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ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 38 Issue 3
Mar.  2022
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Article Navigation >  Journal of Clinical Hepatology  > 2022  >  38(3): 676-681

Mechanism of action of Huaier granules in treatment of hepatocellular carcinoma and advances in its clinical application

DOI: 10.3969/j.issn.1001-5256.2022.03.038

  • Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, China

Research funding:

Natural Science Foundation of Liaoning Province (20180551193);

Natural Science Foundation of Liaoning Province (2020-MS-181);

345 Talent Project of Shengjing Hospital (40B)

More Information
  • Corresponding author: XU Feng, xufengsjh@126.com(ORCID: 0000-0001-9985-6527)
  • Received Date: 2021-07-30
  • Accepted Date: 2021-10-08
  • Published Date: 2022-03-20
    Abstract
  • Hepatocellular carcinoma (HCC) is the second leading cause of disease-related death in China and greatly threatens the health of residents. Recent studies have shown that traditional Chinese medicine plays an important role in the comprehensive treatment of HCC. Huaier granules have been recommended for the treatment of HCC, and its mechanism of action includes inhibiting angiogenesis, inhibiting the proliferation of HCC cells, inhibiting invasion and metastasis, inducing cell apoptosis, and regulating immune function. This article summarizes the research advances in the anti-HCC mechanism of Huaier granules and its application in clinical practice, in order to provide a reference for subsequent research and clinical treatment.

     

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