How to determine the optimal treatment timing in chronic HBV infection patients with normal ALT and positive HBeAg?

Hong ZHAO; Wen XIE

doi:10.3969/j.issn.1001-5256.2021.06.012

Volume 37 Issue 6

Jun. 2021

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Article Navigation > Journal of Clinical Hepatology > 2021 > 37(6): 1281-1281

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How to determine the optimal treatment timing in chronic HBV infection patients with normal ALT and positive HBeAg?

DOI: 10.3969/j.issn.1001-5256.2021.06.012

Hong ZHAO,
Wen XIE^,

Liver Disease Center, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China

Received Date: 2021-03-31
Accepted Date: 2021-03-31
Published Date: 2021-06-20

Abstract

- Hepatitis B Virus,
- Hepatitis B, Chronic,
- Immune Tolerance,
- Therapeutics

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References

[1]	CHEN CJ, YANG HI, SU J, et al. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level[J]. JAMA, 2006, 295(1): 65-73. DOI: 10.1001/jama.295.1.65.
[2]	KIM GA, LIM YS, HAN S, et al. High risk of hepatocellular carcinoma and death in patients with immune-tolerant-phase chronic hepatitis B[J]. Gut, 2018, 67(5): 945-952. DOI: 10.1136/gutjnl-2017-314904.
[3]	LEE HW, KIM EH, LEE J, et al. Natural history of untreated HBeAg-positive chronic HBV infection with persistently elevated HBV DNA but normal alanine aminotransferase[J]. Clin Transl Gastroenterol, 2020, 11(3): e00140. DOI: 10.14309/ctg.0000000000000140.
[4]	CHANG Y, CHOE WH, SINN DH, et al. Nucleos(t)ide analogue treatment for patients with hepatitis B virus (HBV) e antigen-positive chronic HBV genotype C infection: A nationwide, multicenter, retrospective study[J]. J Infect Dis, 2017, 216(11): 1407-1414. DOI: 10.1093/infdis/jix506.

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How to determine the optimal treatment timing in chronic HBV infection patients with normal ALT and positive HBeAg?

DOI: 10.3969/j.issn.1001-5256.2021.06.012

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How to determine the optimal treatment timing in chronic HBV infection patients with normal ALT and positive HBeAg?

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