中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 4
Apr.  2017

Clinical effect of hepatectomy versus extracapsular peeling in treatment of hepatic hemangioma

DOI: 10.3969/j.issn.1001-5256.2017.04.020
  • Received Date: 2016-10-26
  • Published Date: 2017-04-20
  • Objective To investigate the clinical effect of hepatectomy versus extracapsular peeling in the treatment of hepatic hemangioma, and to provide a basis for selection of surgical procedure in clinical practice.Methods A retrospective analysis was performed for the clinical data of 115 patients who underwent surgical treatment in The Affiliated Hospital of Xuzhou Medical University from January 2010 to May2016.According to the surgical procedure, these patients were divided into peeling group (79 patients) and hepatectomy group (36 patients) .According to the tumor diameter, the patients were further divided into two subgroups for stratified comparison:89 patients with hepatic hemangioma who had a tumor diameter of 5-10 cm were divided into large peeling group with 64 patients and large hepatectomy group with 25 patients; 26 patients with a tumor diameter of >10 cm were divided into giant hemangioma peeling group with 15 patients and giant hemangioma hepatectomy group with 11 patients.The preoperative, intraoperative, and postoperative clinical data were compared between groups.The two-independent-samples t test was used for comparison of normally distributed continuous data, and the Mann-Whitney U test was used for comparison of non-normally distributed data between groups.The chi-square test and Fisher' s exact test were used for comparison of categorical data between groups.Results There were no significant differences between the hepatectomy group and the peeling group in intraoperative blood loss [300 (200-400) ml vs 300 (225-500) ml, Z=-1.065, P=0.287 ], time of operation [120 (105-160) min vs 140 (95-150) min, Z =-0.036, P = 0.971], postoperative drainage volume [280 (165-520) ml vs 310 (105-546) ml, Z=0.413, P=0.679], length of hospital stay [16 (14-19) d vs 14 (13-19.5) d, Z=-1.283, P=0.200], and hospital costs (27 973.64 ± 10 028.32 RMB vs 28 680.85 ± 10 662.87 RMB, Z=-0.344, P=0.732) .The subgroup analysis showed that there were also no significant differences between the hepatectomy group and the peeling group in intraoperative blood loss, time of operation, postoperative drainage volume, length of hospital stay, and hospital costs (all P>0.05) .Conclusion Hepatectomy and hemangioma peeling have similar clinical effects in the treatment of hepatic hemangioma.

     

  • [1]TORO A, MAHFOUZ AE, ARDIRI A, et al.What is changing in indications and treatment of hepatic hemangiomas.A review[J].Ann Hepatol, 2014, 13 (4) :327-339.
    [2]ZOU H, MA KS.Current situation on radiofrequency ablation of hepatic hemangioma[J].J Clin Hepatol, 2013, 29 (8) :567-569. (in Chinese) 邹华, 马宽生.射频消融治疗肝血管瘤的现状[J].临床肝胆病杂志, 2013, 29 (8) :567-569.
    [3]GIULIANTE F, ARDITO F, VELLONE M, et al.Reappraisal of surgical indications and approach for liver hemangioma:singlecenter experience on 74 patients[J].Am J Surg, 2011, 201 (6) :741-748.
    [4]DONATI M, STAVROU GA, DONATI A, et al.The risk of spontaneous rupuure of liver hemangioma:a critical review of the literature[J].J Gastrointest Surg, 2011, 15 (1) :209-214.
    [5]GAO J, SUN WB.Modern views on surgical treatment of hepatic hemangioma[J].Chin J Med, 2014, 49 (12) :13-15. (in Chinese) 高君, 孙文兵.肝血管瘤外科治疗的现代观[J].中国医刊, 2014, 49 (12) :13-15.
    [6]WU ZB, HUANG ZY.Indications and methods for surgical treatment of hepatic hemangioma[J].J Clin Surg, 2014, 22 (8) :616-618. (in Chinese) 吴珍宝, 黄志勇.肝血管瘤外科治疗的指征与方法[J].临床外科杂志, 2014, 22 (8) :616-618.
    [7]SCHNELLDORFER T, WARE AL, SMOOT R, et al.Management of giant hemangioma of the liver:resection versus observation[J].J Am Coll Surg, 2010, 211 (6) :724-730.
    [8]YEDIBELA S, ALIBEK S, MULLER V, et al.Management of hemangioma of the liver:surgical therapy on observation?[J].World J Surg, 2013, 37 (6) :1303-1312.
    [9]WAGN KY, FU HQ.Surgical treatment and operative indication of hepatic hemangioma[J].Chin J Hepatobiliary Surg, 2011, 17 (9) :701-702. (in Chinese) 王开阳, 傅华群.肝血管瘤的外科治疗现状及手术指征[J].中华肝胆外科杂志, 2011, 17 (9) :701-702.
    [10]DONG J, ZHU Y, WANG WL, et al.Hepatic hemangoma treated by surgical resection:a analysis of 128 patients[J].Chin J Hepatobiliary Surg, 2014, 20 (8) :595-598. (in Chinese) 董建, 朱迎, 王万里, 等.肝血管瘤128例外科治疗分析[J].中华肝胆外科杂志, 2014, 20 (8) :595-598.
    [11]LERNER SM, HIATT JR, SALAMANDRA J, et al.Giant cavernous liver hemangiomas:effect of operative approach on outcome[J].Arch Surg, 2004, 139 (8) :818-821, 821-823.
    [12]CHENG JJ, MA JL.Treatment progress in adult hepatic cavernous hemangioma[J].Med Recapitulate, 2013, 19 (11) :2020-2022. (in Chinese) 程炯炯, 马金良.成人肝海绵状血管瘤的治疗进展[J].医学综述, 2013, 19 (11) :2020-2022.
    [13]DOU KF, JIN C.Prowess in surgery for hemangioma of liver[J].Chin J Dig Surg, 2013, 12 (1) :13-15. (in Chinese) 窦科峰, 金成.肝血管瘤外科治疗进展[J].中华消化外科杂志, 2013, 12 (1) :13-15.
    [14]ZHOU CM, ZHANG JH, REN WX, et al.Treatment and clinical grading system of liver hemangioma among 514 patients[J].Chin J Dig Surg, 2015, 14 (2) :102-105. (in Chinese) 周成明, 张金辉, 任伟新, 等.514例肝血管瘤的治疗与临床评分[J].中华消化外科杂志, 2015, 14 (2) :102-105.
    [15]ZHU Q, QIAO GL, YAN JJ, et al.New perspectives on the natural history and growth pattern of hepatic hemangioma in adults:a cohort study[J].Chin J Hepatobiliary Surg, 2015, 21 (11) :721-725. (in Chinese) 朱倩, 乔国梁, 晏建军, 等.对成人肝血管瘤自然发展进程及生长方式的新认识:队列研究[J].中华肝胆外科杂志, 2015, 21 (11) :721-725.
    [16]GENG XP.Hepatic hemangioma and precise surgical treatment[J].Chin J Bases Clin Gen Surg, 2016, 23 (2) :137-139. (in Chinese) 耿小平.肝血管瘤与精准外科治疗[J].中国普外基础与临床杂志, 2016, 23 (2) :137-139.
    [17]QIU MQ.Comparison of curative effect by resection of hepatic hemangioma and traditional operation of stripping[J].China Med Herald, 2014, 11 (19) :65-68. (in Chinese) 邱明权.肝血管瘤传统手术切除和剥离术疗效对比[J].中国医药导报, 2014, 11 (19) :65-68.
    [18]MUAMMADCUMA DX, WEN H.Advances in surgical diagnosis and treatment of hepatic hemangioma[J].Xinjiang Med J, 2011, 41 (1) :91-95. (in Chinese) 买买提居马·对先, 温浩.肝血管瘤外科诊治进展[J].新疆医学, 2011, 41 (1) :91-95.
    [19]QIN XL, XU J, DI WD, et al.Laparoscopic treatment of hepatic hemangioma on the operation method and curative effect of comparative analysis[J/CD].Chin J Laparoscopic Surgery:Electronic Edition, 2014, 7 (5) :350-353. (in Chinese) 秦学良, 徐钧, 底卫东, 等.腹腔镜治疗肝血管瘤手术方式选择及疗效的比较分析[J/CD].中华腔镜外科杂志:电子版, 2014, 7 (5) :350-353.
    [20]WU X, XIA H, WU J, et al.Clinical experience in treatment of complex intrahepatic bile duct stones by regular hepatectomy[J].J Clin Hepatol, 2016, 32 (9) :1756-1759. (in Chinese) 吴晓, 夏灏, 吴健, 等.规则肝切除术治疗复杂肝内胆管结石的临床体会[J].临床肝胆病杂志, 2016, 32 (9) :1756-1759.
    [21]LI LH, WANG JW, LIU B, et al.Clinical application of three-dimensional reconstruction in preoperative evaluation of hepatectomy[J].J Clin Hepatol, 2016, 32 (5) :938-941. (in Chinese) 李连海, 王建伟, 刘斌, 等.三维重建在肝切除术前评估中的临床应用效果[J].临床肝胆病杂志, 2016, 32 (5) :938-941.
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