中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 36 Issue 7
Jul.  2020
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Article Contents

Mechanism of action of microRNA-27a in the development and progression of liver diseases

DOI: 10.3969/j.issn.1001-5256.2020.07.049
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  • Published Date: 2020-07-20
  • microRNAs( miRNAs) are low-molecular-weight non-coding RNAs that regulate various physiological and pathological functions through the regulation of gene expression at the post-transcriptional level. More and more evidence has shown that microRNA-27 a( miRNA-27 a) plays a role in the development and pathogenesis of liver diseases. By reviewing and updating related studies,this article introduces the research advances in the role of miRNA-27 a in various liver diseases including fatty liver disease,hepatitis,hepatic fibrosis,and liver cancer and analyzes the role of miRNA-27 a in liver regeneration and its potential as a biomarker,so as to provide a reference for future studies and more possibilities for new treatment ideas for chronic hepatic diseases.

     

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