Recompensation of liver cirrhosis： Current status and challenges

Gong FENG; Juanjuan SONG; Feng YE; Yonghong MA; Yilin REN; Ziyi ZHANG; Na HE; Xueping LI; Man MI

doi:10.3969/j.issn.1001-5256.2023.10.027

Volume 39 Issue 10

Oct. 2023

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Article Navigation > Journal of Clinical Hepatology > 2023 > 39(10): 2464-2469

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Recompensation of liver cirrhosis： Current status and challenges

DOI: 10.3969/j.issn.1001-5256.2023.10.027

Gong FENG^{1a, 2},
Juanjuan SONG^1b,
Feng YE²,
Yonghong MA^1b,
Yilin REN^1c,
Ziyi ZHANG^1d,
Na HE³,
Xueping LI^{1e
,
,
,},
Man MI^{1a
,
,
,}

1a.
Institute of General Practice，Xi’an Medical University，Xi’an 710021，China
1b.
School of Public Health，Xi’an Medical University, Xi’an 710021，China
1c.
School of General Practice，Xi’an Medical University, Xi’an 710021，China
1d.
College of Nursing and Rehabilitation，Xi’an Medical University，Xi’an 710021，China
1e.
School of Clinical Medicine，Xi’an Medical University，Xi’an 710021，China
2.
Department of Infectious Diseases，The First Affiliated Hospital of Xi’an Jiaotong University，Xi’an 710061，China
3.
Department of Gastroenterology，The First Affiliated Hospital of Xi’an Medical University，Xi’an 710077，China

Research funding:

‍2020 Shaanxi Provincial Department of Education project (20JK0343);

Key Scientific Research Project of Inheritance and Innovation of Traditional Chinese Medicine and Development of “Qin Medicine” by Shaanxi Provincial Administration of Traditional Chinese Medicine ;

Research Projects of Xi’an Medical College at University Level in 2021 (2021QN20)

More Information

Corresponding author: LI Xueping，lxp86@163.com （ORCID： 0000－0002－0556－9728）; MI Man，853002274@qq.com （ORCID： 0000－0001－7408－5113）
Received Date: 2023-03-24
Published Date: 2023-10-30

Abstract

Abstract

‍Traditionally， the progression from compensated liver cirrhosis to decompensated liver cirrhosis has been considered an irreversible point in the natural history of the disease； however， with the suppression of underlying etiology， cure， and disease regression， this view is challenged by an increasing number of new evidence， and the idea of “recompensation of liver cirrhosis” is gradually being accepted. In recent years， scholars in China and globally have been exploring the specific definition of recompensation of liver cirrhosis and the clinical features of patients. By summarizing the recent studies on recompensation of liver cirrhosis in China and globally， integrating existing views， and analyzing related research evidence， this article points out the main challenges in the field of recompensation at this stage， including the lack of in－depth clinical and basic research， the need to define recompensation in the context of NAFLD， and related ethical issues， in order to provide new directions for future research in this field.
- Liver Cirrhosis,
- Recompensation,
- Pathological Conditions， Signs and Symptoms

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References(34)

References

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Recompensation of liver cirrhosis： Current status and challenges

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