The incidence and prognosis of non-alcoholic fatty liver disease in primary liver cancer 1293 cases

Liu XiaoYan; Li ShengMian; Yang Jian

Issue 6

Jun. 2010

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Article Navigation > Journal of Clinical Hepatology > 2010 > 26(6): 641-643

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The incidence and prognosis of non-alcoholic fatty liver disease in primary liver cancer 1293 cases

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Published Date: 2010-06-20

Abstract

Abstract

Objective To analyze the clinical data of 1293 primary liver cancer cases and the NAFLD-related primary liver cancer in order to explore the prognosis of primary liver cancer caused by NAFLD retrospectively.Methods The data of primary liver cancer (PHC) cases were assessed and 75 cases of NAFLD were selected.The incidence of NAFLD-related liver cancer and the indicators that may affect the prognosis were analyzed.Results From the 75 NAFLD cases of 5.8% were with PHC and 42 cases PHC with NAFLD died during the follow-up.The overall 1, 2, and 3-year survival rates were 60.55%, 38.63% and 29.53%, respectively.BMI, Type 2 Diabetes, ALT, TBil /DBil, GGT and CHE had an influence on the survival rate (P < 0.05) .BMI was the only independent prognostic factor (χ2 = 5.766, P = 0.016) .Conclusion NAFLD may induce PHC.Obesity and Type 2 Diabetes could be the risk prognostic factors of NAFLD-related hepatocellular carcinoma.Patients with high BMI have poor prognosis.
- fatty liver,
- liver neoplasms,
- risk factors,
- prognosis

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[1]中华医学会.非酒精性脂肪肝性肝病诊断标准[J].中华肝脏病杂志, 2003, 11 (2) ∶71.

[2]Elisabetta B, Nicola L, EsterV, et al.Expanding the natural history of nonalcoholic steatoheptitis:From cryptogenic cirrhosis to hepatocellular careinoma[J].Gastroenterology, 2003, 123 (1) ∶134143.

[3]Hashimoto E, Taniai M, Kaneda H, et al.Comparison of hepatocellular carcinoma patients with alcoholic liver disease and nonalcoholic steatohepatitis[J].Alcohol Clin Exp Res, 2004, 28 (Suppl8) ∶164S-168S.

[4]Yoshioka Y, Hashimoto E, Yatsuji S, et al.Nonalcoholicsteatohepatitis:cirrhosis, hepatocellular carcinoma, and burnt-out NASH[J].Gastroenterol, 2004, 39 (12) ∶1215-1218.

[5]Caldwell SH, Crespo DM, Kang HS, et al.Obesity and hepatocellular carcinoma[J].Gastroenterology, 2004, 127 (5Suppl1) ∶S97103.

[6]Bugianesi E, Leone N, Vanni E, et al.Expanding the natural history of nonalcoholic steatohepatitis:from cryptogenic cirrhosis to hepatocellular carcinoma[J].Gastroenterology, 2002, 123 (1) ∶134140.

[7]Nair S, Mason A, Eason J.Is obesity an independent risk factor for hepatocellular carcinoma in cirrhosis[J].Hepatology, 2002, 36 (1) ∶150-155.

[8]Ipekci SH, Basaranoglu M, Sonsuz A.The fluctuation of serum levels of aminotransferase in patients with nonalcoholic steatohepatitis[J].J Clin Gastroenterol, 2003, 36 (4) ∶371.

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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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The incidence and prognosis of non-alcoholic fatty liver disease in primary liver cancer 1293 cases

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