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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 2
Feb.  2016
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Article Contents

Research advances in methods for determination of tumor boundary in hepatectomy

DOI: 10.3969/j.issn.1001-5256.2016.02.039
Research funding:

 

  • Received Date: 2015-06-12
  • Published Date: 2016-02-20
  • With the in- depth understanding of liver physiology,oncology,and anatomy,as well as the development of imaging technology and surgical equipment,hepatectomy has become more precise. Determination of tumor boundary during surgery has a great significance in realizing precise hepatectomy. Various methods for determination of tumor boundary during hepatectomy have been summarized and compared here,as well as their own advantages and disadvantages,with a focus on the detection methods which have not been widely used in clinical practice but have promising prospects,such as indocyanine green- mediated near- infrared light detection and navigation technique and near- infrared molecular imaging technique mediated by nano- molecular probes. Combined application of various examination techniques will become an inevitable trend of development in liver surgeries in the future.

     

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  • [1]JIA WD.Key techniques in precise hepatectomy for hepatocellular carcinoma[J].Chin J Gen Surg,2014,23(1):1-5.(in Chinese)荚卫东.精准肝切除治疗肝细胞癌关键技术[J].中国普通外科杂志,2014,23(1):1-5.
    [2]DONG JH,TANG MS,ZHANG WZ,et al.Effects of concept and techniques of precision liver surgery on the perioperative safety of patients undergoing major hepatectomy[J].Chin J Digest Surg,2013,12(5):344-351.(in Chinese)董家鸿,唐茂盛,张文智,等.精准肝脏外科理念和技术对大范围肝切除围手术期安全性的影响[J].中华消化外科杂志,2013,12(5):344-351.
    [3]GAO JX,YAO LH.Evaluation of the agreement of preoperative ultrasonography,CT,intraoperative ultrasonography and intraoperative palpation in the diagnosis of liver tumors[J].Chin J Ultrasonogr,2009,18(3):230-233.(in Chinese)高军喜,姚兰辉.术前及术中超声、CT及术中触诊诊断肝肿瘤的一致性评价[J].中华超声影像学杂志,2009,18(3):230-233.
    [4]WU RX,DU Z,ZHAO XM.Application of intraoperative ultrasound in hepatoma surgery[J].Chin J Ultrasonogr,2004,13(6):471-472.(in Chinese)吴荣秀,杜智,赵新民.术中超声在肝肿瘤外科的应用[J].中华超声影像学杂志,2004,13(6):471-472.
    [5]PROCOPIO F,TORZILLI G.Organ targeted mini-invasive approach in the treatment of colorectal cancer liver metastases:role of intraoperative ultrasonography as guidance in liver resection[J].Minerva Chir,2013,68(1):41-47.
    [6]ARAKI K,CONRAD C,OGISO S,et al.Intraoperative ultrasonography of laparoscopic hepatectomy:key technique for safe liver transection[J].J Am Coll Surg,2014,218(2):e37-e41.
    [7]KAWAGUCHI Y,TANAKA N,KOKUDO N.Surgical value of contrast-enhanced ultrasonography in laparoscopic hepatectomy using energy devices[J].J Hepatobiliary Pancreat Sci,2014,21(1):78-79.
    [8]LIU XM,CAO DM,ZHOU QC,et al.Application value of intraoperative ultrasonography in patients of hepatic cirrhosis complicated with carcinoma[J].J Clin Res,2006,23(2):168-170.(in Chinese)刘秀梅,曹丹鸣,周启昌,等.术中超声检查在肝硬化并发肝癌术中的应用[J].医学临床研究,2006,23(2):168-170.
    [9]RUZZENENTE A,CONCI S,IACONO C,et al.Usefulness of contrast-enhanced intraoperative ultrasonography(CE-IOUS)in patients with colorectal liver metastases after preoperative chemotherapy[J].J Gastrointest Surg,2013,17(2):281-287.
    [10]CHEN JX,ZHENG RQ,LI K,et al.Advance researches on imaging evaluation of ablative margin for hepatocellular carcinoma[J].Chin J Med Imaging Technol,2015,31(1):154-157.(in Chinese)陈嘉欣,郑荣琴,李凯,等.影像学评估肝癌消融边界的研究进展[J].中国医学影像技术,2015,31(1):154-157.
    [11]LIN LW,YE Z,XUE ES,et al.Intraoperative ultrasonography in hepatobiliary surgery[J].Hepatobiliary Pancreat Dis Int,2002,1(3):425-428.
    [12]LAU WY,LEUNG KL,LEE TW,et al.Ultrasonography during liver resection for hepatocellular carcinoma[J].Br J Surg,1993,80(4):493-494.
    [13]MACHI J,ISOMOTO H,KUROHIJI T,et al.Accuracy of intraoperative ultrasonography in diagnosing liver metastasis from colorectal cancer:evaluation with postoperative follow-up results[J].World J Surg,1991,15(4):551-556.
    [14]CAI SW,XIE Y,YANG SZ,et al.Application of lasting methylene blue staining in precise hepatectomy[J].Chin J Digest Surg,2010,9(1):28-30.(in Chinese)蔡守旺,谢于,杨世忠,等.持久美蓝染色法在精准肝切除中的应用价值[J].中华消化外科杂志,2010,9(1):28-30.
    [15]CAI SW,YANG SZ,LYU WP,et al.Sustained methylene blue staining to guide anatomic hepatectomy for hepatocellular carcinoma:initial experience and technical details[J].Surgery,2015,158(1):121-127.
    [16]CAI SW,LYU WP,YANG SZ,et al.Application of persistent methylene blue dyeing method for anatomic hepatectomy of hepatocellular carcinoma with bile duct tumor thrombi[J].Chin J Surg,2012,50(6):502-504.(in Chinese)蔡守旺,吕文平,杨世忠,等.持久亚甲蓝染色法在肝细胞癌合并胆管癌栓解剖性肝切除术中的应用[J].中华外科杂志,2012,50(6):502-504.
    [17]ISHIZAWA T,FUKNSHIMA N,SHIBAHARA J,et al.Real-time identification of liver cancers by using indocyanine green fluorescent imaging[J].Cancer,2009,115(11):2491-2504.
    [18]van der VORST JR,SCHAAFSMA BE,HUTTEMAN M,et al.Near infrared fluorescence guided resection of colorectal Liver metastases[J].Cancer,2013,119(18):3411-3418.
    [19]GOTOH K,YAMADA T,ISHIKAWA O,et al.A novel imageguided surgery of hepatocellular carcinoma by indocyanine green fluorescence imaging navigation[J].J Surg Oncol,2009,100(1):75-79.
    [20]KUDO H,ISHIZAWA T,TANI K,et al.Visualization of subcapsular hepatic malignancy by indocyanine-green fluorescence imaging during laparoscopic hepatectomy[J].Surg Endosc,2014,28(8):2504-2508.
    [21]ABO T,NANASHIMA A,TOBINAGA S,et al.Usefulness of intraoperative diagnosis of hepatic tumors located at the liver surface and hepatic segmental visualization using indocyanine green-photodynamic eye imaging[J].Eur J Surg Oncol,2015,41(2):257-264.
    [22]LIM C,VIBERT E,AZOULAY D,et al.Indocyanine green fluorescence imaging in the surgical management of liver cancers:current facts and future implications[J].J Visc Surg,2014,151(2):117-124.
    [23]ISHIZAWA T,ZUKER NB,KOKUDO N,et al.Positive and negative staining of hepatic segments by use of fluorescent imaging techniques during laparoscopic hepatectomy[J].Arch Surg,2012,147(4):393-394.
    [24]ZHAO Q,YAN P,WANG RF,et al.A novel 99mT c-labeled molecular probe for tumor angiogenesis imaging in hepatoma xenografts model:a pilot study[J].PLoS One,2013,8(4):e61043.
    [25]ZHANG J,LU X,WAN N,et al.68Ga-DOTA-NGR as a novel molecular probe for APN-positive tumor imaging using MicroP ET[J].Nucl Med Biol,2014,41(3):268-275.
    [26]SONG JH,YU DX,FANG JJ,et al.Specific MR imaging of hepatocellular carcinoma using AFP-targeted USPIO molecular probe[J].Chin J Hepatobiliary Surg,2012,18(8):618-622.(in Chinese)宋吉慧,于德新,方娟娟,等.甲胎蛋白靶向USPIO分子探针在肝癌特异性磁共振成像中的价值[J].中华肝胆外科杂志,2012,18(8):618-622.
    [27]WANG LL,YU DX,YANG CH,et al.Specific MR imaging of hepatocellular carcinoma with VEGF-C targeted USPIO probe in a rat model[J].J Pract Radiol,2014,30(8):1392-1395.(in Chinese)王琳琳,于德新,杨传红,等.VEGF-C靶向USPIO在大鼠肝癌特异性MR成像中的价值[J].实用放射学杂志,2014,30(8):1392-1395.
    [28]PARK JH,GU L,von MALTZAHN G,et al.Biodegradable luminescent porous silicon nanoparticles for in vivo applications[J].Nat Mater,2009,8(4):331-336.
    [29]CHOI HS,IPE BI,MISRA P,et al.Tissue-and organ-selective biodistribution of NIR fluorescent quantum dots[J].Nano Lett,2009,9(6):2354-2359.
    [30]ZHOU J,SUN Y,DU X,et al.Dual-modality in vivo imaging using rare-earth nanocrystals with near-infrared to near-infrared(NIR-to-NIR)upconversion luminescence and magnetic resonance properties[J].Biomaterials,2010,31(12):3287-3295.
    [31]LI Z,LV S,WANG Y,et al.Construction of LRET-based nanoprobe using upconversion nanoparticles with confined emitters and bared surface as luminophore[J].J Am Chem Soc,2015,137(9):3421-3427.
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