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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 37 Issue 7
Jul.  2021
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Article Navigation >  Journal of Clinical Hepatology  > 2021  >  37(7): 1652-1656

Effect of Braun anastomosis on delayed gastric emptying after pancreaticoduodenectomy

DOI: 10.3969/j.issn.1001-5256.2021.07.034
  • 1.

    The First Clinical Medical College, Lanzhou University, Lanzhou 730000, China

  • 2.

    Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, China

Research funding:

The Key Research and Development Fund Project of Gansu Provincial Department of Science and Technology (17YF1FA128);

Research Program of Gansu Province Health Industry (GSWSKY2018-51)

  • Received Date: 2020-12-15
  • Accepted Date: 2021-01-19
  • Published Date: 2021-07-20
    Abstract
  •   Objective  To investigate the effect of Braun anastomosis (BE) on delayed gastric emptying (DGE) after pancreaticoduodenectomy (PD).  Methods  A retrospective analysis was performed for the clinical data of 132 patients who underwent PD in The First Hospital of Lanzhou University from December 2016 to December 2019, and according to whether BE was performed during surgery, the patients were divided into BE group with 54 patients and non-BE group with 78 patients. The two groups were compared in terms of postoperative complications (DGE, pancreatic fistula, and biliary fistula), intraoperative condition, general examination indicators, postoperative treatment and recovery, and hospitalization to evaluate the effect of BE in preventing DGE after PD. The t-test was used for comparison of normally distributed continuous data between two groups, and the Mann-Whitney U test was used for comparison of non-normally distributed continuous data between two groups; the chi-square test and the Fisher's exact test were used for comparison of categorical data between two groups.  Results  Compared with the non-BE group, the BE group had a significantly lower incidence rate of grade C DGE after surgery (5.56% vs 19.23%, χ2=5.067, P < 0.05), a significantly shorter time to the first chemotherapy [45.00 (38.00-49.75) days vs 53.00 (44.00-65.00) days, H=-2.495, P=0.013], a significantly shorter length of postoperative hospital stay [15.00 (12.75-19.25) days vs 18.00 (15.00-25.50) days, H=-3.358, P < 0.05], and a significantly lower number of times of the use of antiemetic drugs [1.00(0-0.25) times vs 1.00(1.00-4.00) times, H=-2.347, P=0.019]. There were no significant differences between the two groups in the time of operation, intraoperative blood loss, hospital cost, survival time, duration of gastric tube placement, time to resume eating, and overall incidence rates of DGE, pancreatic fistula, biliary fistula, gastrointestinal fistula, abdominal bleeding, incision infection, wound dehiscence, and intestinal obstruction (all P > 0.05).  Conclusion  BE can effectively reduce the incidence rate of grade C DGE after PD.

     

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