2017 No. 4

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Editorial

How to make better use of gastrointestinal endoscopy in diagnosis and treatment of biliary and pancreatic diseases

Zhang ShuTian, Wang YongJun

2017, 33(4): 607-610. DOI: 10.3969/j.issn.1001-5256.2017.04.001

Abstract(1813)

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Abstract:
The techniques for endoscopic diagnosis and treatment of biliary and pancreatic diseases mainly include endoscopic retrograde cholangiopancreatography and endoscopic ultrasonography, which have achieved great progress in recent years. Meanwhile, new techniques including combined therapy with endosco...

Therapeutic guidelines

Guideline for the diagnosis and therapy of gallbladder carcinoma（2016）

Chinese Anti-Cancer Association

2017, 33(4): 611-620. DOI: 10.3969/j.issn.1001-5256.2017.04.002

Abstract(532)

PDF (367KB)(1569) Cited By (67)

Abstract:

An excerpt of AASLD guidelines for the treatment of hepatocellular carcinoma (2016)

Li Jing, Qi XingShun, Han Tao, Li HongYu

2017, 33(4): 621-622. DOI: 10.3969/j.issn.1001-5256.2017.04.003

Abstract(2322)

PDF (1429KB)(516) Cited By (6)

Abstract:

International consensus for the treatment of autoimmune pancreatitis (2016)

Zhao XuDong, Ma YongSu, Yang YinMo

2017, 33(4): 623-626. DOI: 10.3969/j.issn.1001-5256.2017.04.004

Abstract(378)

PDF (224KB)(533) Cited By (18)

Abstract:

An excerpt of pancreatic anastomosis after pancreatoduodenectomy: a position statement by the International Study Group of Pancreatic Surgery (2016)

Hu YaNan, Yang GuiYuan, Qian ZhuYin, Yang XiaoJun

2017, 33(4): 627-631. DOI: 10.3969/j.issn.1001-5256.2017.04.005

Abstract(292)

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Abstract:

An excerpt of ACG clinical guideline: evaluation of abnormal liver chemistries

Yang YaTing, Yan LiTing, Chen Hong, Li JunFeng

2017, 33(4): 632-637. DOI: 10.3969/j.issn.1001-5256.2017.04.006

Abstract(410)

PDF (239KB)(352) Cited By (13)

Abstract:

An excerpt of NASPGHAN clinical practice guideline for the diagnosis and treatment of nonalcoholic fatty liver disease in children

Huang XinYu, Zhang QiuZan

2017, 33(4): 638-642. DOI: 10.3969/j.issn.1001-5256.2017.04.007

Abstract(322)

PDF (241KB)(249) Cited By (1)

Abstract:

Discussions by experts

Laparoscopic hepatectomy: the choice in the era of minimally invasive surgery

Liu Bin, Li WenGang, Chen FuZhen

2017, 33(4): 643-646. DOI: 10.3969/j.issn.1001-5256.2017.04.008

Abstract(2631)

PDF (1464KB)(462) Cited By (13)

Abstract:

Since Reich completed the first laparoscopic hepatectomy ( LH) in 1991, LH has been developed rapidly with the continuous improvement of surgeons' technique and the technological changes in devices and related processes. This article elaborates on the safety and efficacy of LH, the value of 3D visua...

Prevention and treatment of complications after radiofrequency ablation for hepatic tumors in high-risk locations

Song Li, Zou YingHua

2017, 33(4): 647-650. DOI: 10.3969/j.issn.1001-5256.2017.04.009

Abstract(2583)

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Abstract:

Percutaneous radiofrequency ablation ( RFA) has been widely used in the treatment of malignant hepatic tumors and has achieved satisfactory effects. Complications after RFA have been taken seriously and the risk of the development of complications is closely associated with tumor location. It is a g...

Application of combination of various endoscopic techniques in treatment of bile duct stones

Zhang QingKai, Shang Dong

2017, 33(4): 651-655. DOI: 10.3969/j.issn.1001-5256.2017.04.010

Abstract(2406)

PDF (1604KB)(464) Cited By (12)

Abstract:

Bile duct stones are a common disease in clinical practice in China, and due to a high incidence rate of complications and complex causes, its clinical diagnosis and treatment has become a difficult problem which needs to solved urgently. With the development of science and technology and the enhanc...

Features and strategies of endoscopic retrograde cholangiopancreatography in elderly patients aged above 60 years with biliary and pancreatic diseases

Nie ZhanGuo, Dai ZhongMing

2017, 33(4): 656-660. DOI: 10.3969/j.issn.1001-5256.2017.04.011

Abstract(2412)

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Abstract:

Elderly patients with biliary and pancreatic diseases are often complicated by other underlying diseases and have poor cardiopulmonary function, and most of them cannot tolerate general anesthesia. The patients aged above 80 years who have undergone bile duct exploration have high mortality rate and...

Current status of laparoscopic central pancreatectomy

Cao Yang, Liu DaRen, Li JiangTao

2017, 33(4): 661-663. DOI: 10.3969/j.issn.1001-5256.2017.04.012

Abstract(2226)

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Abstract:

Central pancreatectomy is an ideal surgical procedure for the treatment of benign or low-grade malignant tumors in the pancreatic neck or the proximal body of the pancreas, and it can preserve more normal pancreatic tissue in order to reduce the incidence of endocrine and exocrine insufficiency afte...

Original articles_Viral hepatitis

Impact of HBV DNA detection methods on evaluating the clinical effect of PEG-IFNɑ-2b in treatment of HBeAg-positive chronic hepatitis B: a comparative analysis

Guo ChunXia, Li Jia, Xu CengLi, Guo Jie, Zhai Lu, Han Xu

2017, 33(4): 664-667. DOI: 10.3969/j.issn.1001-5256.2017.04.013

Abstract(483)

PDF (193KB)(54) Cited By (5)

Abstract:

Objective To investigate the impact of different HBV DNA detection methods on evaluating the clinical effect of PEG-IFNα-2b in the treatment of HBeAg-positive chronic hepatitis B (CHB) .Methods A total of 83 CHB patients who were admitted to Tianjin Second People's Hospital from September 2014 to Ja...

Construction of HBV whole-genome 1. 3 ploid HepG2 cell model and expression of HBV biomarkers

Qiu Hua, Gao YueQiu, Mao DeWen, Zhou ZhenHua, Long FuLi, Wang MingGang

2017, 33(4): 668-673. DOI: 10.3969/j.issn.1001-5256.2017.04.014

Abstract(2416)

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Abstract:
Objective To construct an HepG2 cell model containing HBV whole-genome 1. 3 ploid ( HBV 1. 3P) , and to investigate the expression of HBV biomarkers. Methods HepG2 cells were transfected with the 1. 3-ploid whole-genome HBV DNA sequence using the adenovirus vector to construct an HBV 1. 3P-HepG2 cel...

Original articles_Liver neoplasms

Clinical features of HBsAg-negative HBV-related hepatocellular carcinoma

Ma Yan, Chen Yan, An LinJing, Qu JianHui, Wang ChunPing, Yang YongPing

2017, 33(4): 674-678. DOI: 10.3969/j.issn.1001-5256.2017.04.015

Abstract(2331)

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Abstract:
Objective To investigate the clinical features of HBsAg-negative HBV-related hepatocellular carcinoma (HCC) .Methods The patients who were newly diagnosed with HCC from January 2005 to January 2012 were enrolled.According to the HBV-related serological markers, the patients were divided into HBsAg-n...

Clinical features of patients developing primary hepatocellular carcinoma during anti-HBV therapy with nucleos (t) ide analogues

Zhang Ying, Liu Ming, Peng XiaoHua, Sun LinLin, Wang YaoHui, Xie ShiBin

2017, 33(4): 679-683. DOI: 10.3969/j.issn.1001-5256.2017.04.016

Abstract(2608)

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Abstract:
Objective To investigate the clinical features of patients developing hepatocellular carcinoma ( HCC) during anti-hepatitis B virus ( HBV) therapy with nucleos ( t) ide analogues ( NAs) . Methods A total of 542 patients who were diagnosed with HCC for the first time in The Third Affiliated Hospital ...

Effect of different minimally invasive therapies on the prognosis of patients with HBV-related primary liver cancer complicated by portal vein tumor thrombus

Li MengGe, Zhao YaLin, Liu XiaoLi, Wang XinHui, Jiang YuYong, Yang ZhiYun

2017, 33(4): 684-688. DOI: 10.3969/j.issn.1001-5256.2017.04.017

Abstract(2152)

PDF (1649KB)(424) Cited By (10)

Abstract:
Objective To investigate the effect of minimally invasive therapy on the 1-year survival of patients with HBV-related primary liver cancer ( PLC) complicated by portal vein tumor thrombus ( PVTT) , and to provide a guidance for clinical treatment. Methods A total of 191 patients who were diagnosed w...

Correlation between microRNA-520a and clinicopathological features of HBV-related hepatocellular carcinoma

Zhang YuRui

2017, 33(4): 689-693. DOI: 10.3969/j.issn.1001-5256.2017.04.018

Abstract(2060)

PDF (1559KB)(396) Cited By (1)

Abstract:
Objective To investigate the correlation between microRNA-520 a and clinicopathological parameters in patients with hepatocellular carcinoma (HCC) .Methods The medical records and tissue specimens of 183 HCC patients, who received surgical treatment in the Affiliated Hospital of Taishan Medical Coll...

Clinical effect of Cyber Knife stereotactic radiosurgery in treatment of patients with small hepatocellular carcinoma

Zhang Tao, Sun Jing, He WeiPing, Li Huan, Wang Hui, Sun YingZhe, Po JunJie, Zhang JunHua, Xu HuiJun, Duan XueZhang

2017, 33(4): 694-698. DOI: 10.3969/j.issn.1001-5256.2017.04.019

Abstract(2401)

PDF (1510KB)(465) Cited By (19)

Abstract:
Objective To investigate the clinical effect and safety of Cyber Knife stereotactic radiosurgery in the treatment of small hepatocellular carcinoma ( s HCC) . Methods Twenty-eight patients with s HCC who underwent Cyber Knife radiosurgery in 302 hospital of PLA form March 2011 to December 2012 were ...

Clinical effect of hepatectomy versus extracapsular peeling in treatment of hepatic hemangioma

Chen Kai, Li XiangNong, Liu Kun, Nan YunGuang, Yang Jun

2017, 33(4): 699-704. DOI: 10.3969/j.issn.1001-5256.2017.04.020

Abstract(2542)

PDF (1481KB)(419) Cited By (4)

Abstract:
Objective To investigate the clinical effect of hepatectomy versus extracapsular peeling in the treatment of hepatic hemangioma, and to provide a basis for selection of surgical procedure in clinical practice.Methods A retrospective analysis was performed for the clinical data of 115 patients who un...

Original articles_Biliary diseases

The most appropriate timing for selective laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage in patients with acute severe cholecystitis aged above 60 years

Zhao HongGuang, Liu Kai, Liu YaHui

2017, 33(4): 705-710. DOI: 10.3969/j.issn.1001-5256.2017.04.021

Abstract(2399)

PDF (1509KB)(450) Cited By (57)

Abstract:
Objective To investigate the clinical effect of selective laparoscopic cholecystectomy (LC) after percutaneous transhepatic gallbladder drainage (PTGD) in the treatment of elderly patients with acute severe cholecystitis, as well as the most appropriate timing for selective operation.Methods A total...

Original articles_Others

A multivariate logistic regression analysis of short-term prognosis of patients with hepatic encephalopathy

Wang FengJiao, Liu MingJiang, Wu RuiHong, Niu JunQi

2017, 33(4): 711-714. DOI: 10.3969/j.issn.1001-5256.2017.04.022

Abstract(2312)

PDF (1477KB)(484) Cited By (16)

Abstract:

Objective To investigate the risk factors for poor short-term prognosis of patients with hepatic encephalopathy (HE) .Methods A retrospective analysis was performed for the clinical data of 316 patients with HE who were hospitalized and treated in The First Hospital of Jilin University from January ...

Clinical effect of plasma perfusion combined with plasma exchange in treatment of patients with acute-on-chronic liver failure

Zhou Jian, Wan Hong, Yang ZhengMao, Wang ZhaoXun

2017, 33(4): 715-718. DOI: 10.3969/j.issn.1001-5256.2017.04.023

Abstract(2251)

PDF (1474KB)(425) Cited By (25)

Abstract:

Objective To investigate the clinical effect of plasma perfusion (PP) combined with plasma exchange (PE) in the treatment of acute-on-chronic liver failure (ACLF) .Methods A total of 72 patients with ACLF who were admitted to The Second People's Hospital of Lanzhou from January 2014 to December 2015...

A risk factors analysis of acute-on-chronic liver failure complicated by spontaneous bacterial peritonitis

Liu ZhengFang, Huang Wei, Li Qin

2017, 33(4): 719-722. DOI: 10.3969/j.issn.1001-5256.2017.04.024

Abstract(2137)

PDF (1480KB)(423) Cited By (10)

Abstract:

Objective To investigate the influencing factors for spontaneous bacterial peritonitis (SBP) in patients with acute-on-chronic liver failure (ACLF) , and to provide a reference for clinical diagnosis and prognosis evaluation.Methods A retrospective analysis was performed for the clinical data of 667...

Brief reports

Clinical effect in joint use of laparoscope and cholecystoscope for treatment of gallbladder and common bile duct stones

Liu JiaNing, Feng Wei, Zhu MeiLing, Lin Bin

2017, 33(4): 723-724. DOI: 10.3969/j.issn.1001-5256.2017.04.025

Abstract(1612)

PDF (1446KB)(382) Cited By (18)

Abstract:

Case reports

Acute hepatitis B complicated by EB virus infection: a case report

Wang HongSha, Wei Qi, Lei ManMan, Jin QingLong, Wen XiaoYu, Guo YuYing

2017, 33(4): 725-727. DOI: 10.3969/j.issn.1001-5256.2017.04.026

Abstract(2044)

PDF (1691KB)(480) Cited By (4)

Abstract:

A case of subacute severe hepatitis caused by HEV and EBV coinfection

Qi LiNa, Wang ShuHua, Guo XiangLing, Gao RunPing

2017, 33(4): 728-729. DOI: 10.3969/j.issn.1001-5256.2017.04.027

Abstract(2132)

PDF (1500KB)(474) Cited By (4)

Abstract:

Long-term relief in patients with hepatocellular carcinoma treated with donafenib tosylate: a report of two cases

Hu Yue, Lou JinFeng, Liu JingRui, Ding YanHua, Ma Yun, Niu JunQi

2017, 33(4): 730-731. DOI: 10.3969/j.issn.1001-5256.2017.04.028

Abstract(3123)

PDF (1446KB)(477) Cited By (7)

Abstract:

A case of primary hepatocellular carcinoma with lung adenocarcinoma and liver metastasis

Pan Meng, Wang Le, Li Xu, Gao PuJun

2017, 33(4): 732-734. DOI: 10.3969/j.issn.1001-5256.2017.04.029

Abstract(2577)

PDF (1866KB)(454) Cited By (3)

Abstract:

Severe liver injury caused by chronic inhalation of toluene and xylene: a case report

Mi HongMei, Liu Ning, Shang Li, Wang Lei

2017, 33(4): 735-737. DOI: 10.3969/j.issn.1001-5256.2017.04.030

Abstract(2091)

PDF (1483KB)(463) Cited By (2)

Abstract:

A case of idiopathic portal hypertension

Zhang Yong, Tang ShanHong, Mou Dong, Zheng ShuMei, Ceng WeiZheng

2017, 33(4): 738-739. DOI: 10.3969/j.issn.1001-5256.2017.04.031

Abstract(1965)

PDF (1564KB)(475) Cited By (4)

Abstract:

Laparoscopic cholecystectomy for cold agglutinin syndrome with gallstones: a case report

Wang Bin, Luo Xiao, Sun BaoZhen, Yang Guang, Meng ZiHui, Ji DeGang

2017, 33(4): 740-741. DOI: 10.3969/j.issn.1001-5256.2017.04.032

Abstract(1353)

PDF (1445KB)(414) Cited By (5)

Abstract:

A case of hemochromatosis with anemia and severe jaundice

Zhu Min, Li DongYing, Du BaiXue, Li JianSheng

2017, 33(4): 742-743. DOI: 10.3969/j.issn.1001-5256.2017.04.033

Abstract(1753)

PDF (1548KB)(439) Cited By (2)

Abstract:

Laparoscopic splenectomy in treatment of splenic angiosarcoma: a case report

Zhang YiWei, Zhang Wei, Liu Feng, Liu YaHui

2017, 33(4): 744-745. DOI: 10.3969/j.issn.1001-5256.2017.04.034

Abstract(452)

PDF (167KB)(104) Cited By (5)

Abstract:

Reviews

Research advances in the application of telbivudine during pregnancy to prevent HBV mother-to-child transmission

Wang Chong, Cao MengZhuo, Wang Chuan, Jiang Jing, Li Jie, Niu JunQi

2017, 33(4): 746-750. DOI: 10.3969/j.issn.1001-5256.2017.04.035

Abstract(2263)

PDF (1485KB)(443) Cited By (14)

Abstract:
Almost 10% of neonates whose mothers have a high HBV DNA load may have HBV infection, even after the preventive treatment with hepatitis B vaccine and immune interruption. In pregnant women with a high HBV DNA load, nucleos ( t) ide analogues ( lamivudine, telbivudine, and tenofovir) have been used ...

Research advances in hepatitis B virus reactivation

Li MengYuan, Ye ChuanTao, Zhang Ying, Jia ZhanSheng

2017, 33(4): 751-756. DOI: 10.3969/j.issn.1001-5256.2017.04.036

Abstract(585)

PDF (249KB)(159) Cited By (8)

Abstract:
In non-active or cured patients with hepatitis B virus ( HBV) infection, when the body's immune homeostasis is broken, HBV reactivation may occur, with the manifestations of liver inflammation and increased HBV DNA level, and lead to varying degrees of abnormal liver function, liver failure, and eve...

Diabetes mellitus and primary liver cancer: risk factor or real cause?

Liang Jing, Han Tao

2017, 33(4): 757-762. DOI: 10.3969/j.issn.1001-5256.2017.04.037

Abstract(582)

PDF (246KB)(364) Cited By (25)

Abstract:
With an increasing prevalence all over the world, diabetes mellitus is considered as a potential cause of liver cancer in patients with non-viral hepatitis. Whether diabetes mellitus is the cause of liver cancer and related pathogenesis remain unknown. The article reviews recent large-sample cohort ...

Research advances in insulin-like growth factor 1 receptor and its pathway in diagnosis and treatment of primary liver cancer

Zhao Zhao, Qi WenQian, Zhao Ping

2017, 33(4): 763-768. DOI: 10.3969/j.issn.1001-5256.2017.04.038

Abstract(539)

PDF (316KB)(158) Cited By (5)

Abstract:
The main biological functions of insulin-like growth factor 1 receptor ( IGF-1R) include formation and maintenance of transformed cell phenotype, involvement in cell proliferation and differentiation, and inhibition of cell apoptosis. In addition, IGF-1R regulates cell cycle and works with epidermal...

Research advances in the pathogenesis of nonalcoholic fatty liver disease

Wang Hu, Teng Tian, Wang Li, Zhou Meng, Yan HongRu, Sun Ying

2017, 33(4): 769-773. DOI: 10.3969/j.issn.1001-5256.2017.04.039

Abstract(2509)

PDF (1480KB)(547) Cited By (24)

Abstract:
Nonalcoholic fatty liver disease ( NAFLD) has been developing rapidly in recent years and has become one of the most common liver diseases. However, its pathogenesis remains unclear, and there are no widely accepted therapeutic regimens. NAFLD has a complex pathogenesis with multiple factors involve...

Gut microbiota and nonalcoholic fatty liver disease

Xiao Li, Yang Ling

2017, 33(4): 774-779. DOI: 10.3969/j.issn.1001-5256.2017.04.040

Abstract(2178)

PDF (1493KB)(448) Cited By (48)

Abstract:
Nonalcoholic fatty liver disease ( NAFLD) is a common liver disease with multiple factors involved, and its incidence is gradually increasing around the world. Recent studies have found that gut microbiota is involved in the development and progression of NAFLD. This article summarizes the associati...

Research advances in association between blood neutrophil/lymphocyte ratio and prognosis of related liver diseases

Li Qiao, Guo HongHua

2017, 33(4): 780-784. DOI: 10.3969/j.issn.1001-5256.2017.04.041

Abstract(1812)

PDF (1509KB)(380) Cited By (17)

Abstract:
Recent studies have found that inflammatory response is positively associated with the progression of liver cirrhosis, acute-on-chronic liver failure, and primary liver cancer and can affect their prognosis, and as a marker for inflammatory response, neutrophil/lymphocyte ratio ( NLR) is easy to cal...

Research advances in minimally invasive treatment of infectious pancreatic necrosis

Wu DongDong, Yang XiaoYan, Gao Feng

2017, 33(4): 785-789. DOI: 10.3969/j.issn.1001-5256.2017.04.042

Abstract(1726)

PDF (1711KB)(364) Cited By (17)

Abstract:
Infectious pancreatic necrosis ( IPN) is a challenging complication of acute pancreatitis and can lead to poor prognosis. Over the years, open necrosectomy has become the main treatment modality for IPN, but it will cause high incidence rate of complications and mortality rate. In recent years, with...

Research advances in insulin-like growth factor-1 receptor in pancreatic cancer

Wang YueChao, Qi WenQian, Zhao Ping

2017, 33(4): 790-794. DOI: 10.3969/j.issn.1001-5256.2017.04.043

Abstract(1801)

PDF (1545KB)(418) Cited By (12)

Abstract:
Insulin-like growth factor-1 receptor ( IGF-1R) widely exists in the surface of various types of cells and is closely associated with the formation and development of tumor cells. It also provides a new direction for the targeted therapy for tumors. This article reviews the expression, development, ...

Conference overviews

Minutes of the meeting on new diagnostic techniques for portal hypertension at the 26th Conference of the Asian Pacific Association for the Study of the Liver

Qi XiaoLong, Xiang Yi, Hou JinLin

2017, 33(4): 795-796. DOI: 10.3969/j.issn.1001-5256.2017.04.044

Abstract(1414)

PDF (1440KB)(384) Cited By (3)

Abstract: