[1] |
SUNG H, FERLAY J, SIEGEL RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2021, 71(3): 209-249. DOI: 10.3322/caac.21660.
|
[2] |
ZHOU M, WANG H, ZENG X, et al. Mortality, morbidity, and risk factors in China and its provinces, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017[J]. Lancet, 2019, 394(10204): 1145-1158. DOI: 10.1016/S0140-6736(19)30427-1.
|
[3] |
General Office of National Health Commission. Standard for diagnosis and treatment of primary liver cancer (2022 edition)[J]. J Clin Hepatol, 2022, 38(2): 288-303. DOI: 10.3969/j.issn.1001-5256.2022.02.009.
国家卫生健康委办公厅. 原发性肝癌诊疗指南(2022年版)[J]. 临床肝胆病杂志, 2022, 38(2): 288-303. DOI: 10.3969/j.issn.1001-5256.2022.02.009.
|
[4] |
XIAO J, WANG F, WONG NK, et al. Global liver disease burdens and research trends: Analysis from a Chinese perspective[J]. J Hepatol, 2019, 71(1): 212-221. DOI: 10.1016/j.jhep.2019.03.004.
|
[5] |
BRUIX J, CHAN SL, GALLE PR, et al. Systemic treatment of hepatocellular carcinoma: An EASL position paper[J]. J Hepatol, 2021, 75(4): 960-974. DOI: 10.1016/j.jhep.2021.07.004.
|
[6] |
HEIMBACH JK, KULIK LM, FINN RS, et al. AASLD guidelines for the treatment of hepatocellular carcinoma[J]. Hepatology, 2018, 67(1): 358-380. DOI: 10.1002/hep.29086.
|
[7] |
KUDO M, KAWAMURA Y, HASEGAWA K, et al. Management of hepatocellular carcinoma in Japan: JSH consensus statements and recommendations 2021 update[J]. Liver Cancer, 2021, 10(3): 181-223. DOI: 10.1159/000514174.
|
[8] |
VOGEL A, CERVANTES A, CHAU I, et al. Correction to: "Hepatocellular carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up"[J]. Ann Oncol, 2019, 30(5): 871-873. DOI: 10.1093/annonc/mdy510.
|
[9] |
SHARMA SA, KOWGIER M, HANSEN BE, et al. Toronto HCC risk index: A validated scoring system to predict 10-year risk of HCC in patients with cirrhosis[J]. J Hepatol, 2018, 68(1): 92-99. DOI: 10.1016/j.jhep.2017.07.033.
|
[10] |
ZHANG H, ZHU J, XI L, et al. Validation of the Toronto hepatocellular carcinoma risk index for patients with cirrhosis in China: a retrospective cohort study[J]. World J Surg Oncol, 2019, 17(1): 75. DOI: 10.1186/s12957-019-1619-3.
|
[11] |
YANG HI, YUEN MF, CHAN HL, et al. Risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B): development and validation of a predictive score[J]. Lancet Oncol, 2011, 12(6): 568-574. DOI: 10.1016/S1470-2045(11)70077-8.
|
[12] |
PAPATHEODORIDIS G, DALEKOS G, SYPSA V, et al. PAGE-B predicts the risk of developing hepatocellular carcinoma in Caucasians with chronic hepatitis B on 5-year antiviral therapy[J]. J Hepatol, 2016, 64(4): 800-806. DOI: 10.1016/j.jhep.2015.11.035.
|
[13] |
LEE HW, KIM SU, PARK JY, et al. External validation of the modified PAGE-B score in Asian chronic hepatitis B patients receiving antiviral therapy[J]. Liver Int, 2019, 39(9): 1624-1630. DOI: 10.1111/liv.14129.
|
[14] |
LAMBRECHT J, PORSCH-ÖZÇÜRÜMEZ M, BEST J, et al. The APAC score: a novel and highly performant serological tool for early diagnosis of hepatocellular carcinoma in patients with liver cirrhosis[J]. J Clin Med, 2021, 10(15): 3392. DOI: 10.3390/jcm10153392.
|
[15] |
LI XH, HAO X, DENG YH, et al. The aMAP score was used to assess the risk of liver cancer among people with chronic liver disease in primary hospitals[J]. Chin J Hepatol, 2021, 29(4): 332-337. DOI: 10.3760/cma.j.cn501113-20210329-00144.
李秀华, 郝新, 邓永红, 等. 应用aMAP评分评估基层医院慢性肝病人群的肝癌发生风险[J]. 中华肝脏病杂志, 2021, 29(4): 332-337. DOI: 10.3760/cma.j.cn501113-20210329-00144.
|
[16] |
KIM HY, LAMPERTICO P, NAM JY, et al. An artificial intelligence model to predict hepatocellular carcinoma risk in Korean and Caucasian patients with chronic hepatitis B[J]. J Hepatol, 2022, 76(2): 311-318. DOI: 10.1016/j.jhep.2021.09.025.
|
[17] |
HARRIS PS, HANSEN RM, GRAY ME, et al. Hepatocellular carcinoma surveillance: An evidence-based approach[J]. World J Gastroenterol, 2019, 25(13): 1550-1559. DOI: 10.3748/wjg.v25.i13.1550.
|
[18] |
CHOI J, KIM GA, HAN S, et al. Longitudinal assessment of three serum biomarkers to detect very early-stage hepatocellular carcinoma[J]. Hepatology, 2019, 69(5): 1983-1994. DOI: 10.1002/hep.30233.
|
[19] |
HUGHES DM, BERHANE S, EMILY DE GROOT CA, et al. Serum levels of α-fetoprotein increased more than 10 years before detection of hepatocellular carcinoma[J]. Clin Gastroenterol Hepatol, 2021, 19(1): 162-170. e4. DOI: 10.1016/j.cgh.2020.04.084.
|
[20] |
YAN YF, WANG YT, ZHU C, et al. Meta analysis of the accuracy of liver cancer screening technology[J]. Chin J Evid-Based Med, 2018, 18(5): 418-427. DOI: 10.7507/1672-2531.201802055.
严永锋, 王宇婷, 朱陈, 等. 肝癌筛查技术准确性的Meta分析[J]. 中国循证医学杂志, 2018, 18(5): 418-427. DOI: 10.7507/1672-2531.201802055.
|
[21] |
ROBERTS LR, SIRLIN CB, ZAIEM F, et al. Imaging for the diagnosis of hepatocellular carcinoma: A systematic review and meta-analysis[J]. Hepatology, 2018, 67(1): 401-421. DOI: 10.1002/hep.29487.
|
[22] |
NADAREVIC T, COLLI A, GILJACA V, et al. Magnetic resonance imaging for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease[J]. Cochrane Database Syst Rev, 2022, 5(5): CD014798. DOI: 10.1002/14651858.CD014798.pub2.
|
[23] |
GAO F, WEI Y, ZHANG T, et al. New liver MR imaging hallmarks for small hepatocellular carcinoma screening and diagnosing in high-risk patients[J]. Front Oncol, 2022, 12: 812832. DOI: 10.3389/fonc.2022.812832.
|
[24] |
LV K, ZHAI H, JIANG Y, et al. Prospective assessment of diagnostic efficacy and safety of SonazoidTM and SonoVue® ultrasound contrast agents in patients with focal liver lesions[J]. Abdom Radiol (NY), 2021, 46(10): 4647-4659. DOI: 10.1007/s00261-021-03010-1.
|
[25] |
FRAQUELLI M, NADAREVIC T, COLLI A, et al. Contrast- enhanced ultrasound for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease[J]. Cochrane Database Syst Rev, 2022, 9(9): CD013483. DOI: 10.1002/14651858.CD013483.pub2.
|
[26] |
ZHANG L, GU J, LI Y, et al. Clinical value study on contrast-enhanced ultrasound combined with enhanced CT in early diagnosis of primary hepatic carcinoma[J]. Contrast Media Mol Imaging, 2022, 2022: 7130533. DOI: 10.1155/2022/7130533.
|
[27] |
LIU D, LIU F, XIE X, et al. Accurate prediction of responses to transarterial chemoembolization for patients with hepatocellular carcinoma by using artificial intelligence in contrast-enhanced ultrasound[J]. Eur Radiol, 2020, 30(4): 2365-2376. DOI: 10.1007/s00330-019-06553-6.
|
[28] |
YASAKA K, AKAI H, ABE O, et al. Deep learning with convolutional neural network for differentiation of liver masses at dynamic contrast-enhanced CT: a preliminary study[J]. Radiology, 2018, 286(3): 887-896. DOI: 10.1148/radiol.2017170706.
|
[29] |
HU HT, WANG W, CHEN LD, et al. Artificial intelligence assists identifying malignant versus benign liver lesions using contrast-enhanced ultrasound[J]. J Gastroenterol Hepatol, 2021, 36(10): 2875-2883. DOI: 10.1111/jgh.15522.
|
[30] |
ZHOU JM, WANG T, ZHANG KH. AFP-L3 for the diagnosis of early hepatocellular carcinoma: A meta-analysis[J]. Medicine (Baltimore), 2021, 100(43): e27673. DOI: 10.1097/MD.0000000000027673.
|
[31] |
CHOI J, KIM GA, HAN S, et al. Longitudinal assessment of three serum biomarkers to detect very early-stage hepatocellular carcinoma[J]. Hepatology, 2019, 69(5): 1983-1994. DOI: 10.1002/hep.30233.
|
[32] |
BEST J, BECHMANN LP, SOWA JP, et al. GALAD score detects early hepatocellular carcinoma in an international cohort of patients with nonalcoholic steatohepatitis[J]. Clin Gastroenterol Hepatol, 2020, 18(3): 728-735. e4. DOI: 10.1016/j.cgh.2019.11.012.
|
[33] |
CAVIGLIA GP, CIRUOLO M, ABATE ML, et al. Alpha-fetoprotein, protein induced by vitamin K absence or antagonist ii and glypican-3 for the detection and prediction of hepatocellular carcinoma in patients with cirrhosis of viral Etiology[J]. Cancers (Basel), 2020, 12(11): 3218. DOI: 10.3390/cancers12113218.
|
[34] |
SAMMAN BS, HUSSEIN A, SAMMAN RS, et al. Common sensitive diagnostic and prognostic markers in hepatocellular carcinoma and their clinical significance: a Review[J]. Cureus, 2022, 14(4): e23952. DOI: 10.7759/cureus.23952.
|
[35] |
SHAKER MK, ATTIA FM, HASSAN AA, et al. Evaluation of golgi protein 73 (GP73) as a potential biomarkers for hepatocellular carcinoma[J]. Clin Lab, 2020, 66(8): 190911. DOI: 10.7754/Clin.Lab.2020.190911.
|
[36] |
YAMASHITA T, KOSHIKAWA N, SHIMAKAMI T, et al. Serum laminin γ2 monomer as a diagnostic and predictive biomarker for hepatocellular carcinoma[J]. Hepatology, 2021, 74(2): 760-775. DOI: 10.1002/hep.31758.
|
[37] |
CHEN L, ZHANG H, JIANG B. Diagnostic value of combined detection of serum AFP, GGTI Ⅱ, AFU and DCP in liver cancer[J]. J Mol Diagn Ther, 2022, 14 (8): 1283-1286, 1291. DOI: 10.3969/j.issn.1674-6929.2022.08.006.
陈琳, 张恒, 江斌. 血清AFP、GGTIⅡ、AFU和DCP联合检测对肝癌的诊断价值[J]. 分子诊断与治疗杂志, 2022, 14(8): 1283-1286, 1291. DOI: 10.3969/j.issn.1674-6929.2022.08.006.
|
[38] |
EUN JW, JANG JW, YANG HD, et al. Serum proteins, HMMR, NXPH4, PITX1 and THBS4; a panel of biomarkers for early diagnosis of hepatocellular carcinoma[J]. J Clin Med, 2022, 11(8): 2128. DOI: 10.3390/jcm11082128.
|
[39] |
CHEN L, ABOU-ALFA GK, ZHENG B, et al. Genome-scale profiling of circulating cell-free DNA signatures for early detection of hepatocellular carcinoma in cirrhotic patients[J]. Cell Res, 2021, 31(5): 589-592. DOI: 10.1038/s41422-020-00457-7.
|
[40] |
CHALASANI NP, RAMASUBRAMANIAN TS, BHATTACHARYA A, et al. A novel blood-based panel of methylated dna and protein markers for detection of early-stage hepatocellular carcinoma[J]. Clin Gastroenterol Hepatol, 2021, 19(12): 2597-2605. e4. DOI: 10.1016/j.cgh.2020.08.065.
|
[41] |
ZHOU J, YU L, GAO X, et al. Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma[J]. J Clin Oncol, 2011, 29(36): 4781-4788. DOI: 10.1200/JCO.2011.38.2697.
|
[42] |
LI YS, YANG ZG, CHEN Y, et al. Differential expression profile of cyclic RNA in serum exocrine bodies of hepatocellular carcinoma and its clinical significance[J]. J Hepatopancreatobiliary Surg, 2022, 34(5): 283-287. DOI: 10.11952/j.issn.1007-1954.2022.05.006.
李叶晟, 杨宗国, 陈晹, 等. 肝癌血清外泌体环状RNA表达谱差异及其临床意义[J]. 肝胆胰外科杂志, 2022, 34(5): 283-287. DOI: 10.11952/j.issn.1007-1954.2022.05.006.
|
[43] |
Large scale prospective cohort study data of early screening liquid biopsy for liver cancer[EB/OL]. [2021-09-01].
肝癌早筛液体活检大规模前瞻性队列研究数据[EB/OL]. [2021-09-01].
|
[44] |
LIN N, LIN Y, XU J, et al. A multi-analyte cell-free DNA-based blood test for early detection of hepatocellular carcinoma[J]. Hepatol Commun, 2022, 6(7): 1753-1763. DOI: 10.1002/hep4.1918.
|
[45] |
ZHAN S, YANG P, ZHOU S, et al. Serum mitochondrial tsRNA serves as a novel biomarker for hepatocarcinoma diagnosis[J]. Front Med, 2022, 16(2): 216-226. DOI: 10.1007/s11684-022-0920-7.
|
[46] |
LI Y, LI R, CHENG D, et al. The potential of CircRNA1002 as a biomarker in hepatitis B virus-related hepatocellular carcinoma[J]. Peer J, 2022, 10: e13640. DOI: 10.7717/peerj.13640.
|
[47] |
STEPIEN M, KESKI-RAHKONEN P, KISS A, et al. Metabolic perturbations prior to hepatocellular carcinoma diagnosis: Findings from a prospective observational cohort study[J]. Int J Cancer, 2021, 148(3): 609-625. DOI: 10.1002/ijc.33236.
|
[48] |
WANG SF, BAI ZF, YANG X, et al. Determination of serum metabolic group in patients with hepatocellular carcinoma by UPLC-QTOF-MS/MS technique[J]. Chin J Pharmacol Toxicol, 2020, 34(12): 918-929. DOI: 10.3867/j.issn.1000-3002.2020.12.004.
王淑凤, 柏兆方, 杨馨, 等. 应用UPLC-QTOF-MS/MS技术测定肝细胞癌患者血清代谢组[J]. 中国药理学与毒理学杂志, 2020, 34(12): 918-929. DOI: 10.3867/j.issn.1000-3002.2020.12.004.
|
[49] |
LIU J, GENG W, SUN H, et al. Integrative metabolomic characterisation identifies altered portal vein serum metabolome contributing to human hepatocellular carcinoma[J]. Gut, 2022, 71(6): 1203-1213. DOI: 10.1136/gutjnl-2021-325189.
|
[50] |
YANG T, WANG Y, DAI W, et al. Increased B3GALNT2 in hepatocellular carcinoma promotes macrophage recruitment via reducing acetoacetate secretion and elevating MIF activity[J]. J Hematol Oncol, 2018, 11(1): 50. DOI: 10.1186/s13045-018-0595-3.v
|
[51] |
CONG M, OU X, HUANG J, et al. A predictive model using n-glycan biosignatures for clinical diagnosis of early hepatocellular carcinoma related to hepatitis B virus[J]. OMICS, 2020, 24(7): 415-423. DOI: 10.1089/omi.2020.0055.
|