中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

2016 No. 7

Display Method:
Therapeutic guidelines
Clinical guidelines for pediatric liver transplantation in China( 2015)
Organ Transplantation Branch, Chinese Medical Doctor Association, Chinese Society of Organ Transplantation, Chinese Medical Association
2016, 32(7): 1235-1244. DOI: 10.3969/j.issn.1001-5256.2016.07.001
Abstract(457) PDF (363KB)(594) Cited By (42)
Abstract:
An excerpt of APASL consensus statements and recommendation on treatment of hepatitis C (2016)
Zhang Ying, Leng XueJun, Shen JiaoChun, Yan XueBing
2016, 32(7): 1245-1247. DOI: 10.3969/j.issn.1001-5256.2016.07.002
Abstract(286) PDF (158KB)(137) Cited By (2)
Abstract:
Recommendations for WHO guidelines for the screening, care and treatment of persons with chronic hepatitis C infection: a 2016 update
Zhang Ning, Luo ShengQiang
2016, 32(7): 1248-1249. DOI: 10.3969/j.issn.1001-5256.2016.07.003
Abstract(319) PDF (176KB)(252) Cited By (6)
Abstract:
Committee on gynecologic practice of the American College of Obstetricians and Gynecologists:hepatitis B, hepatitis C, and human immunodeficiency virus infections in obstetrician-gynecologists
Li Peng, Ding HuiGuo
2016, 32(7): 1250-1252. DOI: 10.3969/j.issn.1001-5256.2016.07.004
Abstract:
ASGE guideline: the role of endoscopy in the diagnosis and treatment of inflammatory pancreatic fluid collections: a 2016 update
Liang Bing, He Song
2016, 32(7): 1253-1255. DOI: 10.3969/j.issn.1001-5256.2016.07.005
Abstract(329) PDF (153KB)(149) Cited By (3)
Abstract:
Recommendation about hepatitis E in children: a position paper by the ESPGHAN Hepatology Committee 2016
Jiang Yong, Han Tao
2016, 32(7): 1256-1257. DOI: 10.3969/j.issn.1001-5256.2016.07.006
Abstract:
An excerpt of Australian recommendations for the management of hepatitis C virus infection: a consensus statement
Leng XueJun, Zhang Ying, Shen JiaoChun, Yan XueBing
2016, 32(7): 1258-1261. DOI: 10.3969/j.issn.1001-5256.2016.07.007
Abstract:
Discussions by experts
Strategy for virologic response-guided therapy in integrated diagnosis and treatment of hepatitis C in the era of precision medicine in China
Zhou HuiJuan, Xie Qing
2016, 32(7): 1262-1265. DOI: 10.3969/j.issn.1001-5256.2016.07.008
Abstract(306) PDF (188KB)(128) Cited By (5)
Abstract:
At present,long- acting interferon combined with ribavirin is still a major therapeutic method for hepatitis C in China,and precision medicine can help cure more patients with hepatitis C. This article briefly introduces the diagnosis and treatment of hepatitis in China and the importance of the str...
Prognostic evaluation of primary biliary cirrhosis and its value in guiding therapeutic regimens
Huang ChunYang, Liu YanMin
2016, 32(7): 1266-1272. DOI: 10.3969/j.issn.1001-5256.2016.07.009
Abstract(2312) PDF (1550KB)(509) Cited By (10)
Abstract:
Prognostic evaluation of patients with primary biliary cirrhosis( PBC) and how to improve the prognosis have attracted much attention. Further therapeutic regimens for PBC patients with poor prognosis has become the direction of clinical and scientific studies. This article summarizes the associatio...
Endoscopic ultrasound and multi-slice spiral CT portal venography in diagnosis and treatment of portal hypertension
Lu Wei, Zhou Li, Li Shuang
2016, 32(7): 1273-1276. DOI: 10.3969/j.issn.1001-5256.2016.07.010
Abstract(2138) PDF (1512KB)(440) Cited By (6)
Abstract:
At present,endoscopic ultrasound and multi- slice spiral CT portal venography are effective methods to assess the portal vein and collateral circulation. Endoscopic ultrasound can clearly show the blood vessels inside and outside the esophageal wall and in surrounding tissues,as well as the image of...
Clinical application of combined vascular resection and reconstruction in surgical treatment of hilar cholangiocarcinoma
Chen ZhiYu, Bie Ping
2016, 32(7): 1277-1279. DOI: 10.3969/j.issn.1001-5256.2016.07.011
Abstract(1980) PDF (1500KB)(402) Cited By (17)
Abstract:
The surgical treatment of hilar cholangiocarcinoma is one of the most challenging routine surgeries in the field of hepatobiliary surgery,and vascular invasion is an important reason for the low rate of radical resection in hilar cholangiocarcinoma. Currently,it is universally acknowledged that rese...
Application of endoscopic ultrasonography in diagnosis of pancreatic cancer and related research advances
He Qiang, Xu YouQing
2016, 32(7): 1280-1282. DOI: 10.3969/j.issn.1001-5256.2016.07.012
Abstract(566) PDF (185KB)(225) Cited By (8)
Abstract:
At present,traditional imaging techniques for the diagnosis of early- stage pancreatic cancer lack enough sensitivity,and therefore,early diagnosis of pancreatic cancer is still the biggest challenge in precision medicine around the world. Based on a large amount of clinical practice and the develop...
Original articles_Viral hepatitis
Criteria for withdrawal of nucleos( t) ide analogues and their clinical significance in treatment of chronic hepatitis B
Chen HeMin, Shao GuoHui
2016, 32(7): 1283-1286. DOI: 10.3969/j.issn.1001-5256.2016.07.013
Abstract(2892) PDF (1531KB)(511) Cited By (10)
Abstract:
Objective To investigate the association of virologic relapse after withdrawal of nucleos( t) ide analogues( NAs) with HBs Ag quantitation and HBV DNA load at withdrawal in patients with chronic hepatitis B( CHB). Methods A total of 205 CHB patients who were treated with NAs in the outpatient servic...
Establishment of a predictive model for early virologic response in previously untreated chronic hepatitis B patients treated with telbivudine
Huang ShuiWen, Liu BaoRong, Chen MingSheng, Lin Chun, Zhou Rui, Yang HuiAn, Jiang XiaoYan, Pan Chen, Li DongLiang
2016, 32(7): 1287-1291. DOI: 10.3969/j.issn.1001-5256.2016.07.014
Abstract(2304) PDF (1571KB)(454) Cited By (3)
Abstract:
Objective To investigate the establishment of a predictive model for early virologic response in previously untreated chronic hepatitis B( CHB) patients treated with telbivudine,since early virologic response can predict the long- term efficacy of nucleotide analogues.Methods A total of 135 CHB pati...
Association between serum level of interleukin-17 and HBsAg clearance in patients with HBsAg-negative chronic hepatitis B
Cao ZhenHuan, Liu YaLi, Ma LiNa, Lu JunFeng, Jin Yi, He ZhiMin, Zheng YanHong, Chen XinYue
2016, 32(7): 1292-1295. DOI: 10.3969/j.issn.1001-5256.2016.07.015
Abstract(2232) PDF (1584KB)(462) Cited By (2)
Abstract:
Objective To investigate the association between HBsAg clearance and serum level of interleukin- 17( IL- 17) in HBeAg-negative chronic hepatitis B( CHB) patients treated by pegylated interferon( PEG- IFN). Methods A total of 13 HBeAg- negative CHB patients who visited Beijing You An Hospital from Ja...
Effect and safety of bilirubin serum adsorption in treatment of patients with chronic severe hepatitis B
Wang QingHai, Luo KaiZhong, Tian Yi
2016, 32(7): 1296-1299. DOI: 10.3969/j.issn.1001-5256.2016.07.016
Abstract(2356) PDF (1747KB)(453) Cited By (12)
Abstract:
Objective To investigate the effect and safety of bilirubin serum adsorption( BSA) in the treatment of patients with chronic severe hepatitis B. Methods A prospective study was performed for 40 patients with chronic severe hepatitis B[prothrombin activity( PTA)> 25%] who were hospitalized in The ...
Efficacy of low-dose glucocorticoids in treatment of HBV-related acute-on-chronic liver failure
Qiu Bo, Zhu Ling, Wang TangMing, Yan ShiChun, Zhang JianMing, Xie ZhiAn, Liu XingYu
2016, 32(7): 1300-1304. DOI: 10.3969/j.issn.1001-5256.2016.07.017
Abstract(2298) PDF (1536KB)(492) Cited By (18)
Abstract:
Objective To investigate the efficacy and safety of low- dose glucocorticoids in the treatment of HBV- related acute- on-chronic liver failure( HBV- ACLF). Methods A total of 118 patients with HBV- ACLF who were treated in Center for Liver Disease Treatment in the Fourth People's Hospital of Panzhih...
Familial aggregation and clinical prognosis of hepatitis B virus infection in Guangzhou,China
Ye JunZhao, Wu YanQin, Li Rui, Li ShaoFeng, Zhong BiHui
2016, 32(7): 1305-1309. DOI: 10.3969/j.issn.1001-5256.2016.07.018
Abstract(2042) PDF (1534KB)(422) Cited By (8)
Abstract:
Objective To investigate the characteristics of familial aggregation and prognosis of chronic hepatitis B( CHB) in Guangzhou,China,where there is a high prevalence of hepatitis B virus( HBV) infection. Methods The CHB patients who were treated in Outpatient Department of Hepatitis in the First Affil...
Independent predictive factors for significant liver histological changes in patients with HBe Ag-positive high-viral-load chronic HBV infection and a normal alanine aminotransferase level
Li Qiang, Huang YuXian, Chen Liang
2016, 32(7): 1310-1314. DOI: 10.3969/j.issn.1001-5256.2016.07.019
Abstract(1834) PDF (1573KB)(417) Cited By (15)
Abstract:
Objective To investigate the independent predictive factors for significant liver histological changes( SLHCs) in patients with HBe Ag- positive high- viral- load chronic hepatitis B virus( HBV) infection and a normal alanine aminotransferase( ALT) level. Methods A retrospective analysis was perform...
Influence of Notch signaling pathway on interleukin-22 secreted by CD4~+T cells in patients with hepatitis B
Wang Wei, Zhao RongRong, Yang XiaoFei, Huang ZhangXing, Lian JianQi, Wang JiuPing, Zhang Ye
2016, 32(7): 1315-1318. DOI: 10.3969/j.issn.1001-5256.2016.07.020
Abstract(1681) PDF (1642KB)(416) Cited By (5)
Abstract:
Objective To investigate the influence of Notch signaling pathway inhibition on interleukin- 22( IL- 22) secreted by CD4~+T cells in patients with hepatitis B,and to elaborate on the role of the Notch- IL- 22 signaling pathway in the pathogenesis of hepatitis B.Methods A total of 45 previously untre...
Correlation between routine blood test results and antiviral effect in patients with refractory chronic hepatitis C treated with pegylated interferon-α
Chen XiaoYun, Zheng YanHong, Jin Yi, Yu HaiBin, Ma LiNa, Chen XinYue
2016, 32(7): 1319-1322. DOI: 10.3969/j.issn.1001-5256.2016.07.021
Abstract(1713) PDF (1599KB)(404) Cited By (3)
Abstract:
Objective To investigate the correlation between the changes in routine blood test results and antiviral effect in patients with refractory chronic hepatitis C receiving standard treatment. Methods A total of 63 previously untreated patients with refractory chronic hepatitis C who visited Beijing Yo...
Original articles_Liver fibrosis and liver cirrhosis
Risk genes for the development of chronic hepatitis B cirrhosis assessed by prediction analysis of microarrays
Xiao ChunYang, Li QinKai, Yu JingXia, Liu Ting, Lu LunGen, Xu MingYi
2016, 32(7): 1323-1329. DOI: 10.3969/j.issn.1001-5256.2016.07.022
Abstract(1995) PDF (2138KB)(417) Cited By (1)
Abstract:
Objective To investigate the risk genes for predicting the development of chronic hepatitis B( CHB) cirrhosis using gene chip technology. Methods A total of 40 CHB patients who visited Shanghai First People's Hospital from April 2008 to December 2010 were enrolled as a clinical cohort and were divid...
Effect of decoy receptor 3 gene on hepatocyte apoptosis
Pan LiuLan, Jia ShengNan, Ma JingTing, Tai JingHua, Jin ZhenJing
2016, 32(7): 1330-1333. DOI: 10.3969/j.issn.1001-5256.2016.07.023
Abstract(2105) PDF (212KB)(451) Cited By (3)
Abstract:
Objective To investigate the effect of decoy receptor 3( DcR3) gene on hepatocyte apoptosis,as well as the possible mechanism of action of DcR3 in this process. Methods The human liver cell lines were cultured in vitro,and p EF1α- DcR3 transfection group,p EF1α- IRES transfection group,and negative ...
Original articles_Liver neoplasms
Risk factors for postoperative pulmonary infection in patients with primary liver cancer
Ai YeQing, Zhang ChengHua, Liu HuiFang
2016, 32(7): 1334-1337. DOI: 10.3969/j.issn.1001-5256.2016.07.024
Abstract(2228) PDF (1519KB)(414) Cited By (17)
Abstract:
Objective To investigate the risk factors for postoperative pulmonary infection in patients with primary liver cancer through a retrospective analysis,and to provide a reference for appropriate preventive measures in clinical treatment. Methods A total of 286 patients with liver cancer who visited D...
Value of contrast-enhanced ultrasound in differential diagnosis of single metastatic liver cancer and solitary necrotic nodule of the liver
Li Jing, Tang ShaoShan, Yu HongWei
2016, 32(7): 1338-1341. DOI: 10.3969/j.issn.1001-5256.2016.07.025
Abstract(2157) PDF (1775KB)(397) Cited By (9)
Abstract:
Objective To investigate the value of contrast- enhanced ultrasound( CEUS) in the differential diagnosis of single metastatic hepatic carcinoma( MHC) and solitary necrotic nodule of the liver( SNNL). Methods A retrospective analysis was performed for 12 patients with single MHC and 16 patients with ...
Syndrome differentiation-based treatment of primary liver cancer developed by Professor Qian Ying: an analysis of experience
Li JingYing, Li XiuHui, Zhang Yin, Gou ChunYan, Li Li
2016, 32(7): 1342-1344. DOI: 10.3969/j.issn.1001-5256.2016.07.026
Abstract(2020) PDF (1558KB)(462) Cited By (16)
Abstract:
Objective To investigate the traditional Chinese herbs and core prescriptions commonly used by Professor Qian Ying in the syndrome differentiation- based treatment of primary liver cancer,and to guide clinical medication. Methods A retrospective analysis was performed for the clinical data of the pa...
Original articles_Biliary diseases
The diagnostic value of low-frequency ultrasound combined with high-frequency ultrasound in hyperplastic of the gallbladder
Cheng Lin, Mei Yong
2016, 32(7): 1345-1347. DOI: 10.3969/j.issn.1001-5256.2016.07.027
Abstract(1568) PDF (1540KB)(388) Cited By (11)
Abstract:
Objective To explore the clinical value of low- and high- frequency ultrasound in the diagnosis of benign lesions of the gallbladder.Methods A retrospective analysis was performed in 110 outpatients with pathologically confirmed benign lesions of the gallbladder in our hospital from January 2015 to ...
Experience in clinical diagnosis and treatment of patients aged >65 years with acute calculous cholecystitis
Guo Xin, Lu: XiaoHui, Shi DongLi, Li NingYu, Chen LuBin
2016, 32(7): 1348-1350. DOI: 10.3969/j.issn.1001-5256.2016.07.028
Abstract(2302) PDF (1502KB)(413) Cited By (16)
Abstract:
Objective To investigate the features and methods of clinical diagnosis and treatment of elderly patients with acute calculous cholecystitis. Methods A retrospective analysis was performed for the clinical data of elderly patients who were diagnosed with acute calculous cholecystitis in 451 Hospital...
Recurrence after gallbladder-preserving cholecystolithotomy for sand-like and non-sand-like gallstones: a comparative analysis
Chen Zhi, Zhang HongYi, Xu XinBao, Liu ChengLi, Li XinHui
2016, 32(7): 1351-1353. DOI: 10.3969/j.issn.1001-5256.2016.07.029
Abstract(3155) PDF (1503KB)(474) Cited By (9)
Abstract:
Objective To investigate the recurrence at 1- 3 years after laparoscopic cholecystolithotomy in patients with sand- like and non-sand- like gallstones. Methods A retrospective analysis was performed for the clinical data of 155 patients with gallstones who underwent gallbladder- preserving cholecyst...
Diagnosis,treatment,and outcome of Mirizzi syndrome in the perioperative period of laparoscopic cholecystectomy
Chen LuBin, Lu: XiaoHui, Guo Xin
2016, 32(7): 1354-1356. DOI: 10.3969/j.issn.1001-5256.2016.07.030
Abstract(2178) PDF (1507KB)(418) Cited By (21)
Abstract:
Objective To investigate the diagnosis,treatment,and outcome of Mirizzi syndrome in patients undergoing laparoscopic cholecystectomy( LC). Methods A retrospective analysis was performed on the clinical data of 32 patients who underwent LC in the 451 Hospital of PLA from December 2006 to December 201...
Clinical application of selective intraoperative cholangiography in biliary system surgery
Wu ErBin, Zhang JinWei
2016, 32(7): 1357-1359. DOI: 10.3969/j.issn.1001-5256.2016.07.031
Abstract(2185) PDF (1502KB)(417) Cited By (4)
Abstract:
Objective To investigate the value of selective intraoperative cholangiography( IOC) in biliary system surgery. Methods A retrospective analysis was performed on the clinical data and follow- up data of 112 patients who were hospitalized in The First People's Hospital of Pingdingshan and underwent s...
Role of therapeutic endoscopic retrograde cholangiopancreatography in treatment of pancreaticobiliary diseases
Jiang ShengJun, Wang YongGuang, Li QiMei, Liu Ji, Tao LingYun, Jin Hui, Liu XiaoJing
2016, 32(7): 1360-1363. DOI: 10.3969/j.issn.1001-5256.2016.07.032
Abstract(2156) PDF (1517KB)(440) Cited By (12)
Abstract:
Objective To investigate the effect of therapeutic endoscopic retrograde cholangiopancreatography( ERCP) on liver function and treatment outcome in patients with pancreaticobiliary diseases. Methods A total of 397 patients with pancreaticobiliary diseases who underwent ERCP with an electronic duoden...
Value of serum carbohydrate antigens 19-9 and 24-2 in diagnosis of benign and malignant biliary tract diseases
Cui DaPeng, Zhang YingChun, Gao ShuQuan, Han Lei, Zhang YiJun, Zhao LiJuan, Liu ZhenXian, Yang He
2016, 32(7): 1364-1367. DOI: 10.3969/j.issn.1001-5256.2016.07.033
Abstract(2431) PDF (1521KB)(431) Cited By (4)
Abstract:
Objective To investigate the value of serum carbohydrate antigen 19- 9( CA19- 9) and carbohydrate antigen 24- 2( CA24-2) in the diagnosis of benign and malignant biliary tract diseases. Methods A total of 214 patients with biliary tract diseases who were hospitalized in Department of Gastroenterolog...
Original articles_Others
Influencing factors for the length of hospital stay in patients with drug-induced liver injury
Du ShuiXian, Lu LinLin, Xin YongNing, Liu Yang, Yuan Chen, Gu JiuLian, Xuan ShiYing
2016, 32(7): 1368-1372. DOI: 10.3969/j.issn.1001-5256.2016.07.034
Abstract(2225) PDF (1537KB)(476) Cited By (5)
Abstract:

Objective To investigate the influencing factors for the length of hospital stay in patients with drug- induced liver injury( DILI),and to guide clinical practice,reduce the pressure of hospitalization,and reduce the patients' economic burden. Methods The clinical data of the patients with DILI who ...

Risk factors for liver injury in patients with acquired immunodeficiency syndrome treated with nevirapine
Liu Pei, Gao ShiCheng
2016, 32(7): 1373-1377. DOI: 10.3969/j.issn.1001-5256.2016.07.035
Abstract(2132) PDF (1539KB)(446) Cited By (3)
Abstract:

Objective To investigate the risk factors for hypersensitivity- associated liver injury induced by the combined antiretroviral therapy( c- ART) including nevirapine( NVP) in patients with acquired immunodeficiency syndrome. Methods The clinical data and blood samples of 132 patients who received the...

Clinical features and risk factors for patients with liver failure complicated by invasive pulmonary aspergillosis
Xiao ErHui, Ning HuiBin, Kang Yi, Cao YongGe, Wei JunFeng, Shang Jia
2016, 32(7): 1378-1381. DOI: 10.3969/j.issn.1001-5256.2016.07.036
Abstract(2547) PDF (1519KB)(441) Cited By (12)
Abstract:

Objective To investigate the clinical features and risk factors for patients with liver failure complicated by invasive pulmonary aspergillosis( IPA),and to provide a reference for clinical diagnosis and treatment. Methods The clinical data of 477 patients with liver failure who were diagnosed and t...

Clinical features of HIV/AIDS patients with digestive diseases
Yin Fei, Zhou WeiHong
2016, 32(7): 1382-1387. DOI: 10.3969/j.issn.1001-5256.2016.07.037
Abstract(1945) PDF (1566KB)(433) Cited By (3)
Abstract:

Objective To analyze the clinical data of patients admitted with an initial diagnosis of digestive diseases who have human immunodeficiency virus( HIV) / acquired immune deficiency syndrome( AIDS),and to guide clinical diagnosis. Methods The clinical data of HIV / AIDS patients who were hospitalized...

Influence of extracellular signal-regulated kinase 1/2 pathway inhibitor PD98059 on proliferation and killing function of γδT cells cultured in vitro
Sun LeiQing, Xu Jing, Chen YongQiang, Zheng Lu, Lu: XiaoTing, Liu JunQuan, Chen FuXing, Zhou ZhongHai
2016, 32(7): 1388-1391. DOI: 10.3969/j.issn.1001-5256.2016.07.038
Abstract:

Objective To investigate the effect of extracellular signal- regulated kinase 1/2( ERK1/2) pathway inhibitor PD98059 on the proliferation and killing function of γδT cells cultured in vitro. Methods Mononuclear cells were separated from peripheral blood in healthy subjects and placed in RPMI 1640 co...

Case reports
HBV/HCV co-infection complicated by HBV-associated glomerulonephritis: a report of one case
Xue Liang
2016, 32(7): 1392-1393. DOI: 10.3969/j.issn.1001-5256.2016.07.039
Abstract:
One rare case of chronic active Epstein-Barr virus infection in adults
Jia ShengNan, Yang LanLan, Shao Xue, Liu SiQi, Jin ZhenJing
2016, 32(7): 1394-1395. DOI: 10.3969/j.issn.1001-5256.2016.07.040
Abstract(2438) PDF (1494KB)(488) Cited By (2)
Abstract:
Epithelioid hemangioendothelioma of the liver: a case report
Li Xu, Guo XiaoLin, Ji HuiFan, Li Xin, Gao PuJun
2016, 32(7): 1396-1397. DOI: 10.3969/j.issn.1001-5256.2016.07.041
Abstract(2331) PDF (1649KB)(481) Cited By (1)
Abstract:
Reviews
New immunotherapeutic strategies for chronic hepatitis B
Liu Shi, Tang ShanHong, Zhong XiaoZhu
2016, 32(7): 1398-1402. DOI: 10.3969/j.issn.1001-5256.2016.07.042
Abstract(2413) PDF (1775KB)(485) Cited By (5)
Abstract:
Chronic hepatitis B( CHB) is one of the most important infectious diseases around the world. Currently,interferon and nucleos( t) ide analogues are the main drugs for CHB and have good therapeutic efficacy,but the ultimate goal of eliminating hepatitis B virus( HBV) in human body has not been achiev...
Research advances in determination of hepatitis B core antibody level
Wang Wei, Zhao ZhaoXia, Li YuXiao, Rong Jun, Gao PengBin, Zheng HuanWei, Zhao CaiYan
2016, 32(7): 1403-1405. DOI: 10.3969/j.issn.1001-5256.2016.07.043
Abstract(1942) PDF (1738KB)(482) Cited By (4)
Abstract:
With the development and application of the double antigen sandwich method for quantification of hepatitis B core antibody( HBcAb) in recent years,there is increasing knowledge of the ability of HBcAb to reflect the body's anti- viral capability. This article introduces the commonly used measurement...
Association between hepatitis B virus pre-S/S gene variants and HBV-related liver diseases
Yao MingQi, Chen Jie, Zhang Jing
2016, 32(7): 1406-1408. DOI: 10.3969/j.issn.1001-5256.2016.07.044
Abstract:
The pre- S/S gene variants of hepatitis B virus( HBV) cause various pathological and clinical outcomes. Occult hepatitis B,fulminant hepatitis or liver failure,HBs Ag- and HBs Ab- positive HBV infection,and primary liver cancer are all associated with HBV pre- S/S gene variants,which are involved in...
Research advances in liver cirrhosis complicated by portal vein thrombosis
Wang WanQin, Wen MaoYao, Fan XiaoLi, Shen Yi, Yang XiaoXue, Yang Li
2016, 32(7): 1409-1412. DOI: 10.3969/j.issn.1001-5256.2016.07.045
Abstract(1561) PDF (1523KB)(453) Cited By (7)
Abstract:
Portal vein thrombosis( PVT) is a common complication of liver cirrhosis. This article reviews the research advances in liver cirrhosis complicated by PVT in recent years and points out that PVT is induced by the combined effect of various factors. Hemodynamic disorder is an important basis for the ...
Research advances in prevention and treatment of primary liver cancer with metabolic agents
Liu Yan, Ye Nan, Gong JianPing
2016, 32(7): 1413-1417. DOI: 10.3969/j.issn.1001-5256.2016.07.046
Abstract(2556) PDF (1592KB)(465) Cited By (9)
Abstract:
Recently,more and more studies have shown that the development and progression of primary liver cancer( hereinafter referred to as liver cancer) is closely associated with the metabolism in human body,and metabolic disturbance in human body increases the incidence and mortality of liver cancer. The ...
Application of tumor-associated antigens and their autoantibodies in early diagnosis of hepatocellular carcinoma
Wang Ting, Liu Mei, Dong Lei, Duan ZhongPing
2016, 32(7): 1418-1421. DOI: 10.3969/j.issn.1001-5256.2016.07.047
Abstract(2146) PDF (1527KB)(420) Cited By (1)
Abstract:
Early identification and diagnosis of hepatocellular carcinoma( HCC) is necessary for improving survival rates of HCC patients.Studies have shown that the abnormal proteins released by tumor cells,i. e.,the autoantibodies stimulated by tumor- associated antigens( TAAs),can be detected before a clini...
Role of tumor-associated macrophages in development and progression of primary liver cancer
Chen Wei, Zhou Yun, Gong JianPing
2016, 32(7): 1422-1424. DOI: 10.3969/j.issn.1001-5256.2016.07.048
Abstract(2308) PDF (1509KB)(458) Cited By (8)
Abstract:
The relationship between inflammatory response and tumor has gained great attention in recent years. Tumor- associated macrophages( TAMs) play an important role in tumor growth,proliferation,metabolism,and metastasis. Many studies have confirmed that most TAMs have an M2 phenotype and can promote tu...
Research advances in zebrafish as a model of liver cancer
Wang XinJuan
2016, 32(7): 1425-1428. DOI: 10.3969/j.issn.1001-5256.2016.07.049
Abstract(2749) PDF (1515KB)(518) Cited By (8)
Abstract:
The incidence rate of liver cancer tends to increase in recent years,and the molecular and pathogenic mechanisms of liver cancer should be further investigated to guarantee health. As an important model organism,zebrafish have highly conserved genes and grow fast.The early embryo of zebrafish is tra...
Research advances in sinusoidal obstruction syndrome
Li HaiNi, Zhang Min
2016, 32(7): 1429-1432. DOI: 10.3969/j.issn.1001-5256.2016.07.050
Abstract(2692) PDF (1526KB)(595) Cited By (19)
Abstract:
Sinusoidal obstruction syndrome( SOS) is a sinusoidal or small venous fibrous occlusive disease. This article reviews the research advances in the etiology,pathogenesis,clinical manifestations,auxiliary examinations,and treatment of SOS,and points out that the pathogenesis of SOS remains unknown and...
Research advances in differential diagnosis of benign and malignant ascites
Sun Juan, Niu ChunYan
2016, 32(7): 1433-1438. DOI: 10.3969/j.issn.1001-5256.2016.07.051
Abstract(3271) PDF (1553KB)(521) Cited By (9)
Abstract:
Differential diagnosis of benign and malignant ascites is of a great value in determining etiology,evaluating prognosis,and determining therapy regimens. There are many diagnostic methods for ascites,but up to now,no method can achieve high sensitivity and specificity and meet the requirements of cl...