Research advances in human brucellosis vaccines

Jihong AN; Tiantian DU; Zhanguo WANG

doi:10.3969/j.issn.1001-5256.2023.08.037

Volume 39 Issue 8

Aug. 2023

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Article Navigation > Journal of Clinical Hepatology > 2023 > 39(8): 2012-2016

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Research advances in human brucellosis vaccines

DOI: 10.3969/j.issn.1001-5256.2023.08.037

Department of Infectious Diseases, Inner Mongolia Autonomous Region People's Hospital, Hohhot 010000, China

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Corresponding author: WANG Zhanguo, nmgwstwzg@163.com (ORCID: 0009-0001-2389-0769)
Received Date: 2023-05-01
Accepted Date: 2023-06-13
Published Date: 2023-08-20

Abstract

Abstract

Brucellosis is the most common zoonotic disease and a common public health problem worldwide. It not only greatly harms the health of people, but also seriously affects the development of animal husbandry, and it also brings food safety risks. Practice has shown that vaccine immunization is the most effective measure to prevent the epidemic of infectious diseases, and Bifidobacterium abortus vaccine 104M strain is the only vaccine that has been approved for preventing human brucellosis in China. Although the 104M genome of Bifidobacterium abortus has been fully sequenced, genome annotation has not been completed at the moment. In addition, the main mechanisms of residual toxicity and vaccine-induced immune protection have not been clarified. This article mainly elaborates on the clinical manifestations and treatment of brucellosis and related research advances in vaccines.
- Brucella abortus,
- Vaccines, Attenuated,
- Vaccines, Subunit,
- Vaccines, DNA

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References(41)

References

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Research advances in human brucellosis vaccines

DOI: 10.3969/j.issn.1001-5256.2023.08.037

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Research advances in human brucellosis vaccines

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