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ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 38 Issue 10
Oct.  2022
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Article Navigation >  Journal of Clinical Hepatology  > 2022  >  38(10): 2320-2324

Efficacy of magnetic resonance IDEAL-IQ technique in diagnosis of fat and iron deposition in acute pancreatitis

DOI: 10.3969/j.issn.1001-5256.2022.10.022
  • 1.

    Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region 014040, China

  • 2.

    Department of Medical Radiology, The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region 014010, China

Research funding:

Scientific Research Foundation Project of Baotou Medical College (BYJJ-QM201753)

More Information
  • Corresponding author: LUO Lin, byll117@sina.com(ORCID: 0000-0002-3661-0252)
  • Received Date: 2022-02-07
  • Accepted Date: 2022-03-19
  • Published Date: 2022-10-20
    Abstract
  •   Objective  To perform quantitative evaluation of fat and iron deposition in the pancreas of patients with acute pancreatitis (AP) based on the IDEAL-IQ quantitative parameters fat fraction (FF) and relaxation rate (R2*), and to investigate the efficacy of this technique in the diagnosis of AP.  Methods  A total of 72 patients with AP who were diagnosed and treated in The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology from October 2020 to October 2021, were enrolled as case group, and 82 healthy controls who underwent physical examination during the same period of time were enrolled as control group. The abdominal IDEAL-IQ sequence test was performed for both groups using GE 3.0T magnetic resonance instrument, and FF and R2* values were measured on post-processing workstation. The t-test was used for comparison of normally distributed continuous data between groups, and the Mann-Whitney U test was used for comparison of non-normally distributed continuous data between groups. A receiver operating characteristic (ROC) curve analysis was performed for the parameters with statistical significance, and area under the ROC curve (AUC) was used to evaluate the diagnostic efficacy of parameters.  Results  Compared with the control group, the case group had significantly higher FF value (Z=-10.01, P < 0.001) and R2* value (Z=-3.73, P < 0.001), while there were no significant differences in FF and R2* values between mild AP and moderate-to-severe AP (P > 0.05). FF value had a sensitivity of 100% and a specificity of 90.2% in the diagnosis of AP, while R2* value had a sensitivity of 48.6% and a specificity of 86.6% in the diagnosis of AP.  Conclusion  The quantitative parameter FF value of magnetic resonance IDEAL-IQ technique has relatively high sensitivity and specificity in the diagnosis of AP, and it is a specific index for the diagnosis of AP and holds promise for clinical application.

     

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