中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 36 Issue 8
Aug.  2020
Turn off MathJax
Article Contents

Role of microRNAs in gallbladder carcinoma

DOI: 10.3969/j.issn.1001-5256.2020.08.049
  • Published Date: 2020-08-20
  • MicroRNAs(miRNAs) are endogenous non-coding small molecular RNAs that widely exist in eukaryotes,and mature miRNAs are composed of 20-25 nucleotide sequences.With the deepening of the research on miRNAs in recent years,it has been found that miRNAs play an important role in the development,progression,prognosis,chemotherapy resistance,and early diagnosis of gallbladder carcinoma.This article reviews the research advances in the role of miRNAs in gallbladder carcinoma.

     

  • loading
  • [1] HUNDAL R,SHAFFER EA. Gallbladder cancer:Epidemiology and outcome[J]. Clin Epidemiol,2014,6:99-109.
    [2] CHEN W,ZHENG R,BAADE PD,et al. Cancer statistics in China,2015[J]. CA Cancer J Clin,2016,66(2):115-132.
    [3] ZHANG FB,ZHANG YM. Research advances in the pathogenesis and surgical treatment of gallbladder carcinoma[J].J Clin Hepatol,2018,34(5):1133-1136.(in Chinese)张复波,张雅敏.胆囊癌发病机制及外科治疗的研究进展[J].临床肝胆病杂志,2018,34(5):1133-1136.
    [4] LI JD,XU XF,YU JJ,et al. Updated key points and clinical pathway for NCCN clinical practice guidelines in oncology:Hepatobiliary cancers(Version 1. 2018)[J]. J Clin Hepatol,2018,34(6):966-977.(in Chinese)李居东,徐新飞,余炯杰,等.《2018年美国国立综合癌症网络肝胆肿瘤临床实践指南(V1版)》更新要点及临床路径[J].临床肝胆病杂志,2018,34(6):966-977.
    [5] GOETZE TO. Gallbladder carcinoma:Prognostic factors and therapeutic options[J]. World J Gastroenterol,2015,21(43):12211-12217.
    [6] WANG TG,XUE F,LI Y,et al. Effects of miR-26a targeting HMGA1 gene on growth, invasion and migration of colon cancer cells[J]. J Jilin Univ:Med Edit,2018,44(6):1205-1211.(in Chinese)王廷刚,薛峰,李宇,等.miR-26a靶向HMGA1基因对结肠癌细胞生长、侵袭和迁移的影响[J].吉林大学学报:医学版,2018,44(6):1205-1211.
    [7] RAMALINGAM P,PALANICHAMY JK,SINGH A,et al. Biogenesis of intronic miRNAs located in clusters by independent transcription and alternative splicing[J]. RNA,2014,20(1):76-87.
    [8] NEUDECKER V,BRODSKY KS,KRETH S,et al. Emerging roles for microRNAs in perioperative medicine[J]. Anesthesiology,2016,124(2):489-506.
    [9] QIU Y,LUO X,KAN T,et al. TGF-βupregulates miR-182expression to promote gallbladder cancer metastasis by targeting CADM1[J]. Mol Biosyst,2014,10(3):679-685.
    [10] DERYNCK R,WEINBERG RA. EMT and cancer:More than meets the eye[J]. Dev Cell,2019,49(3):313-316.
    [11] POLIOUDAKI H,AGELAKI S,CHIOTAKI R,et al. Variable expression levels of keratin and vimentin reveal differential EMT status of circulating tumor cells and correlation with clinical characteristics and outcome of patients with metastatic breast cancer[J]. BMC Cancer,2015,15:399.
    [12] HE Z,WU H,ZHENG J. Effects of microRNA-181b-3p on cell invasion and metastasis in gallbladder cancer cells and its mechanisms[J]. J Pract Med,2018,34(23):3874-3878.(in Chinese)何政,吴慧,郑军.microRNA-181b-3p对人胆囊癌细胞侵袭能力的影响[J].实用医学杂志,2018,34(23):3874-3878.
    [13] CHANG Y,LIU C,YANG J,et al. MiR-20a triggers metastasis of gallbladder carcinoma[J]. J Hepatol,2013,59(3):518-527.
    [14] WU S,XIE DL,DAI XY. Down-regulation of miR-155 promotes apoptosis of nasopharyngeal carcinoma CNE-1 cells by targeting PI3K/AKT-FOXO3a signaling[J]. Eur Rev Med Pharmacol Sci,2019,23(17):7391-7398.
    [15] KIA V,PARYAN M,MORTAZAVI Y,et al. Evaluation of exosomal miR-9 and miR-155 targeting PTEN and DUSP14 in highly metastatic breast cancer and their effect on low metastatic cells[J]. J Cell Biochem,2019,120(4):5666-5676.
    [16] WITTEN LW,CHENG CJ,SLACK FJ. miR-155 drives oncogenesis by promoting and cooperating with mutations in the c-Kit oncogene[J]. Oncogene,2019,38(12):2151-2161.
    [17] KONO H,NAKAMURA M,OHTSUKA T,et al. High expression of microRNA-155 is associated with the aggressive malignant behavior of gallbladder carcinoma[J]. Oncol Rep,2013,30(1):17-24.
    [18] ZHANG XL,CHENG JH,QIN CK. MicroRNA-155 expression as a prognostic factor in patients with gallbladder carcinoma after surgical resection[J]. Int J Clin Exp Med,2015,8(11):21241-21246.
    [19] JIN K,XIANG Y,TANG J,et al. miR-34 is associated with poor prognosis of patients with gallbladder cancer through regulating telomere length in tumor stem cells[J]. Tumour Biol,2014,35(2):1503-1510.
    [20] PENG HH,ZHANG YD,GONG LS,et al. Increased expression of microRNA-335 predicts a favorable prognosis in primary gallbladder carcinoma[J]. Onco Targets Ther,2013,6:1625-1630.
    [21] FATIMA N,SRIVASTAVA AN,NIGAM J,et al. Low expression of microRNA335-5p is associated with malignant behavior of gallbladder cancer:A clinicopathological study[J]. Asian Pac J Cancer Prev,2019,20(6):1895-1900.
    [22] ZHOU H,GUO W,ZHAO Y,et al. MicroRNA-135a acts as a putative tumor suppressor by directly targeting very low density lipoprotein receptor in human gallbladder cancer[J]. Cancer Sci,2014,105(8):956-965.
    [23] ZHOU H,GUO W,ZHAO Y,et al. MicroRNA-26a acts as a tumor suppressor inhibiting gallbladder cancer cell proliferation by directly targeting HMGA2[J]. Int J Oncol,2014,44(6):2050-2058.
    [24] CAI J,XU L,CAI Z,et al. MicroRNA-146b-5p inhibits the growth of gallbladder carcinoma by targeting epidermal growth factor receptor[J]. Mol Med Rep,2015,12(1):1549-1555.
    [25] LV YP,SHI W,LIU HX,et al. Identification of miR-146b-5p in tissues as a novel biomarker for prognosis of gallbladder carcinoma[J]. Eur Rev Med Pharmacol Sci,2017,21(3):518-522.
    [26] ZHAO JL,LI GD,LIU M. Advanced in the relation between long-chain non-coding RNA CCAT1 and digestive system malignancies[J]. Pract Oncol J,2019,33(4):367-370.(in Chinese)赵金璐,李国东,刘明.长链非编码RNA CCAT1与消化系统恶性肿瘤关系的研究进展[J].实用肿瘤学杂志,2019,33(4):367-370.
    [27] MA MZ,CHU BF,ZHANG Y,et al. Long non-coding RNA CCAT1 promotes gallbladder cancer development via negative modulation of miRNA-218-5p[J]. Cell Death Dis,2015,6:e1583.
    [28] GOEPPERT B,TRUCKENMUELLER F,ORI A,et al. Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p[J]. Sci Rep,2019,9(1):4796.
    [29] CHEN J,YU Y,CHEN X,et al. MiR-139-5p is associated with poor prognosis and regulates glycolysis by repressing PKM2 in gallbladder carcinoma[J]. Cell Prolif,2018,51(6):e12510.
    [30] POLESZCZUK J,HAHNFELDT P,ENDERLING H. Therapeutic implications from sensitivity analysis of tumor angiogenesis models[J]. PLo S One,2015,10(3):e0120007.
    [31] JIN YP,HU YP,WU XS,et al. miR-143-3p targeting of ITGA6 suppresses tumour growth and angiogenesis by downregulating PLGF expression via the PI3K/AKT pathway in gallbladder carcinoma[J]. Cell Death Dis,2018,9(2):182.
    [32] SHU YJ,BAO RF,JIANG L,et al. MicroRNA-29c-5p suppresses gallbladder carcinoma progression by directly targeting CPEB4 and inhibiting the MAPK pathway[J]. Cell Death Differ,2017,24(3):445-457.
    [33] LU K,FENG F,YANG Y,et al. High-throughput screening identified miR-7-2-3p and miR-29c-3p as metastasis suppressors in gallbladder carcinoma[J]. J Gastroenterol,2020,55(1):51-66.
    [34] CHAN CK,AIMAGAMBETOVA G,UKYBASSOVA T,et al.Human papillomavirus infection and cervical cancer:Epidemiology,screening,and vaccination-review of current perspectives[J]. J Oncol,2019,2019:3257939.
    [35] ZHANG M,GONG W,ZUO B,et al. The microRNA miR-33a suppresses IL-6-induced tumor progression by binding Twist in gallbladder cancer[J]. Oncotarget,2016,7(48):78640-78652.
    [36] YANG D,ZHAN M,CHEN T,et al. miR-125b-5p enhances chemotherapy sensitivity to cisplatin by down-regulating Bcl2in gallbladder cancer[J]. Sci Rep,2017,7:43109.
    [37] LI M,CHEN W,ZHANG H,et al. MiR-31 regulates the cisplatin resistance by targeting Src in gallbladder cancer[J]. Oncotarget,2016,7(50):83060-83070.
    [38] LETELIER P,GARCA P,LEAL P,et al. miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer[J]. Int J Clin Exp Pathol,2014,7(5):1849-1867.
    [39] ZHAN M,ZHAO X,WANG H,et al. miR-145 sensitizes gallbladder cancer to cisplatin by regulating multidrug resistance associated protein 1[J]. Tumour Biol,2016,37(8):10553-10562.
    [40] MITCHELL PS,PARKIN RK,KROH EM,et al. Circulating microRNAs as stable blood-based markers for cancer detection[J].Proc Natl Acad Sci U S A,2008,105(30):10513-10518.
    [41] ZHOU Q,LIU J,QUAN J,et al. MicroRNAs as potential biomarkers for the diagnosis of glioma:A systematic review and meta-analysis[J]. Cancer Sci,2018,109(9):2651-2659.
    [42] LI G,PU Y. MicroRNA signatures in total peripheral blood of gallbladder cancer patients[J]. Tumour Biol,2015,36(9):6985-6990.
    [43] YANG HF,NIU ZP,FENG XX. Significance of joint detection of serum miR-182 and CA153 in diagnosis of gallbladder carcinoma[J]. J Trop Med,2019,19(6):758-761.(in Chinese)杨会锋,牛志鹏,冯新献.血清miR-182与CA153联合检测在胆囊癌诊断中的意义[J].热带医学杂志,2019,19(6):758-761.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (822) PDF downloads(140) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return