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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 39 Issue 7
Jul.  2023
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Article Contents

Interpretation of guideline for the prevention and treatment of hepatitis C (2022 version): Antiviral therapy for special populations

DOI: 10.3969/j.issn.1001-5256.2023.07.008
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  • Corresponding author: JI Fanpu, jifanpu1979@163.com(ORCID: 0000-0002-1463-8035)
  • Received Date: 2023-05-15
  • Accepted Date: 2023-06-18
  • Published Date: 2023-07-20
  • In 2022, Chinese Society of Hepatology and Chinese Society of Infectious Diseases, Chinese Medical Association, organized domestic experts to update the guideline for the prevention and treatment of hepatitis C from the aspects of epidemiology, population screening and prevention, laboratory testing, simplification of diagnostic processes and treatment regimens, and antiviral therapy for special populations. This article aims to interpret the treatment of special populations not specifically mentioned in the new guideline, including pregnant women and patients with hepatocellular carcinoma, as well as other issues that need to be solved, in order to provide a reference for clinicians in practical work.

     

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  • [1]
    GOWER E, ESTES C, BLACH S, et al. Global epidemiology and genotype distribution of the hepatitis C virus infection[J]. J Hepatol, 2014, 61(1 Suppl): s45-s57. DOI: 10.1016/j.jhep.2014.07.027.
    [2]
    Polaris Observatory HCV Collaborators. Global change in hepatitis C virus prevalence and cascade of care between 2015 and 2020: a modelling study[J]. Lancet Gastroenterol Hepatol, 2022, 7(5): 396-415. DOI: 10.1016/S2468-1253(21)00472-6.
    [3]
    Chinese Society of Hepatology and Chinese Society of Infectious Diseases, Chinese Medical Association. Guideline for the prevention and treatment of hepatitis C (2022 version)[J]. Chin J Clin Infect Dis, 2022, 15(6): 428-447. DOI: 10.3760/cma.j.issn.1674-2397.2022.06.002.

    中华医学会肝病学分会, 中华医学会感染病学分会. 丙型肝炎防治指南(2022年版)[J]. 中华临床感染病杂志, 2022, 15(6) : 428-447. DOI: 10.3760/cma.j.issn.1674-2397.2022.06.002.
    [4]
    European Association for the Study of the Liver. EASL recommendations on treatment of hepatitis C: Final update of the series☆[J]. J Hepatol, 2020, 73(5): 1170-1218. DOI: 10.1016/j.jhep.2020.08.018.
    [5]
    ZENG QL, ZHANG JY, ZHANG Z, et al. Sofosbuvir and ABT-450: terminator of hepatitis C virus?[J]. World J Gastroenterol, 2013, 19(21): 3199-3206. DOI: 10.3748/wjg.v19.i21.3199.
    [6]
    ZHU SS, ZENG QL, DONG Y, et al. Interferon-α plus ribavirin yields 98% sustained virologic response in children aged 1-5 years with iatrogenic chronic hepatitis C[J]. Hepatol Int, 2015, 9(4): 578-585. DOI: 10.1007/s12072-015-9671-8.
    [7]
    SPERA AM, ELDIN TK, TOSONE G, et al. Antiviral therapy for hepatitis C: Has anything changed for pregnant/lactating women?[J]. World J Hepatol, 2016, 8(12): 557-565. DOI: 10.4254/wjh.v8.i12.557.
    [8]
    ABDALLAH M, ALBORAIE M, ABDEL-RAZEK W, et al. Pregnancy outcome of anti-HCV direct-acting antivirals: Real-life data from an Egyptian cohort[J]. Liver Int, 2021, 41(7): 1494-1497. DOI: 10.1111/liv.14913.
    [9]
    ZENG QL, YU ZJ, LV J, et al. Sofosbuvir-based therapy for late pregnant women and infants with severe chronic hepatitis C: A case series study[J]. J Med Virol, 2022, 94(9): 4548-4553. DOI: 10.1002/jmv.27877.
    [10]
    BHATTACHARYA D, ARONSOHN A, PRICE J, et al. Hepatitis C Guidance 2023 Update: AASLD-IDSA Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection[J]. Clin Infect Dis, 2023. DOI: 10.1093/cid/ciad319.[Online ahead of print]
    [11]
    GAO X, JI FP. Diagnosis and treatment strategies of hepatitis C-related hepatocellular carcinoma in the era of direct-acting antiviral drugs[J]. Chin J Hepatol, 2020, 28(10): 827-830. DOI: 10.3760/cma.j.cn501113-20200914-00516.

    高旭, 纪泛扑. 直接抗病毒药物时代丙型肝炎病毒相关肝细胞癌的诊治对策[J]. 中华肝脏病杂志, 2020, 28 (10): 827-830. DOI: 10.3760/cma.j.cn501113-20200914-00516.
    [12]
    REIG M, CABIBBO G. Antiviral therapy in the palliative setting of HCC (BCLC-B and -C)[J]. J Hepatol, 2021, 74(5): 1225-1233. DOI: 10.1016/j.jhep.2021.01.046.
    [13]
    MOCAN T, NENU I, CRǍCIUN R, et al. Treatment of hepatitis C virus infection in patients with hepatocellular carcinoma: Truth or dare?[J]. J Gastroenterol Hepatol, 2021, 36(6): 1518-1528. DOI: 10.1111/jgh.15376.
    [14]
    WAZIRY R, HAJARIZADEH B, GREBELY J, et al. Hepatocellular carcinoma risk following direct-acting antiviral HCV therapy: A systematic review, meta-analyses, and meta-regression[J]. J Hepatol, 2017, 67(6): 1204-1212. DOI: 10.1016/j.jhep.2017.07.025.
    [15]
    JI F, YEO YH, WEI MT, et al. Sustained virologic response to direct-acting antiviral therapy in patients with chronic hepatitis C and hepatocellular carcinoma: A systematic review and meta-analysis[J]. J Hepatol, 2019, 71(3): 473-485. DOI: 10.1016/j.jhep.2019.04.017.
    [16]
    PRENNER SB, VANWAGNER LB, FLAMM SL, et al. Hepatocellular carcinoma decreases the chance of successful hepatitis C virus therapy with direct-acting antivirals[J]. J Hepatol, 2017, 66(6): 1173-1181. DOI: 10.1016/j.jhep.2017.01.020.
    [17]
    SINGAL AG, RICH NE, MEHTA N, et al. Direct-acting antiviral therapy for hepatitis C virus infection is associated with increased survival in patients with a history of hepatocellular carcinoma[J]. Gastroenterology, 2019, 157(5): 1253-1263. e2. DOI: 10.1053/j.gastro.2019.07.040.
    [18]
    DANG H, YEO YH, YASUDA S, et al. Cure with interferon-free direct-acting antiviral is associated with increased survival in patients with hepatitis C virus-related hepatocellular carcinoma from both East and West[J]. Hepatology, 2020, 71(6): 1910-1922. DOI: 10.1002/hep.30988.
    [19]
    JI F, LI T, NGUYEN MH. Improved survival and high sustained virologic response with DAA therapy in patients with HCV-related HCC: A call for expanded use[J]. J Gastroenterol Hepatol, 2021, 36(6): 1721-1722. DOI: 10.1111/jgh.15420.
    [20]
    KUDO M, FINN RS, QIN S, et al. Overall survival and objective response in advanced unresectable hepatocellular carcinoma: A subanalysis of the REFLECT study[J]. J Hepatol, 2023, 78(1): 133-141. DOI: 10.1016/j.jhep.2022.09.006.
    [21]
    REN Z, QIN S, MENG Z, et al. A phase 2 study of camrelizumab for advanced hepatocellular carcinoma: Two-year outcomes and continued treatment beyond first RECIST-defined progression[J]. Liver Cancer, 2021, 10(5): 500-509. DOI: 10.1159/000516470.
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