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ISSN 2097-3497 (Online)
CN 22-1108/R
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2023 No.7
Theme Issue: Progress in Interventional Diagnosis and Treatment of Portal Hypertension
Chief Editor: ZHU Xiaoli
The First Affiliated Hospital of Soochow University
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Editorial
Clinical application of early transjugular intrahepatic portosystemic shunt and related and research advances
Ze WANG, Jintao HUANG, Binyan ZHONG, Jian SHEN, Xiaoli ZHU
2023, 39(7): 1513-1522. DOI: 10.3969/j.issn.1001-5256.2023.07.001
Abstract(685) HTML (289) PDF (1838KB)(162)
Abstract:
Transjugular intrahepatic portosystemic shunt (TIPS) is a procedure to establish a portosystemic shunt between the hepatic vein and the portal vein via the jugular approach, so as to reduce portal venous pressure and control acute esophagogastric variceal bleeding (EGVB). The prognosis of EGVB has b...
Discussions by Experts
Effect of systemic therapeutic drugs for hepatocellular carcinoma on portal hypertension
Wendi KANG, Yingen LUO, Zhengqiang YANG, Xiao LI
2023, 39(7): 1523-1528. DOI: 10.3969/j.issn.1001-5256.2023.07.002
Abstract(699) HTML (170) PDF (1714KB)(152)
Abstract:
The vast majority of patients with hepatocellular carcinoma (HCC) in China originate from hepatitis B cirrhosis, while 90% of cirrhotic patients may develop portal hypertension, and the HCC patients with portal hypertension account for 15%-30%. Portal hypertension is a group of clinical syndromes ch...
Comparison of endoscopic therapy and TIPS in prophylaxis and treatment of variceal bleeding in decompensated portal hypertension
Mengying LIU, Weizhi LI, Peijie LI, Fuquan MA, Yuling CHEN, Huanhuan SUN, Tiantian GAO, Hui XUE
2023, 39(7): 1529-1534. DOI: 10.3969/j.issn.1001-5256.2023.07.003
Abstract(783) HTML (125) PDF (1720KB)(127)
Abstract:
Esophagogastric variceal bleeding (EGVB) is one of the main complications of decompensated portal hypertension, especially in patients with liver cirrhosis, and it often has a high mortality rate. Medication combined with endoscopy is the main prevention and treatment method for EGVB, while transjug...
Current status and advances in transjugular intrahepatic portosystemic shunt in treatment of refractory ascites due to portal hypertension
Hongliang WANG, Yuelin ZHANG, Kaibing WANG, Tanyang ZHOU, Guanhui ZHOU, Junhui SUN
2023, 39(7): 1535-1540. DOI: 10.3969/j.issn.1001-5256.2023.07.004
Abstract(523) HTML (103) PDF (1715KB)(124)
Abstract:
Refractory ascites is one of the common complications of portal hypertension in decompensated liver cirrhosis and is characterized by extremely poor prognosis and high mortality rate. Transjugular intrahepatic portosystemic shunt (TIPS) is recommended by several international and national guidelines...
Association between transjugular intrahepatic portosystemic shunt and sarcopenia in patients with liver cirrhosis
Bin XIONG, Chongtu YANG
2023, 39(7): 1541-1546. DOI: 10.3969/j.issn.1001-5256.2023.07.005
Abstract(592) HTML (96) PDF (1720KB)(110)
Abstract:
Sarcopenia is a common complication of liver cirrhosis and is significantly associated with poor prognosis. Transjugular intrahepatic portosystemic shunt (TIPS) is an important method for the treatment of portal hypertension and its complications. Based on current studies, this article analyzes the ...
Guideline
Guidelines for the integrated traditional Chinese and Western medicine diagnosis and treatment of acute-on-chronic liver failure
Chinese Association of Integrative Medicine, China Association of Chinese Medicine, Chinese Medical Association
2023, 39(7): 1547-1552. DOI: 10.3969/j.issn.1001-5256.2023.07.006
Abstract(778) HTML (137) PDF (2449KB)(197)
Abstract:
Acute-on-chronic liver failure (ACLF) is a clinical syndrome with the manifestations of liver failure such as acute deepening of jaundice and coagulation disorder due to various predisposing factors, characterized by multiple organ failure and high mortality rate within a short period of time. In te...
Guideline Interpretation
Interpretation of guidelines for the prevention and treatment of chronic hepatitis B (2022 edition)
Yandi XIE, Bo FENG, Huiying RAO
2023, 39(7): 1553-1559. DOI: 10.3969/j.issn.1001-5256.2023.07.007
Abstract(3200) HTML (251) PDF (1733KB)(853)
Abstract:
Guidelines for the prevention and treatment of chronic hepatitis B (2022 edition) are updated and revised based on the research advances in chronic hepatitis B virus infection in China and globally and the previous editions of the guidelines. This article introduces the updates in natural history an...
Interpretation of guideline for the prevention and treatment of hepatitis C (2022 version): Antiviral therapy for special populations
Qinglei ZENG, Fanpu JI
2023, 39(7): 1560-1563. DOI: 10.3969/j.issn.1001-5256.2023.07.008
Abstract(701) HTML (120) PDF (1692KB)(206)
Abstract:
In 2022, Chinese Society of Hepatology and Chinese Society of Infectious Diseases, Chinese Medical Association, organized domestic experts to update the guideline for the prevention and treatment of hepatitis C from the aspects of epidemiology, population screening and prevention, laboratory testing...
Original Article_Viral Hepatitis
Value of blood lipid parameters in predicting the progression of HBV-related acute-on-chronic pre-liver failure
Min GUAN, Jiani LI, Yinjie GAO, Hao LI, Xiaoping WANG, Shanhong TANG
2023, 39(7): 1564-1569. DOI: 10.3969/j.issn.1001-5256.2023.07.009
Abstract(401) HTML (122) PDF (1875KB)(57)
Abstract:
Objective To investigate the difference in blood lipid parameters between acute-on-chronic pre-liver failure (pre-ACLF) and acute-on-chronic liver failure (ACLF) and the risk factors for disease progression. Methods A retrospective analysis was performed for the related data of 118 patients with ACL...
Original Article_Liver fibrosis and liver cirrhosis
Clinical features of idiopathic non-cirrhotic portal hypertension: An analysis of 74 patients
Xinhuan WEI, Jing ZHANG, Zhili ZHANG, Yan LIU, Lijuan FAN, Jian SONG, Yuening ZHANG
2023, 39(7): 1570-1577. DOI: 10.3969/j.issn.1001-5256.2023.07.010
Abstract(417) HTML (112) PDF (2041KB)(62)
Abstract:
Objective Idiopathic non-cirrhotic portal hypertension (INCPH) is a rare cause of portal hypertension, and this study aims to analyze the clinical features of patients with INCPH, and to assist in diagnosis and differential diagnosis. Methods A total of 74 patients who were hospitalized in Beijing Y...
Value of serum chitinase-3-like protein 1 in predicting the risk of decompensation events in patients with liver cirrhosis
Hang YANG, Lili ZHAO, Ping HAN, Qingling CHEN, Jun WEN, Jie LIU, Xiaojing CHENG, Jia LI
2023, 39(7): 1578-1585. DOI: 10.3969/j.issn.1001-5256.2023.07.011
Abstract(799) HTML (332) PDF (2209KB)(56)
Abstract:
Objective To investigate the value of serum chitinase-3-like protein 1 (CHI3L1) in predicting the risk of decompensation events in patients with liver cirrhosis, since prediction of decompensation events and adoption of active preventive measures are the key to improving the survival time of patient...
Original Article_Liver Neoplasm
Risk factors for pulmonary infection after laparoscopic surgery in treatment of hepatocellular carcinoma with liver cirrhosis and portal hypertension
Jing WEN, Zhe JIA, Rong HE, Yanhua ZHANG, Hongwei ZHANG, Ke ZHANG
2023, 39(7): 1586-1591. DOI: 10.3969/j.issn.1001-5256.2023.07.012
Abstract(443) HTML (95) PDF (1876KB)(40)
Abstract:
Objective To investigate the incidence rate of pulmonary infection after laparoscopic surgery and related risk factors in patients with hepatocellular carcinoma (HCC) comorbid with liver cirrhosis and portal hypertension (PHT). Methods A retrospective analysis was performed for the clinical data of ...
Efficacy of hepatic arterial infusion chemotherapy and its multimodality therapeutic regimens in treatment of patients with advanced hepatocellular carcinoma and related prognostic factors
Wencong DAI, Mengya ZANG, Guosheng YUAN, Qi LI, Rong LI, Wenli LI, Shuyu DONG, Jinzhang CHEN
2023, 39(7): 1592-1599. DOI: 10.3969/j.issn.1001-5256.2023.07.013
Abstract(688) HTML (544) PDF (2254KB)(57)
Abstract:
Objective To investigate the efficacy of continuous hepatic arterial infusion chemotherapy (HAIC) with the FOLFOX regimen and its multimodality therapeutic regimen in the treatment of patients with advanced hepatocellular carcinoma, as well as the influencing factors for prognosis. Methods A retrosp...
Value of the nomogram based on HALP score in predicting the prognosis of patients with hepatocellular carcinoma after hepatectomy
Zhuoran LIU, Jing LI, Yu ZHOU, Pingfu XIONG, Li YANG, Wenguang FU
2023, 39(7): 1600-1608. DOI: 10.3969/j.issn.1001-5256.2023.07.014
Abstract(457) HTML (223) PDF (2967KB)(39)
Abstract:
Objective To investigate the value of HALP score in evaluating the prognosis of patients with hepatocellular carcinoma (HCC) after hepatectomy and whether the nomogram based on HALP score could effectively predict the postoperative survival of patients. Methods A retrospective study was performed fo...
Efficacy and safety of microwave ablation combined with systemic chemotherapy in treatment of recurrent intrahepatic cholangiocarcinoma
Chun WEI, Yu LIU, Bo LI, Ou JIANG
2023, 39(7): 1609-1616. DOI: 10.3969/j.issn.1001-5256.2023.07.015
Abstract(469) HTML (134) PDF (2115KB)(30)
Abstract:
Objective To investigate the efficacy and safety of microwave ablation (MWA) combined with chemotherapy versus MWA alone in the treatment of recurrent intrahepatic cholangiocarcinoma (RICC). Methods A retrospective cohort study was conducted among the patients with RICC who received MWA+chemotherapy...
Original Article_Other Liver Disease
Ursolic acid in Hippophae rhamnoides L. inhibits hepatocyte apoptosis in rats with alcoholic liver disease by regulating mitochondria-cytochrome c
Yanhong BAO, Qiang WANG, Wenlong ZHANG, Na GE, Nan LI, Jun SU, Kexin LI
2023, 39(7): 1617-1626. DOI: 10.3969/j.issn.1001-5256.2023.07.016
Abstract(518) HTML (294) PDF (4153KB)(41)
Abstract:
Objective To investigate the inhibitory effect of ursolic acid in Hippophae rhamnoides L. on hepatocyte apoptosis in rats with alcoholic liver disease based on the mitochondria-cytochrome c pathway. Methods A total of 50 specific pathogen-free male Wistar rats were divided into normal control group,...
Analysis of influencing factors on biliary complications after orthotopic liver transplantation
Mingqiang ZHU, Dashuai YANG, Junpeng PEI, Xiangyun XIONG, Yang SU, Youming DING
2023, 39(7): 1627-1632. DOI: 10.3969/j.issn.1001-5256.2023.07.017
Abstract(336) HTML (229) PDF (1878KB)(30)
Abstract:
Objective To analyze the serological markers and surgical indicators associated with biliary complications after orthotopic liver transplantation, explore their influencing factors and predictive indicators. Methods A retrospective analysis was performed for the clinical data of 101 patients who und...
Original Article_Pancreatic Disease
Effect of early thoracic paracentesis drainage on acute lung injury in severe acute pancreatitis
Xuyang WANG, Zhangpeng WANG, Jun WU, Guangxu JING, Zhu HUANG, Hongyu SUN, Lijun TANG
2023, 39(7): 1633-1642. DOI: 10.3969/j.issn.1001-5256.2023.07.018
Abstract(445) HTML (186) PDF (2121KB)(30)
Abstract:
Objective To investigate the effect of early thoracic paracentesis drainage for pleural effusion with a small or moderate volume on acute lung injury in patients with severe acute pancreatitis (SAP). Methods A retrospective analysis was performed for the clinical data of 107 patients with SAP who we...
Influencing factors for acute necrotizing pancreatitis in Eastern and Western countries: A meta-analysis
Shuli MA, Xiaoxi YANG, Chen CHEN, Jing YU, You ZHOU, Guotao LU, Xiaoxing XIANG, Weijuan GONG, Weiwei CHEN, Juan CHEN
2023, 39(7): 1643-1656. DOI: 10.3969/j.issn.1001-5256.2023.07.019
Abstract(471) HTML (160) PDF (2023KB)(29)
Abstract:
Objective To investigate the differences in the influencing factors for acute necrotizing pancreatitis (ANP) and infectious pancreatic necrosis (IPN) between Eastern and Western countries, and to provide a theoretical basis for the prediction and prevention of ANP. Methods Databases including PubMed...
Value of serum interleukin-6 and tumor necrosis factor-α in early diagnosis of severe acute pancreatitis
Jian HE, Sun YU, Jing ZHANG
2023, 39(7): 1657-1664. DOI: 10.3969/j.issn.1001-5256.2023.07.020
Abstract(542) HTML (117) PDF (2570KB)(59)
Abstract:
Objective To investigate the value of serum cytokines in the early diagnosis of severe acute pancreatitis (SAP), and to improve the accuracy of the diagnosis of SAP by establishing a mathematical model with composite indices based on LASSO algorithm. Methods A total of 130 patients with acute pancre...
Brief Report
Clinical and pathological features of drug-induced liver injury with different types of bile duct injury: An analysis of four cases
Tianpeng ZHANG, Lihong YE, Hongxia GAO, Jinhong DONG, Chongkui WANG
2023, 39(7): 1665-1672. DOI: 10.3969/j.issn.1001-5256.2023.07.021
Abstract(463) HTML (210) PDF (2634KB)(62)
Abstract:
Objective To investigate the clinical, biochemical, pathological, disease course, and prognostic features of drug-induced liver injury (DILI) patients with different types of bile duct injury. Methods Four patients who were diagnosed with bile duct injury-type DILI by liver biopsy in Shijiazhuang Fi...
Case Report
Liver transplantation for treating refractory hepatic inflammatory myofibroblastic tumor: A case report
Hongyue XIE, Zheyu ZHOU, Guangxin SHAO, Jiujiu SUN, Xiaoliang XU, Beicheng SUN
2023, 39(7): 1673-1677. DOI: 10.3969/j.issn.1001-5256.2023.07.022
Abstract(439) HTML (132) PDF (2281KB)(49)
Abstract:
Primary atypical epithelioid hemangioendothelioma of the neck of the gallbladder: A case report
Jie YANG, Chengmao XIA, Zhe LIU, Meng ZHU, Yali SHE
2023, 39(7): 1678-1680. DOI: 10.3969/j.issn.1001-5256.2023.07.023
Abstract(351) HTML (106) PDF (4002KB)(45)
Abstract:
Review
Mechanism of action of lipotoxicity in nonalcoholic steatohepatitis
Guoguo ZHI, Jie MU, Bingjie SHAO, Dong WANG
2023, 39(7): 1681-1686. DOI: 10.3969/j.issn.1001-5256.2023.07.024
Abstract(422) HTML (554) PDF (1755KB)(61)
Abstract:
Nonalcoholic steatohepatitis (NASH) is an important part of the exacerbation of nonalcoholic fatty liver disease (NAFLD), and inflammation and liver damage are important pathological features of this stage. As one of the pathogenic mechanisms of NASH, lipotoxicity can regulate liver inflammation and...
Research advances in ferroptosis in the pathogenesis and treatment of nonalcoholic fatty liver disease
Longyun WU, Xiaolan LU
2023, 39(7): 1687-1695. DOI: 10.3969/j.issn.1001-5256.2023.07.025
Abstract(765) HTML (380) PDF (2290KB)(87)
Abstract:
Ferroptosis is a pattern of non-apoptotic cell death characterized by iron dependence and lipid peroxidation. Nonalcoholic fatty liver disease (NAFLD) is a metabolic disease with fat infiltration as its main pathological feature, and it is closely associated with insulin resistance and genetic susce...
Research advances in the role of Enterococcus faecalis in alcoholic liver disease
Boyuan GU, Shengyou XIAO, Chen LIU, Yonglang CHENG, Wenguang FU
2023, 39(7): 1696-1702. DOI: 10.3969/j.issn.1001-5256.2023.07.026
Abstract(479) HTML (406) PDF (1746KB)(41)
Abstract:
Alcoholic liver disease (ALD) is one of the most common chronic liver diseases worldwide and includes the different stages of steatosis, steatohepatitis, fibrosis, and liver cirrhosis. Enterococcus faecalis is a common bacterium for nosocomial infection and has a significant impact on the prognosis ...
Effectiveness of increasing alcohol excise taxes in the management of alcohol-associated liver disease in China
Feiyu ZHANG, Peng XIAO, Yali LIU, Tao LIU, Yanhang GAO
2023, 39(7): 1703-1707. DOI: 10.3969/j.issn.1001-5256.2023.07.027
Abstract(359) HTML (167) PDF (1707KB)(36)
Abstract:
Increasing alcohol excise taxes has been confirmed by the World Health Organization as the most cost-effective public policy for reducing alcohol consumption at the population level. In recent years, studies in foreign countries have believed that increasing alcohol excise taxes can improve the burd...
Role of the nuclear factor erythroid 2-related factor 2/heme oxygenase-1 signaling pathway in alcoholic liver disease
Cheng MA, Hui YANG
2023, 39(7): 1708-1713. DOI: 10.3969/j.issn.1001-5256.2023.07.028
Abstract(787) HTML (1766) PDF (2315KB)(83)
Abstract:
The incidence rate of alcoholic liver disease (ALD) is increasing year by year China, and there is a gradual increase in disease burden among Chinese people. Oxidative stress response in hepatocytes is an important pathogenic mechanism of ALD. The nuclear factor erythroid 2-related factor 2 (Nrf2)/h...
The mechanism of action of partial splenic artery embolization in treatment of liver cirrhosis and hypersplenism
Zongwei LI, Yaqin WANG, Yuewei ZHANG
2023, 39(7): 1714-1720. DOI: 10.3969/j.issn.1001-5256.2023.07.029
Abstract(791) HTML (120) PDF (1732KB)(70)
Abstract:
Hypersplenism is a common complication caused by liver cirrhosis and portal hypertension, and at present, splenectomy and partial splenic artery embolization (PSE) are the main methods for the treatment of hypersplenism. Splenectomy has a marked effect in the treatment of hypersplenism and can signi...
Research advances in rivaroxaban in the treatment of portal vein thrombosis in liver cirrhosis
Shuang LIU, Dongqiang ZHAO
2023, 39(7): 1721-1727. DOI: 10.3969/j.issn.1001-5256.2023.07.030
Abstract(1002) HTML (235) PDF (1882KB)(138)
Abstract:
Portal vein thrombosis (PVT) is one of the common complications of liver cirrhosis and is associated with the poor prognosis of liver disease. Rivaroxaban, a novel direct oral anticoagulant, exerts an antithrombotic effect by directly acting on the active center of factor Xa to inhibit the generatio...
Research advances in brain lactate level and hepatic encephalopathy
Yuqin LIU, Mi CHEN, Lanyan TANG, Lizhi ZHOU, Xin HUANG, Pan ZHANG
2023, 39(7): 1728-1733. DOI: 10.3969/j.issn.1001-5256.2023.07.031
Abstract(394) HTML (186) PDF (2047KB)(32)
Abstract:
Hepatic encephalopathy (HE) is a common complication and an independent risk factor for death in patients with liver cirrhosis. Brain lactate level is associated with the progression and severity of HE, and research on brain lactate level may help to further explain the pathogenesis of HE. This arti...
Role of lipopolysaccharide in the development and progression of liver cancer
Tao WANG, Quan WANG, Lihua SONG, Xuezhang DUAN
2023, 39(7): 1734-1739. DOI: 10.3969/j.issn.1001-5256.2023.07.032
Abstract(491) HTML (235) PDF (2242KB)(85)
Abstract:
Liver cancer is an important public health issue worldwide. With the improvements in high-throughput sequencing and gene editing techniques in recent years, studies have further revealed the biological mechanism of intestinal microflora in the development, progression, and metastasis of liver cancer...
Research advances in transcatheter arterial chemoembolization combined with targeted agents or anti-PD-1/PD-L1 monoclonal antibody in treatment of patients with unresectable hepatocellular carcinoma
Qiuju PENG, Tao DAI, Guibo XIE, Jinjun CHEN, Xiao CHENG, Yuan YAN
2023, 39(7): 1740-1746. DOI: 10.3969/j.issn.1001-5256.2023.07.033
Abstract(442) HTML (133) PDF (1735KB)(49)
Abstract:
Transcatheter arterial chemoembolization (TACE) is recommended by domestic and international guidelines for the treatment of patients with unresectable hepatocellular carcinoma (uHCC), and it is one of the most common treatment methods for patients with uHCC. The chemotherapy drugs commonly used in ...
Role and potential significance of peroxisome proliferator-activated receptors in liver diseases
Shuaixia FENG, Ying XU, Han HAN
2023, 39(7): 1747-1753. DOI: 10.3969/j.issn.1001-5256.2023.07.034
Abstract(1797) HTML (6093) PDF (1940KB)(541)
Abstract:
Peroxisome proliferator-activated receptors (PPAR) are members of the nuclear estrogen receptor family, and they are involved in a variety of physiological and pathological processes in the human body and play important roles in cellular metabolism, inflammation, and cancer. At present, there are th...
Research advances in animal models of cholestatic liver disease
Qingqing ZHANG, Ying QU, Xiaobo CAI, Lungen LU
2023, 39(7): 1754-1760. DOI: 10.3969/j.issn.1001-5256.2023.07.035
Abstract(601) HTML (438) PDF (1728KB)(114)
Abstract:
Cholestatic liver diseases (CLD) are a series of diseases due to impaired bile flow and accumulation of bile acid in the liver and/or systemic circulation caused by immune, genetic, and environmental factors. The pathogenesis of CLD remains unclear and CLD is difficult to treat. As a substitute for ...
Introduction of High-quality Articles in Foreign Journals
Hepatology International｜The effectiveness of combination therapy with interferon and nucleoside analogs in pediatric patients with chronic hepatitis B: a systematic review and meta-analysis
2023, 39(7): 1534-1534. DOI: 10.3969/j.issn.1001-5256.2023.07.gwjpwzjj1
Abstract(242) HTML (115) PDF (750KB)(23)
Abstract:
International Hepatology｜Intracellular labile iron is a key regulator of hepcidin expression and iron metabolism
2023, 39(7): 1686-1686. DOI: 10.3969/j.issn.1001-5256.2023.07.gwjpwzjj2
Abstract(319) HTML (222) PDF (756KB)(12)
Abstract:
Thanks
Current reviewers
2023, 39(7): 1585-1585. DOI: 10.3969/j.issn.1001-5256.2023.7.zhixie1
Abstract(255) HTML (90) PDF (748KB)(12)
Abstract:
    

The first journal specializing in hepatobiliary and pancreatic diseases in China

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