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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 38 Issue 8
Aug.  2022
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Article Navigation >  Journal of Clinical Hepatology  > 2022  >  38(8): 1886-1891

Role of traditional Chinese medicine in treatment of chronic hepatitis B by nucleos(t)ide analogues

DOI: 10.3969/j.issn.1001-5256.2022.08.033
  • 1.

    The First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou 450000, China

  • 2.

    Department of Hepatology and Spleen-Stomach, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000, China

Research funding:

National Science and Technology Major Project on Prevention and Treatment of Major Infectious Diseases such as AIDS and Viral Hepatitis (2018ZX10303502)

More Information
  • Corresponding author: ZHAO Wenxia, zhao-wenxia@163.com(ORCID:0000-0001-6549-6754)
  • Received Date: 2021-12-03
  • Accepted Date: 2022-01-13
  • Published Date: 2022-08-20
    Abstract
  • Nucleos(t)ide analogues (NUC) can inhibit the replication of hepatitis B virus (HBV) and effectively treat chronic hepatitis B (CHB), but they cannot completely eradicate HBV and cannot prevent the progression to hepatitis B cirrhosis and liver cancer in the context of a low viral load. In recent years, traditional Chinese medicine has been widely used in the treatment of CHB. This article elaborates on the application and mechanism of traditional Chinese medicine in inhibiting HBV replication, reducing the content of HBeAg, and delaying the progression to hepatitis B cirrhosis, and it is proposed that traditional Chinese medicine can improve the therapeutic effect of NUC in the treatment of CHB.

     

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