中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 5
May  2017

Risk factors for recurrence after surgery for biliary pancreatitis

DOI: 10.3969/j.issn.1001-5256.2017.05.025
  • Published Date: 2017-05-20
  • Objective To investigate the risk factors for recurrence after surgery for biliary pancreatitis.Methods A total of 284 patients with biliary pancreatitis who were treated in The Fourth Hospital of PLA from January 2008 to December 2014 were followed up, and the risk factors for postoperative recurrence were analyzed.The chi-square test was used for categorical data, and the unconditional logistic regression model was used for multivariate analysis.Results The follow-up period ranged from 6 to 27 months (mean 36.4 ± 8.4 months) .Of all patients, 27 experienced recurrence, and the recurrence rate was 9.51%.The univariate analysis showed that postoperative recurrence was associated with a family history of gallstone disease, high-fat diet, sand-like stones, intrahepatic bile duct stones, biliopancreatic duct opening stenosis, and diverticulum around the ampullar region (χ2=8.721, 5.979, 8.641, 15.996, 33.833, and 27.203, all P<0.05) .The multivariate logistic analysis showed that high-fat diet (OR=2.296, P=0.012) , biliopancreatic duct opening stenosis (OR=2.280, P=0.007) , and diverticulum around the ampullar region (OR=2.522, P=0.009) were independent risk factors for recurrence after surgery for biliary pancreatitis.Conclusion Biliary pancreatitis patients with high-fat diet, biliopancreatic duct opening stenosis, or diverticulum around the ampullar region tend to experience recurrence after surgery.Intervention and close follow-up should be performed for these patients to prevent recurrence.

     

  • [1]ZHANG TT, HAN Z.Research advances in disease evaluation and early treatment methods for acute biliary pancreatitis[J].Tnt J Dig Dis, 2016, 36 (3) :160-163. (in Chinese) 张婷婷, 韩真.急性胆源性胰腺炎病情评估及早期治疗方法的研究进展[J].国际消化病杂志, 2016, 36 (3) :160-163.
    [2]ZHU YJ, XIE K, ZHAO YJ, et al.Surgical treatment of biliary duct diseases in acute biliary pancreatitis[J].Chin J Gen Surg, 2016, 25 (9) :1324-1330. (in Chinese) 朱永吉, 谢坤, 赵义军, 等.急性胆源性胰腺炎胆道疾病的外科处理[J].中国普通外科杂志, 2016, 25 (9) :1324-1330.
    [3]ZHOU YF, CHEG GZ, ZHANG KH.Application of different minimally invasive techniques in patients with biliary pancreatitis[J].Clin J Curr Adv Gen Surg, 2016, 19 (5) :408-410, 414. (in Chinese) 周云飞, 成功志, 张开红.不同微创技术在胆源性胰腺炎患者中的应用[J].中国现代普通外科进展, 2016, 19 (5) :408-410, 414.
    [4] Pancreas Study Group, Chinese Society of Gastroenterology, Chinese Medical Association, Editorial Board of Chinese Journal of Pancreatology, Editorial Board of Chinese Journal of Digestion.China Guidelines for the management of acute pancreatitis (2013, Shanghai) [J].Chin J Dig, 2013, 33 (4) :217-222. (in Chinese) 中华医学会消化病学分会胰腺疾病学组, 中华胰腺病杂志编辑委员会, 中华消化杂志编辑委员会.中国急性胰腺炎诊治指南 (2013年, 上海) [J].中华消化杂志, 2013, 33 (4) :217-222.
    [5]QIAO H, HE SJ.Clinical analysis of 87 cases of recurrent biliogenic pancreatitis[J].Chongqing Med J, 2003, 32 (6) :740-741. (in Chinese) 乔华, 何世举.胆源性复发性胰腺炎87例的临床分析[J].重庆医学, 2003, 32 (6) :740-741.
    [6]ZHU WG, ZHENG XP.Analysis of risk factors for postoperative recurrence of common bile duct stones[J].J Qiqihar Univ Med, 2016, 37 (16) :2050-2052. (in Chinese) 朱卫国, 郑小平.胆总管结石术后复发的相关危险因素分析[J].齐齐哈尔医学院学报, 2016, 37 (16) :2050-2052.
    [7]LU ZH, NIU J, XU PP, et al.Analysis of related risk factors for recurrence of choledocholithiasis after the operation[J].Chin J Curr Adv Gen Surg, 2016, 19 (5) :372-375. (in Chinese) 鲁志华, 牛军, 许平平, 等.胆总管取石并胆囊切除术后胆总管结石复发的相关危险因素分析[J].中国现代普通外科进展, 2016, 19 (5) :372-375.
    [8]CRIDDLE DN.The role of fat and alcohol in acute pancreatitis:a dangerous liaison[J].Pancreatology, 2015, 15 (4 Suppl) :s6-s12.
    [9]PAN G, CHEN YF, CAI J, et al.The clinical value of clinical characteristics and prognosis of elderly patients with hyperlipidemic acute pancreatitis[J].Clin J Med Offic, 2016, 44 (6) :579-582. (in Chinese) 潘刚, 陈亚峰, 蔡杰, 等.老年高脂血症性急性胰腺炎临床特点及预后评估因素分析[J].临床军医杂志, 2016, 44 (6) :579-582.
    [10]LYU K, CHEN X.Clinical features of recurrent biliary pancreatitis and its predisposing factors[J].J Clin Hepatol, 2016, 32 (1) :127-130. (in Chinese) 吕坤, 陈翔.复发性胆源性胰腺炎的临床特点及诱发因素分析[J].临床肝胆病杂志, 2016, 32 (1) :127-130.
    [11]YANG WL, ZHANG XC.Selection and evaluation of surgical procedures for the treatment of duodenal papillary stenosis[J].J Postgraduates Med, 2004, 27 (20) :57-59. (in Chinese) 杨维良, 张新晨.十二指肠乳头良性狭窄治疗的术式选择与评价[J].医师进修杂志, 2004, 27 (20) :57-59.
    [12]ZOEPF T, ZOEPF DS, ARNOLD JC, et al.The relationship between juxtapapillary duodenal diverticula and disorders of the biliopancreatic system:analysis of 350 patients[J].Gastrointest Endosc, 2001, 54 (1) :56-61.
    [13]VAZQUEZ-LGLESIAS JL, GONZALEZ-CONDE B, LOPEZ-ROSES L, et al.Endoscopic sphincterotomy for prevention of the recurrence of acute biliary pancreatitis in patients with gallbladder in situ:long-term follow-up of 88 patients[J].Surg Endosc, 2004, 18 (10) :1442-1446.
    [14]WANG ZK, YANG YS, SUN G.Prevention and treatment of long-term complications after endoscopic sphincterotomy for common bile duct stones should be taken seriously[J].Natl Med J China, 2014, 94 (40) :3124-3126. (in Chinese) 王子恺, 杨云生, 孙刚.应重视胆总管结石EST术后远期并发症的防治[J].中华医学杂志, 2014, 94 (40) :3124-3126.
  • Relative Articles

    [1]Shaoxuan LUO, Ya LI, Feng XU. A case of hepatolenticular degeneration with hepatocellular carcinoma[J]. Journal of Clinical Hepatology, 2022, 38(5): 1119-1121. doi: 10.3969/j.issn.1001-5256.2022.05.028
    [2]Weiyuan FANG, Yi LU. Diagnosis and treatment of acute liver failure in children with Wilson's disease[J]. Journal of Clinical Hepatology, 2022, 38(2): 268-272. doi: 10.3969/j.issn.1001-5256.2022.02.004
    [3]Weiyuan FANG, Jianshe WANG. An excerpt of investigation and management of Wilson's disease: A practical guide from the British Association for the Study of the Liver (2022)[J]. Journal of Clinical Hepatology, 2022, 38(6): 1256-1257. doi: 10.3969/j.issn.1001-5256.2022.06.009
    [4]Wei ZHANG, Jian HUANG, Xiaojuan OU, Jidong JIA. Key points of AASLD practice guidance for the diagnosis and treatment of Wilson's disease (2022)[J]. Journal of Clinical Hepatology, 2022, 38(12): 2709-2711. doi: 10.3969/j.issn.1001-5256.2022.12.006
    [5]Zhou SiMin, Guo LiPing, Cai WangFeng, Zhou Lu, Wang BangMao. Latest advances in the treatment of hepatolenticular degeneration[J]. Journal of Clinical Hepatology, 2020, 36(1): 218-221. doi: 10.3969/j.issn.1001-5256.2020.01.052
    [6]Lu: Jia, Zhao Gang, Sun XueHua, Gao YueQiu. A case of hepatolenticular degeneration with neurological disorders as the prominent symptom[J]. Journal of Clinical Hepatology, 2019, 35(7): 1591-1593. doi: 10.3969/j.issn.1001-5256.2019.07.034
    [8]Huang DeLiang, Zhu ZhiBin, Yu Hong, Zhao Qi, Jiang JinYan, Chen YuanYuan, Dai Wei. Hepatolenticular degeneration with polycystic ovary syndrome: a case report[J]. Journal of Clinical Hepatology, 2018, 34(10): 2195-2196. doi: 10.3969/j.issn.1001-5256.2018.10.027
    [9]Li Xiang, Cai Jie, Xu YuWen, Yang Fen, Sun ALei, Weng YaLi. A case of hepatolenticular degeneration with hepatocellular carcinoma[J]. Journal of Clinical Hepatology, 2018, 34(9): 1967-1971. doi: 10.3969/j.issn.1001-5256.2018.09.027
    [10]Cheng Ran, Li YiJing, Fang Shu, Xu XiaoYuan, Wan Hua. A case of Wilson′s disease in adults with liver disease as the initial manifestation[J]. Journal of Clinical Hepatology, 2018, 34(3): 607-609. doi: 10.3969/j.issn.1001-5256.2018.03.035
    [11]Li ChunXia, Gong JingYu, Zhang MeiHong, Wang JianShe. Effect of pharmacotherapy on decompensated liver function in children with hepatolenticular degeneration[J]. Journal of Clinical Hepatology, 2017, 33(8): 1543-1547. doi: 10.3969/j.issn.1001-5256.2017.08.027
    [12]Fang Feng. Long-term treatment and follow-up management of children with hepatolenticular degeneration[J]. Journal of Clinical Hepatology, 2017, 33(10): 1936-1938. doi: 10.3969/j.issn.1001-5256.2017.10.017
    [13]Mao JiaXi, Zou You, Guo WenYuan. Clinical effect of liver transplantation in the treatment of hepatolenticular degeneration[J]. Journal of Clinical Hepatology, 2017, 33(10): 1977-1980. doi: 10.3969/j.issn.1001-5256.2017.10.026
    [14]Cui YuanYuan, Yang YiLiang, Wang ShaSha, Hua Rui. A case of hepatolenticular degeneration with mental disorder as initial symptomc[J]. Journal of Clinical Hepatology, 2016, 32(11): 2173-2174. doi: 10.3969/j.issn.1001-5256.2016.11.037
    [15]Yang Xu. Update on diagnosis and treatment of Wilson disease in China[J]. Journal of Clinical Hepatology, 2013, 29(12): 905-908. doi: 10.3969/j.issn.1001-5256.2013.12.008
    [16]Fan ZhenPing, Zhang HaiYan, Cai ShaoPing, Ji YingJie, Shi XueMin, Zhang WenJin. Diagnosis and treatment of hepatolenticular degeneration in adult patients with primary liver diseases[J]. Journal of Clinical Hepatology, 2013, 29(12): 940-942. doi: 10.3969/j.issn.1001-5256.2013.12.017
    [17]Lu Yi, Wang JianShe. Diagnosis of Wilson's disease in children[J]. Journal of Clinical Hepatology, 2012, 28(12): 907-910.
    [18]Wang ChaoXia, Zhang ChunYan. Clinical features and progress in diagnosis and treatment of hepatolenticular degeneration in children[J]. Journal of Clinical Hepatology, 2011, 27(7): 703-705.
  • Cited by

    Periodical cited type(4)

    1. 赵贺,王冲,张文静,邵思论. 术前LSR、NLR及PLR检测评估结直肠癌预后的应用价值. 分子诊断与治疗杂志. 2022(02): 228-231+236 .
    2. 闫伟,戴雪娥,郉晓宇,陈韭铭. 肝癌患者TACE治疗前后血清免疫炎症相关因子的变化及意义. 中国肿瘤临床与康复. 2022(03): 269-273 .
    3. 邰新苗,张月怡,李继伟. 外周血中性粒细胞与淋巴细胞比值联合甲胎蛋白对HBV相关肝细胞癌的诊断价值. 现代消化及介入诊疗. 2021(03): 391-394 .
    4. 张小芳,刘志良,蔡勇,黄传生,罗庆丰. HIF-1α、MITF、CRP、NLR在乙型肝炎病毒感染相关性肝癌中的表达及其意义. 实用癌症杂志. 2021(07): 1084-1086 .

    Other cited types(6)

  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (1844) PDF downloads(389) Cited by(10)
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return