As the only effective way for the treatment of end- stage liver disease, liver transplantation has been developed rapidly in China over recent years. The latest developments of liver transplantation in China are reviewed, including establishment of selection criteria for the liver cancer recipients ...
Abstract: Hepatocellular carcinoma ( HCC) is still a prevalent gastrointestinal cancer. Liver transplantation ( LT) is one of the main means in the comprehensive treatment of HCC because it radically removes the tumor. However, tumor recurrence and metastasis after LT remain the main obstacles to long- term s...
Abstract: Liver transplantation is an important treatment for end- stage liver disease, but donor shortage is becoming increasingly apparent, so donation after cardiac death ( DCD) , which is suitable for the national conditions of China and consistent with international standards, is an important measure for...
Abstract: The best choice of treatment for patients with HCV- related cirrhosis may be liver transplantation once liver decompensation occurs. Immunoregulatory drugs, especially immunosuppressants, may be a main causative factor for accelerated HCV recurrence after liver transplantation. How to control HCV in...
Objective To compared the prognosis between infants with biliary atresia ( BA) who underwent living donor liver transplantation ( LDLT) during 2006- 2009 and 2010- 2012 in the Department of Liver Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine and to evaluate the prognos is ...
Objective To analyze the rationality of delivery method for hepatitis B immune globulin ( HBIG) in patients with chronic hepatitis B virus ( HBV) infection after liver transplantation and to investigate the guiding principle for medication. Methods Forty- four cases of hepatitis B- related liver tra...
Objective To perform antiviral therapy in patients with recurrent hepatitis C after liver transplantation and to study the efficacy of antiviral therapy and its effect on the progression of liver fibrosis. Methods Twenty- three patients with recurrent hepatitis C after liver transplantation who were...
Abstract: Objective To investigate the epidemiological features and serological changes in sporadic acute hepatitis B ( AHB) among adults. Methods A total of 202 adult patients with AHB were selected as subjects. The epidemiological data of patients were collected, and follow- up was regularly performed for 4...
Abstract: Objective To investigate the clinical significance of noninvasive predictive indices of esophageal varices ( EV) in patients with posthepatitic cirrhosis. Methods Sixty- four patients with posthepatitic cirrhosis, who were hospitalized in the Affiliated Hospital of Yan'an University from February 20...
Objective To analyze the prognostic factors in patients with hepatitis B- related primary liver cancer treated with transcatheter arterial chemoembolization ( TACE) and to provide a basis for properly selecting indications and treatment regimen in clinical practice. Methods A total of 140 patients w...
Objective To evaluate the clinical effect of transcatheter arterial chemoembolization ( TACE) alone or combined with tegafur, gimeracil, and oteracil potassium ( S- 1) in the treatment of advanced hepatocellular carcinoma ( HCC) . Methods Sixty patients with unresectable advanced HCC, who were admit...
Abstract: Objective To analyze the clinical features of cholangiolithiasis with cavernous transformation of the portal vein ( CTPV) and to investigate the surgical treatment of this disease. Methods A retrospective analysis was performed on the clinical data of 18 patients with cholangiolithiasis with CTPV wh...
Abstract: Objective To investigate the safety, feasibility, and operation skills of spleen- preserving laparoscopic distal pancreatectomy ( SPLDP) in the treatment of tumors in the body and tail of the pancreas. Methods A retrospective analysis was performed on the medical records of 12 patients who underwent...
Abstract: Objective To investigate the relationship between gallstone morphology and acute pancreatitis. Methods A total of 110 patients with biliary pancreatitis, who were admitted to our hospital from February 2011 to February 2013, were selected as pancreatitis group, while 110 patients with gallstones wer...
Objective To analyze the clinical data, laboratory parameters, infection rate, and serum procalcitonin ( PCT) and ET- 1 levels of patients with cirrhotic ascites and type 1 hepatorenal syndrome ( HRS) and to investigate the roles of endotoxin and ET- 1 in the development of HRS. Methods Between Janu...
Objective To investigate and assess prognostic factors for survival in patients with primary biliary cirrhosis ( PBC) by receiver operating characteristics ( ROC) curves and Kaplan- Meier methods. Methods A total of 155 patients were identified and followed. Terminal events were death and / or liver...
Abstract: Liver transplantation is an effective treatment for acute liver failure, decompensated cirrhosis, hepatocellular carcinoma, and other end- stage liver diseases. In recent years, with the improvements in patients' understanding of medical technology and their requirement for postoperative quality of ...
Abstract: Hepatitis B virus ( HBV) X protein ( HBx) is a multifunctional protein encoded by HBV X gene. It plays a regulatory role in gene transcription, cell signal transduction, cell proliferation and transformation, cell cycle, and cell apoptosis. Currently, HBx is considered to play an important role in t...
Abstract: Substantial progress has been made in the stem cell therapy for liver fibrosis. However, the therapeutic effect is limited by decreased self- renewal of stem cells during migration. Therefore, to improve the self- renewal of stem cells after transplantation is urgent and essential for the successful...
Abstract: Budd- Chiari syndrome and portal vein thrombosis are two rare vascular disorders of the liver and may be complicated by severe diseases like liver failure and portal hypertension. Studies have shown that factor V Leiden ( FVL) mutation is an important risk factor for both Budd- Chiari syndrome and p...