1769-1774.(in Chinese)戚倩,吴蓓雯,费晓燕.肿瘤相关性肌肉减少症影响因素的研究进展[J].中国全科医学,2018,21(15):1769-1774.
    [6] KIM HY,JANG JW. Sarcopenia in the prognosis of cirrhosis:Going beyond the MELD score[J]. World J Gastroenterol,2015,21(25):7637-7647.
    [7] LI YQ,ZHANG AQ,CAO P,et al. Predictive value of the third lumbar skeletal muscle mass index on prognosis of patients with cirrhosis and ascites[J]. Chin J Hepatol,2019,27(10):806-808.(in Chinese)李玉琴,张爱青,曹平,等.第三腰椎骨骼肌质量指数对肝硬化腹水患者预后的预测价值[J].中华肝脏病杂志,2019,27(10):806-808.
    [8] MITSIOPOULOS N,BAUMGARTNER RN,HEYMSFIELD SB,et al. Cadaver validation of skeletal muscle measurement by magnetic resonance imaging and computerized tomography[J]. J Appl Physiol(1985),1998,85(1):115-122.
    [9] ZHUANG W,ZHANG MM. Definition and diagnostic criteria of myopenia[J/CD]. Electr J of Metab Nutrit Cancer,2014,1(3):1-4.(in Chinese)庄文,张明鸣.肌肉减少症的定义和诊断标准[J/CD].肿瘤代谢与营养电子杂志,2014,1(3):1-4.
    [10] LU YM,CHEN QP. The diagnosis and therapy of sarcopenia[J/CD]. Chin J Clinicians(Electronic Edition),2014,8(24):4454-4457.(in Chinese)卢艳敏,陈强谱.肌肉减少症的诊断及治疗[J/CD].中华临床医师杂志(电子版),2014,8(24):4454-4457.
    [11] MARCELL TJ. Sarcopenia:Causes,consequences,and preventions[J]. J Gerontol A Biol Sci Med Sci,2003,58(10):m911-m916.
    [12] Chinese Society of Hepatology,Chinese Medical Association.Guidelines on the management of hepatic encephalopathy in cirrhosis[J]. J Clin Hepatol,2018,34(10):2076-2089.(in Chinese)中华医学会肝病分学会.肝硬化肝性脑病诊疗指南[J].临床肝胆病杂志,2018,34(10):2076-2089.
    [13] PATIDAR KR,BAJAJ JS. Covert and overt hepatic encephalopathy:Diagnosis and management[J]. Clin Gastroenterol Hepatol,2015,13(12):2048-2061.
    [14] TANG SH,CHEN H,HAN GH. Association between gut microbiota and hepatic encephalopathy in patients with liver addiction[J]. J Clin Hepatol,2019,35(5):1109-1113.(in Chinese)汤世豪,陈辉,韩国宏.肠道菌群与肝硬化肝性脑病的关系[J].临床肝胆病杂志,2019,35(5):1109-1113.
    [15] ELWIR S,RAHIMI RS. Hepatic encephalopathy:An update on the pathophysiology and therapeutic options[J]. J Clin Transl Hepatol,2017,5(2):142-151.
    [16] REN PP,XIE Q. Treatment and prevention of hepatic encephalopathy targeting muscles[J]. Chin Hepatol,2017,22(3):194-195.(in Chinese)任佩佩,谢青.以肌肉为靶点的肝性脑病治疗和预防[J].肝脏,2017,22(3):194-195.
    [17] ROMEIRO FG,AUGUSTI L. Nutritional assessment in cirrhotic patients with hepatic encephalopathy[J]. World J Hepatol,2015,7(30):2940-2954.
    [18] CHANG KV,CHEN JD,WU WT,et al. Is sarcopenia associated with hepatic encephalopathy in liver cirrhosis? A systematic review and meta-analysis[J]. J Formos Med Assoc,2019,118(4):833-842.
    [19] CHEN HL,WANG Q. Pathogenesis and treatment for alcoholic liver disease with sarcopenia:A review[J]. Chin J Mult Organ Dis Elderly,2018,17(10):784-788.(in Chinese)陈海亮,王琦.酒精性肝病肌肉减少症:发病机制与治疗进展[J].中华老年多器官疾病杂志,2018,17(10):784-788.
    [20] HAN F,HAN T,LIANG J. Assessment and clinical management of sarcopenia in patients with liver grading[J]. J Clin Hepatol,2019,35(4):891-894.(in Chinese)韩芳,韩涛,梁静.肝硬化患者肌少症的评估与临床管理[J].临床肝胆病杂志,2019,35(4):891-894.
    [21] SWAMINATHAN M,ELLUL MA,CROSS TJ. Hepatic encephalopathy:Current challenges and future prospects[J]. Hepat Med,2018,10:1-11.
    [22] YE T,LONG H,LIN CX. Nutrition and exercise management status in patients with cirrhosis[J]. Youjiang Med J,2016,44(2):233-236.(in Chinese)叶婷,龙华,林承雄.肝硬化患者的营养和运动管理状况[J].右江医学,2016,44(2):233-236.
    [23] TAJIRI K,SHIMIZU Y. Branched-chain amino acids in liver diseases[J]. Transl Gastroenterol Hepatol,2018,3:47.
    [24] YU R,SHI Q,LIU L,et al. Relationship of sarcopenia with steatohepatitis and advanced liver fibrosis in non-alcoholic fatty liver disease:A meta-analysis[J]. BMC Gastroenterol,2018,18(1):51.
    [25] DASARATHY S,MERLI M. Sarcopenia from mechanism to diagnosis and treatment in liver disease[J]. J Hepatol,2016,65(6):1232-1244.
    [26] BAJAJ JS. The role of microbiota in hepatic encephalopathy[J]. Gut Microbes,2014,5(3):397-403.
    [27] VIDOT H,BOWEN DG,CAREY S,et al. Aggressive nutrition intervention reduces ascites and frequency of paracentesis in malnourished patients with cirrhosis and ascites[J]. JGH Open,2017,1(3):92-97.
    [28] OHASHI K,ISHIKAWA T,HOSHI A,et al. Relationship between sarcopenia and both physical activity and lifestyle in patients with chronic liver disease[J]. J Clin Med Res,2018,10(12):920-927.
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