Research advances in the mechanism of action of TRPV4 ion channel protein in liver diseases

Laying ZHANG; Mingkai CHEN

doi:10.3969/j.issn.1001-5256.2022.01.040

Volume 38 Issue 1

Jan. 2022

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Article Navigation > Journal of Clinical Hepatology > 2022 > 38(1): 224-227

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Research advances in the mechanism of action of TRPV4 ion channel protein in liver diseases

DOI: 10.3969/j.issn.1001-5256.2022.01.040

Laying ZHANG,
Mingkai CHEN^,

Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, China

Research funding:

The Key Project of Hubei Province (2020BCB007)

Received Date: 2021-05-30
Accepted Date: 2021-07-12
Published Date: 2022-01-20

Abstract

Abstract

As a member of the transient receptor potential ion channel family, transient receptor potential vanilloid 4 (TRPV4) is a non-selective cation channel and is widely distributed in a variety of tissues and organs. In recent years, more and more studies have shown that TRPV4 channel proteins are closely associated with liver diseases such as liver fibrosis, liver cancer, and polycystic liver disease. This article analyzes the articles on TRPV4 and liver disease and summarizes the exact signaling pathways and possible potential mechanism between TRPV4 and liver disease, so as to provide new ideas for clinical application and further studies.
- Liver Diseases,
- Transient Receptor Potential Vanilloid 4,
- Transient Receptor Potential Channels

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References(48)

References

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Research advances in the mechanism of action of TRPV4 ion channel protein in liver diseases

DOI: 10.3969/j.issn.1001-5256.2022.01.040

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Research advances in the mechanism of action of TRPV4 ion channel protein in liver diseases

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