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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 38 Issue 1
Jan.  2022
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Article Contents

Research advances in interferon-stimulated genes in treatment of hepatitis B virus infection

DOI: 10.3969/j.issn.1001-5256.2022.01.031
Research funding:

Sun Yat-Sen University Clinical Research 5010 Program (2018009)

  • Received Date: 2021-06-04
  • Accepted Date: 2021-06-21
  • Published Date: 2022-01-20
  • Hepatitis B virus (HBV) infection is closely associated with the adverse events such as liver cirrhosis, liver cancer, and liver failure and remains a serious threat to human health. Pegylated interferon is an indispensable drug for the treatment of chronic hepatitis B (CHB), and interferon-stimulated genes are associated with a variety of viruses, but few studies have mentioned their association with hepatitis B and their predictive effect after the treatment of hepatitis B with interferon. This article introduces the predictive factors for interferon treatment of CHB and summarizes the association of interferon-stimulated genes with hepatitis B and their predictive effect, so as to provide a reference for clinical work and basic research.

     

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