Role of fecal microbiota transplantation in chronic liver diseases

Hongkai XU; Chunfu WANG; Ye ZHANG; Jianqi LIAN

doi:10.3969/j.issn.1001-5256.2023.09.031

Volume 39 Issue 9

Sep. 2023

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Abstract

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Article Navigation > Journal of Clinical Hepatology > 2023 > 39(9): 2237-2243

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Role of fecal microbiota transplantation in chronic liver diseases

DOI: 10.3969/j.issn.1001-5256.2023.09.031

Department of Infectious Diseases，The Second Affiliated Hospital of Air Force Medical University，Xi’an 710038，China

Research funding:

Shaanxi Province Key Research and Development Plan (2022SF－186)

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Corresponding author: LIAN Jianqi， lianjq@fmmu.edu.cn （ORCID： 0000－0002－5549－7590）
Received Date: 2022-11-21
Accepted Date: 2023-01-02
Published Date: 2023-09-19

Abstract

Abstract

Gut microbiota dysbiosis is closely associated with the development， progression， and prognosis of chronic liver diseases， while chronic liver diseases can aggravate gut microbiota dysbiosis， and the two interact with and influence each other. Through transplantation of fecal flora from healthy donors， fecal microbiota transplantation （FMT） directly reconstructs the intestinal flora of patients and maintains homeostasis， thereby achieving targeted therapeutic outcomes. In recent years， many basic research studies and clinical trials have proved FMT as a core therapeutic strategy for reconstructing intestinal flora and an important breakthrough point in treatment regimens for liver diseases. This article reviews the basic research， clinical studies， and future prospect of FMT in chronic liver diseases.
- Liver Diseases,
- Fecal Microbiota Transplantation,
- Gastrointestinal Microbiome

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References(57)

References

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沈阳化工大学材料科学与工程学院沈阳 110142

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Role of fecal microbiota transplantation in chronic liver diseases

DOI: 10.3969/j.issn.1001-5256.2023.09.031