中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 36 Issue 8
Aug.  2020
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Article Contents

Value of programmed cell death ligand 1 and soluble programmed cell death ligand 1 in predicting the prognosis of hepatocellular carcinoma and related controversies

DOI: 10.3969/j.issn.1001-5256.2020.08.039
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  • Published Date: 2020-08-20
  • At present,there are various treatment methods for hepatocellular carcinoma(HCC),including surgical treatment,interventional treatment,and immunotherapy,and even so,the five-year survival rate of HCC patients is only 12.5%.Influencing factors for the prognosis of HCC have always been the focus of research.With the in-depth research on programmed cell death protein 1(PD-1) inhibitors in the treatment of HCC in recent years,the role of programmed cell death ligand 1(PD-L1) and soluble programmed cell death ligand 1(s PD-L1),as the ligands of PD-1,in immune escape and their value in predicting prognosis have attracted more and more attention.This article elaborates on the current controversies,consensus,and advances in PD-L1 and s PD-L1 as immune markers in evaluating the prognosis of HCC.

     

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