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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 39 Issue 8
Aug.  2023
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Article Navigation >  Journal of Clinical Hepatology  > 2023  >  39(8): 1922-1925

Severe hyperbilirubinemia induced by hereditary spherocytosis: A case report

DOI: 10.3969/j.issn.1001-5256.2023.08.023

  • Digestive & Vascular Surgery Center/Department of Liver and Laparoscopic Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

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  • Corresponding author: WEN Hao, dr.wenhao@163.com (ORDIC: 0000-0003-1016-1361)
  • Received Date: 2022-09-19
  • Accepted Date: 2023-02-09
  • Published Date: 2023-08-20
    Abstract
  • Hereditary spherocytosis is a type of hereditary hemolytic disease with human erythrocyte membrane defects and has the main symptoms of anemia, jaundice, and splenomegaly. Since its clinical symptoms are not typical, misdiagnosis or missed diagnosis is often observed. At present, there are rare cases with extremely high levels of total bilirubin and direct bilirubin in clinical practice, with few reports in China and globally. In this study, the patient had a total bilirubin level of 1 686.01 μmol/L and a direct bilirubin level of 1 166.6 μmol/L on admission. The patient was successfully discharged after surgical treatment and had good general conditions and high quality of life during follow-up. This article summarizes the experience in the diagnosis and surgical treatment of hereditary spherocytosis.

     

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