Research advances in the role of <i>Enterococcus faecalis</i> in alcoholic liver disease

Boyuan GU; Shengyou XIAO; Chen LIU; Yonglang CHENG; Wenguang FU

doi:10.3969/j.issn.1001-5256.2023.07.026

Volume 39 Issue 7

Jul. 2023

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Article Navigation > Journal of Clinical Hepatology > 2023 > 39(7): 1696-1702

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Research advances in the role of Enterococcus faecalis in alcoholic liver disease

DOI: 10.3969/j.issn.1001-5256.2023.07.026

a.
Department of General Surgery (Hepatopancreatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China
b.
Academician (Expert) Workstation of Sichuan Province, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China

Research funding:

National Natural Science Foundation of China (82170587);

Luzhou Municipal People's Government-Southwest Medical University Science and Technology Strategic Cooperation Project (2021LZXNYD-Z01)

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Corresponding author: FU Wenguang, fuwg@swmu.edu.cn (ORCID: 0000-0003-3672-9728)
Received Date: 2022-10-16
Accepted Date: 2022-11-28
Published Date: 2023-07-20

Abstract

Abstract

Alcoholic liver disease (ALD) is one of the most common chronic liver diseases worldwide and includes the different stages of steatosis, steatohepatitis, fibrosis, and liver cirrhosis. Enterococcus faecalis is a common bacterium for nosocomial infection and has a significant impact on the prognosis of patients with alcoholic hepatitis. This review mainly introduces the pathogenesis of ALD and the pathogenic mechanism of E. faecalis, summarizes the research advances in E. faecalis in ALD, and briefly describes the detection and treatment methods for E. faecalis infection in clinical practice. Since there is an extremely high mortality rate in ALD patients with lytic E. faecalis infection, an in-depth understanding of E. faecalis has become an important issue nowadays.
- Liver Diseases, Alcoholic,
- Enterococcus faecalis,
- Gastrointestinal Microbiome,
- Intestinal Mucosa

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References(52)

References

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Research advances in the role of Enterococcus faecalis in alcoholic liver disease

DOI: 10.3969/j.issn.1001-5256.2023.07.026

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Research advances in the role of Enterococcus faecalis in alcoholic liver disease

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