Diagnostic and treatment strategies for intrahepatic cholangiocarcinoma in special anatomical locations

Hui XUE; Fengwei LI; Kui WANG

doi:10.3969/j.issn.1001-5256.2023.09.003

Volume 39 Issue 9

Sep. 2023

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Article Navigation > Journal of Clinical Hepatology > 2023 > 39(9): 2039-2044

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Diagnostic and treatment strategies for intrahepatic cholangiocarcinoma in special anatomical locations

DOI: 10.3969/j.issn.1001-5256.2023.09.003

Second Department of Hepatic Surgery，The Third Affiliated Hospital of Navy Medical University，Shanghai 200438，China

Research funding:

Clinical Research Plan for SHDC (SHDC2020CR2038B);

Explorer Program of Shanghai Scientific and Technological Committee (21TS1400500);

The “Strong Sea” Innovation Team Program of Naval Military Medical University ;

The Meng Chao Talents Leadership Reserve Training Plan

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Corresponding author: WANG Kui， wangkuiykl@163.com （ORCID： 0000－0002－4935－0533）
Received Date: 2023-07-04
Accepted Date: 2023-08-08
Published Date: 2023-09-19

Abstract

Abstract

The incidence rate of intrahepatic cholangiocarcinoma （ICC） has been increasing significantly in recent years， which has been taken seriously in clinical practice. Compared with hilar and extrahepatic cholangiocarcinoma， ICC tends to have an insidious onset， with clinical symptoms appearing at a later stage. ICC in special anatomical locations often refers to central－type ICC in proximity to major blood vessels and the confluence of bile ducts， namely hilar－type ICC and caudate lobe－type ICC， and such ICC has higher degrees of invasiveness and complexity compared with peripheral－type ICC. At the time of initial diagnosis， most patients with ICC in special anatomical locations do not have the opportunity for radical surgery due to the factors such as insufficient residual liver volume， jaundice， lymph node metastasis， and vascular invasion. With the rapid development of systemic therapy for ICC in recent years， some patients are downstaged after comprehensive therapy and thus obtain the opportunity for radical surgery， but more evidence is still needed to verify the efficacy of such approaches.
- Cholangiocarcinoma,
- Special Anatomical Locations,
- Combined Modality Therapy

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References

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Diagnostic and treatment strategies for intrahepatic cholangiocarcinoma in special anatomical locations

DOI: 10.3969/j.issn.1001-5256.2023.09.003

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Diagnostic and treatment strategies for intrahepatic cholangiocarcinoma in special anatomical locations

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