Human immunodeficiency virus infection comorbid with autoimmune hepatitis－primary biliary cholangitis overlap syndrome： A case report

Shixiu PENG; Chunyan LI; Aiping HUANG; Songtao ZHU; Jing MAI; Liping WU

doi:10.3969/j.issn.1001-5256.2023.09.021

Volume 39 Issue 9

Sep. 2023

Turn off MathJax

Article Contents

Article Navigation > Journal of Clinical Hepatology > 2023 > 39(9): 2175-2178

PDF( 772 KB)

Human immunodeficiency virus infection comorbid with autoimmune hepatitis－primary biliary cholangitis overlap syndrome： A case report

DOI: 10.3969/j.issn.1001-5256.2023.09.021

Shixiu PENG^{1a
,
,
,},
Chunyan LI^2a,
Aiping HUANG^2b,
Songtao ZHU^1b,
Jing MAI^1a,
Liping WU^1a

1a.
Department of Infectious Diseases，Guanghan People’s Hospital，Guanghan，Sichuan 618300，China
1b.
Department of Gastroenterology，Guanghan People’s Hospital，Guanghan，Sichuan 618300，China
2a.
Department of Gastroenterology, The General Hospital of Western Theater Command，Chengdu 610083，China
2b.
Department of Pathology，The General Hospital of Western Theater Command，Chengdu 610083，China

More Information

Corresponding author: PENG Shixiu， 770917530@qq.com （ORCID： 0000－0001－8174－6119）
Received Date: 2023-02-04
Accepted Date: 2023-03-20
Published Date: 2023-09-19

Abstract

Abstract

Acquired immunodeficiency syndrome mainly invades the human immune system and eventually leads to serious defects in human cellular immune function. Autoimmune hepatitis （AIH）－primary biliary cholangitis （PBC） overlap syndrome is a common type of the overlap syndrome of autoimmune liver disease and involves the damage to liver cells and bile capillaries caused by autoimmune dysfunction， while AIH－PBC overlap syndrome comorbid with human immunodeficiency virus （HIV） infection is relatively rare. Guanghan People’s Hospital， in collaboration with The General Hospital of Western Theater Command， reported the diagnosis and treatment of a patient with HIV infection and AIH－PBC overlap syndrome， so as to provide a reference for the clinical diagnosis and treatment of this type of disease.
- HIV Infections,
- Hepatitis， Autoimmune,
- Primary Biliary Cholangitis

FullText(HTML)

References(11)

References

[1]	Acquired Immunodeficiency Syndrome and Hepatitis C Professional Group, Society of Infectious Diseases, Chinese Medical Association; Chinese Center for Disease Control and Prevention. Chinese guidelines for diagnosis and treatment of human immunodeficiency virus infection/acquired immunodeficiency syndrome(2021 edition)[J]. Med J Peking Union Med Coll Hosp, 2022, 13( 2): 203－ 226. DOI: 10.12290/xhyxzz.2022－0097. 中华医学会感染病学分会艾滋病丙型肝炎学组, 中国疾病预防控制中心. 中国艾滋病诊疗指南(2021年版)[J]. 协和医学杂志, 2022, 13( 2): 203－ 226. DOI: 10.12290/xhyxzz.2022－0097.
[2]	WU MC, LI MD. Practice of hepatology[M]. Beijing: People’s Medical Publishing House, 2011: 228. 吴孟超, 李梦东. 实用肝脏病学[M]. 北京: 人民卫生出版社, 2011: 228.
[3]	RUST C, BEUERS U. Overlap syndromes among autoimmune liver diseases[J]. World J Gastroenterol, 2008, 14( 21): 3368－ 3373. DOI: 10.3748/wjg.14.3368.
[4]	XIE J, LI TS. Research progress on abnormal immune activation associated with human immunodeficiency virus infection[J]. Natl Med J China, 2014( 31): 2477－ 2479. DOI: 10.3760/cma.j.issn.0376－2491.2014.31.022. 谢静, 李太生. 人类免疫缺陷病毒感染相关异常免疫激活研究进展[J]. 中华医学杂志, 2014( 31): 2477－ 2479. DOI: 10.3760/cma.j.issn.0376－2491.2014.31.022.
[5]	YAO DK, PENG Y. Current status and prospects of diagnosis and treatment of autoimmune liver diseases[J]. J Southwest Med Univ, 2022, 45( 1): 26－ 28, 43. DOI: 10.3969/j.issn.2096－3351.2022.01.006. 姚定康, 彭宇. 常见自身免疫性肝病的诊治现状与展望[J]. 西南医科大学学报, 2022, 45( 1): 26－ 28, 43. DOI: 10.3969/j.issn.2096－3351.2022.01.006.
[6]	Chinese Society of Hepatology, Chinese Medical Association. Guidelines on the diagnosis and management of autoimmune hepatitis(2021)[J]. J Clin Hepatol, 2022, 38( 1): 42－ 49. 中华医学会肝病学分会. 自身免疫性肝炎诊断和治疗指南(2021)[J]. 临床肝胆病杂志, 2022, 38( 1): 42－ 49.
[7]	CHAZOUILLÈRES O, WENDUM D, SERFATY L, et al. Primary biliary cirrhosis－autoimmune hepatitis overlap syndrome: clinical features and response to therapy[J]. Hepatology, 1998, 28( 2): 296－ 301. DOI: 10.1002/hep.510280203.
[8]	CHEN L, YOU J. Research advances in pathogenesis of HIV infection and acquired immunodeficiency syndrome[J]. Med Recapitulate, 2010, 16( 24): 3713－ 3716. DOI: 10.3969/j.issn.1006－2084.2010.24.012. 陈丽, 游晶. HIV/AIDS发病机制的研究进展[J]. 医学综述, 2010, 16( 24): 3713－ 3716. DOI: 10.3969/j.issn.1006－2084.2010.24.012.
[9]	CHAITEERAKIJ R, SANPAWAT A, AVIHINGSANON A, et al. Autoimmune hepatitis in human immunodeficiency virus－infected patients: A case series and review of the literature[J]. World J Gastroenterol, 2019, 25( 35): 5388－ 5402. DOI: 10.3748/wjg.v25.i35.5388.
[10]	O’LEARY JG, ZACHARY K, MISDRAJI J, et al. De novo autoimmune hepatitis during immune reconstitution in an HIV－infected patient receiving highly active antiretroviral therapy[J]. Clin Infect Dis, 2008, 46( 1): e12－e14. DOI: 10.1086/524082.
[11]	HU ML, WANG QX, MA X. Advances in the pathogenesis of autoimmune hepatitis and new targets for clinical intervention[J]. J Clin Hepatol, 2022, 38( 4): 743－ 747. DOI: 10.3969/j.issn.1001－5256.2022.04.002. 胡明礼, 王绮夏, 马雄. 自身免疫性肝炎发病机制进展与临床干预新靶点[J]. 临床肝胆病杂志, 2022, 38( 4): 743－ 747. DOI: 10.3969/j.issn.1001－5256.2022.04.002.

Relative Articles

Supplements(0)

Cited By

Proportional views

Proportional views

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Figures(1)

Get Citation

PDF

XML

Article Metrics

Article views (368) PDF downloads(54)

Human immunodeficiency virus infection comorbid with autoimmune hepatitis－primary biliary cholangitis overlap syndrome： A case report

DOI: 10.3969/j.issn.1001-5256.2023.09.021

Abstract

References

Proportional views

Catalog

通讯作者: 陈斌, bchen63@163.com

Article Metrics

Proportional views

Related

Human immunodeficiency virus infection comorbid with autoimmune hepatitis－primary biliary cholangitis overlap syndrome： A case report

DOI: 10.3969/j.issn.1001-5256.2023.09.021

Abstract

References

Proportional views

Catalog

通讯作者: 陈斌, bchen63@163.com

Article Metrics

Proportional views

Related

About Journal

Submission Guideline

Journal Online

Hepatobiliary College

Guidelines

Export File

Citation

Format

Content