Inflammatory bowel disease(IBD) is often accompanied by chronic liver diseases in a variety of situations. Due to the overlapping factors in the pathogenesis of IBD and autoimmune liver diseases including primary sclerosing cholangitis( PSC),primary biliary cholangitis,and autoimmune hepatitis,the co-existence of these diseases is not uncommon,among which PSC with IBD has the highest probability of more than 80%. The probability of IBD with chronic hepatitis B virus(HBV)/hepatitis C virus(HCV) infection is associated with local infection rate,and if the screening for HBV/HCV infection is ignored before the application of immunosuppressive agents,there may be a risk of aggravated HBV/HCV infection or HBV reactivation. Long-term treatment with antibiotics,steroids,and immunosuppressants may cause drug-induced liver injury in patients with IBD. Although IBD patients often have weight loss due to the factors including diarrhea and absorption disorders,these patients may have a higher probability of nonalcoholic fatty liver disease than the general population.
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