中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 38 Issue 2
Feb.  2022
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Article Contents

Etiology, diagnosis, and treatment of acute liver failure in neonates

DOI: 10.3969/j.issn.1001-5256.2022.02.002
Research funding:

National Natural Science Foundation of China (81671969)

More Information
  • Corresponding author: LI Shuangjie, 2273858951@qq.com
  • Received Date: 2021-12-14
  • Accepted Date: 2022-01-14
  • Published Date: 2022-02-20
  • Neonatal acute liver failure is a rare and life-threatening disease in the neonatal period with complete or substantial loss of liver function, and liver cirrhosis can be identified after birth, with a high mortality rate. The main etiologies of this disease include autoimmune liver diseases during pregnancy, viral infection, blood diseases, metabolic diseases, ischemic injury, and other rare causes. At present, etiological treatment is the main treatment method, and liver transplantation is still an important option for patients with unknown etiology or no response to established treatments. Currently there are few studies on neonatal acute liver failure, so prospective studies are needed to investigate the influencing factors for treatment and prognosis.

     

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