2017 No. 1

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Editorial

Fluid therapy for acute pancreatitis: timing of resuscitation,type of fluid,and monitoring methods

Wu Dong, Qian JiaMing

2017, 33(1): 12-16. DOI: 10.3969/j.issn.1001-5256.2017.01.001

Abstract(639)

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Abstract:

Microcirculation disturbance and ischemia of the pancreas are important pathophysiological changes in the onset of acute pancreatitis,and organ hypoperfusion is a risk factor for poor prognosis. During the first 12 to 24 hours after admission,fluid resuscitation is the most important medical treatme...

The Chinese dream: hepatitis B-free generation

Fan Rong, Yin XueRu, Hou JinLin, Liu ZhiHua

2017, 33(1): 17-20. DOI: 10.3969/j.issn.1001-5256.2017.01.002

Abstract(473)

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Abstract:

In China,hepatitis B virus( HBV) infection remains a great threat to public health. Preventing the mother- to- child transmission( MTCT) of HBV is the main method to reduce the harm and disease burden caused by viral hepatitis in China. Recent studies have demonstrated that antiviral therapy with te...

Therapeutic guidelines

Definition and classification of chyle leak after pancreatic operation: a consensus statement by the International Study Group on Pancreatic Surgery in 2016

Gu GuangLiang, Yang GuiYuan, Qian ZhuYin

2017, 33(1): 21-24. DOI: 10.3969/j.issn.1001-5256.2017.01.003

Abstract(431)

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Abstract:

An excerpt of management of adult pancreatic injuries: a practice management guideline from the Eastern Association for the Surgery of Trauma (2016)

Xie ZhiBo, Zou CaiFeng, Fu DeLiang

2017, 33(1): 25-27. DOI: 10.3969/j.issn.1001-5256.2017.01.004

Abstract(2164)

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Abstract:

An excerpt of 2016 NCI guidelines for childhood liver cancer treatment (health professional version)

Peng Zhong, Qi XingShun, He ZhangXiu, Han Tao, Guo XiaoZhong

2017, 33(1): 28-31. DOI: 10.3969/j.issn.1001-5256.2017.01.005

Abstract(281)

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Discussions by experts

Timing and techniques of surgical intervention for acute pancreatitis: consensus and controversy

Li Fei

2017, 33(1): 32-35. DOI: 10.3969/j.issn.1001-5256.2017.01.006

Abstract(1970)

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Abstract:
Acute pancreatitis has uncertain and complicated conditions,and non- surgical treatment is mainly used during the early stage.However,as for the causes of acute pancreatitis in early stage,timely surgical intervention should be given to control some causes. This article also elaborates on the applic...

Early nutrition support therapy for patients with severe acute pancreatitis

Jing Xue, Tian ZiBin

2017, 33(1): 36-39. DOI: 10.3969/j.issn.1001-5256.2017.01.007

Abstract(3019)

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Abstract:
Nutrition support therapy plays an important role in the treatment of severe acute pancreatitis( SAP). This article reviews the hot topics and new ideas in nutrition support therapy for SAP in recent years. Damage of intestinal mucosal barrier plays an important role in the progression of pancreatit...

Association between pancreatitis and fatty liver disease

Gao Fan, Qi XingShun, Hou Yue, Guo XiaoZhong

2017, 33(1): 40-45. DOI: 10.3969/j.issn.1001-5256.2017.01.008

Abstract(3012)

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Abstract:
Pancreatitis is a common digestive disease with a high mortality rate. Clinical physicians often encounter patients with pancreatitis and fatty liver disease. This article investigates the association between pancreatitis and fatty liver disease from the aspects of the prevalence of fatty liver dise...

Current status of diagnosis and treatment of pancreatic encephalopathy

Zhang YongGuo, Guo XiaoZhong

2017, 33(1): 46-48. DOI: 10.3969/j.issn.1001-5256.2017.01.009

Abstract(2681)

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Abstract:
Pancreatic encephalopathy( PE) is a serious complication of pancreatitis,with difficulties in early diagnosis and poor prognosis.This article introduces the possible pathogenesis of PE involving pancreatin activation,cytokines,infection,water and electrolyte imbalance,and vitamin deficiency,summariz...

Application of needle- based confocal laser endomicroscopy in diagnosis of pancreatic cystic lesions

Zhang MingMing, Li YanQing

2017, 33(1): 49-52. DOI: 10.3969/j.issn.1001-5256.2017.01.010

Abstract(2458)

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Abstract:
Pancreatic cystic lesions( PCLs) have various pathological types,extremely different biological behaviors,and different prognosis. Current diagnosis of PCLs mainly depends on a comprehensive analysis of the patient's medical history,clinical manifestations,imaging examinations,serological examinatio...

Selection and therapeutic effect evaluation of chemotherapy regimens for pancreatic cancer

Zhuo Meng, Cui JiuJie, Wang LiWei

2017, 33(1): 53-56. DOI: 10.3969/j.issn.1001-5256.2017.01.011

Abstract(3496)

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Abstract:
Pancreatic cancer is a highly malignant tumor and its treatment is still a challenge. Recent studies have shown that medication plays an important role in preoperative and postoperative adjuvant therapy for locally advanced pancreatic cancer and is also a major therapeutic method for advanced pancre...

Developmental history of the extent of lymph node dissection in pancreatic cancer surgery

Gou ShanMiao, Wu HeShui

2017, 33(1): 57-60. DOI: 10.3969/j.issn.1001-5256.2017.01.012

Abstract(2959)

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Abstract:
Pancreatic cancer is one of the digestive malignant tumors with the worst prognosis and has an overall 5- year survival rate as low as 5%. Even though radical resection is performed,the 5- year survival rate is only about 20%. Recurrence and metastasis are the most important influencing factors for ...

Original articles_Viral hepatitis

Medical expenditure of hepatitis B virus infection and its impact factors analysis in Qidong,Jiangsu Province

Wang YuTing, Huang HuiYao, Qin HaiSong, Yao HongYu, Chen Song, Yu DongMei, Dai Min, Chen TaoYang, Qu ChunFeng, Shi JuFang

2017, 33(1): 61-66. DOI: 10.3969/j.issn.1001-5256.2017.01.013

Abstract(2442)

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Abstract:

Objective To quantify the medical expenditure per case of patients with hepatitis B virus- related diseases in Qidong,Jiangsu,China,and analyze its composition and related influencing factors. Methods Cluster sampling was used to select consecutive cases in The People's Hospital of Qidong and Qidong...

Expression of achaete-scute homologue 2 and its correlation with serum globulin in patients with chronic hepatitis C

Zhao JieRu, Fan Chao, Zheng XuYang, Qin Yuan, Zhang PeiXin, Li MengYuan, Wang YaNing, Zhang Ying, Hao ChunQiu, Jia ZhanSheng

2017, 33(1): 67-71. DOI: 10.3969/j.issn.1001-5256.2017.01.014

Abstract(2240)

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Abstract:

Objective To investigate the correlation between peripheral CD4+CXCR5+PD- 1+T cells and serum globulin in chronic hepatitis C( CHC) patients and health volunteers,and to clarify the role of the expression of achaete- scute homologue 2( Ascl2),the transcription factor in peripheral follicular helper ...

Original articles_Liver fibrosis and liver cirrhosis

A preliminary study of the changes in sex hormone levels in female patients with liver cirrhosis

Li Li, Li HongFang, Yi Wei, Zhuang QianYing, Hu YuHong, Jiang HongLi

2017, 33(1): 72-75. DOI: 10.3969/j.issn.1001-5256.2017.01.015

Abstract(2387)

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Abstract:

Objective To investigate the characteristics of the changes in sex hormone levels in female patients with liver cirrhosis. Methods A total of 30 female patients with liver cirrhosis who visited or were hospitalized in Beijing Ditan Hospital,Capital Medical University from September 2014 to June 2015...

Clinical effect of esophageal variceal ligation in treatment of esophageal variceal bleeding in patients with liver cirrhosis

Zhang DongXu, Luo ZiYi

2017, 33(1): 76-81. DOI: 10.3969/j.issn.1001-5256.2017.01.016

Abstract(2664)

PDF (1751KB)(451) Cited By (31)

Abstract:

Objective To investigate the clinical effect of endoscopic esophageal variceal ligation( EVL) in the treatment of esophageal variceal bleeding( EVB) in patients with liver cirrhosis. Methods A total of 84 liver cirrhosis patients with EVB who were admitted to The Third People's Hospital of Shenzhen,...

Original articles_Liver neoplasms

Correlation between drug-resistance gene mutations and hepatocellular carcinoma in patients with hepatitis B virus infection

Pang Ting, Xing HuiChun

2017, 33(1): 82-86. DOI: 10.3969/j.issn.1001-5256.2017.01.017

Abstract(2414)

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Abstract:

Objective To investigate the correlation between hepatitis B virus( HBV) drug- resistance gene mutations and hepatocellular carcinoma( HCC). Methods The clinical data of treatment- experienced patients,who underwent examination for HBV drug- resistance gene mutations in Beijing Ditan Hospital from J...

Clinical effect of ginger- partitioned moxibustion combined with transarterial chemoembolization in treatment of primary liver cancer with stagnation of liver qi and spleen deficiency

Zhu JiaYu, Xu Wang, Chen Chuang, Ou Jie, Mao SuFei, Mo XiaoLi, Lu DongLing

2017, 33(1): 87-90. DOI: 10.3969/j.issn.1001-5256.2017.01.018

Abstract(2469)

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Abstract:

Objective To investigate the clinical effect of ginger- partitioned moxibustion at Zusanli and Yongquan points combined with transarterial chemoembolization( TACE) in the treatment of primary liver cancer. Methods A total of 60 patients initially diagnosed with primary liver cancer with stagnation o...

Clinical effect of radiofrequency ablation in treatment of hepatic hemangioma

Sun LiBo, Zhao XiaoFei, Zhang HaiTao, Wu JuShan, Lin DongDong, Zang YunJin, Fu Zhi, Li Ning

2017, 33(1): 91-94. DOI: 10.3969/j.issn.1001-5256.2017.01.019

Abstract(2380)

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Abstract:

Objective To investigate the clinical effect and application experience of radiofrequency ablation in the treatment of hepatic hemangioma. Methods A retrospective analysis was performed for the clinical data of 34 patients with hepatic hemangioma who underwent radiofrequency ablation in Beijing You'...

Original articles_Biliary diseases

Risk factors for pyogenic cholangitis in patients with common bile duct stones

Wang ChunQiu, Ma YingCai, Zhu ZhiYong, Yuan Ling

2017, 33(1): 95-97. DOI: 10.3969/j.issn.1001-5256.2017.01.020

Abstract(2389)

PDF (1468KB)(452) Cited By (15)

Abstract:

Objectives To investigate the early risk factors for pyogenic cholangitis in patients with common bile duct stones. Methods The clinical data of patients with common bile duct stones within 3 days after admission,who visited Qinghai Provincial People' s Hospital from January 2013 to June 2015,were c...

Postoperative infection in laparoscopic cholecystectomy in treatment of acute cholecystitis complicated by choleperitonitis

Yang YaLin, Xu ZhiJie

2017, 33(1): 98-101. DOI: 10.3969/j.issn.1001-5256.2017.01.021

Abstract(2460)

PDF (1505KB)(449) Cited By (66)

Abstract:

Objective To investigate the influence of laparoscopic cholecystectomy( LC) versus open cholecystectomy( OC) on postoperative systemic infection and immune response in patients with acute cholecystitis complicated by choleperitonitis. Methods A prospective randomized controlled trial was performed f...

Clinical effect of anatomical hepatectomy in treatment of intrahepatic bile duct stones

Wang DianBei, Zhao LiJin, Tu Kui, Yu Qin

2017, 33(1): 102-105. DOI: 10.3969/j.issn.1001-5256.2017.01.022

Abstract(2534)

PDF (1475KB)(444) Cited By (22)

Abstract:

Objective To investigate the clinical effect of anatomical hepatectomy in the treatment of intrahepatic bile duct stones. Methods A retrospective analysis was performed for the clinical data of 117 patients with intrahepatic bile duct stones who underwent hepatectomy in The Affiliated Hospital of Zu...

Original articles_Pancreatic diseases

Clinical effect of early bowel-relaxing treatment and drainage in treatment of severe acute pancreatitis with intra-abdominal hypertension

Wang Qiang, Tang CaiXi, Feng Bin, Yang KaiQing, He MingLian, Zhao ZhiJian

2017, 33(1): 106-109. DOI: 10.3969/j.issn.1001-5256.2017.01.023

Abstract(2045)

PDF (1478KB)(403) Cited By (11)

Abstract:

Objective To investigate the clinical effect of early bowel- relaxing treatment and drainage in the treatment of severe acute pancreatitis( SAP). Methods A retrospective analysis was performed for the clinical data of 52 patients with SAP who were admitted to Department of Hepatopancreatobiliary Sur...

Clinical effect of ulinastatin in preventing pancreatitis after endoscopic retrograde cholangiopancreatography: a Meta-analysis

Li Lu, Wei HongCheng, Feng ShuFen

2017, 33(1): 110-115. DOI: 10.3969/j.issn.1001-5256.2017.01.024

Abstract(2287)

PDF (1779KB)(406) Cited By (5)

Abstract:

Objective To investigate the clinical effect of ulinastatin in preventing pancreatitis after endoscopic retrograde cholangiopancreatography( ERCP). Methods The Cochrane Library,Pub Med,EMBASE,CNKI,VIP,and Wanfang Data were searched for randomized controlled trials( RCTs) on ulinastatin for the preve...

Risk factors for pancreatic fistula after pancreaticoduodenectomy

Wang XiaoLong, Tu YanYuan, Wang Wei, Yuan ZuRong, Tang JianXiong, Tang WenHao, Wang WeiYi

2017, 33(1): 116-120. DOI: 10.3969/j.issn.1001-5256.2017.01.025

Abstract(2700)

PDF (238KB)(423) Cited By (34)

Abstract:

Objective To investigate the risk factors for pancreatic fistula after pancreaticoduodenectomy( PD),and to provide a reference for the prevention and treatment of pancreatic fistula after PD in clinical treatment. Methods A retrospective analysis was performed for the clinical data of 75 patients wh...

Safety of fast track surgery in pancreaticoduodenectomy: a Meta-analysis

Li WeiNan, Yang Gang, Li JingDong, Tang Tao, Li Qiang, Li Yong

2017, 33(1): 121-125. DOI: 10.3969/j.issn.1001-5256.2017.01.026

Abstract(2347)

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Abstract:

Objective To investigate the safety and clinical effect of fast track surgery in pancreaticoduodenectomy,one of the most complex surgeries in general surgery. Methods The Chinese and foreign databases were searched for articles on the application of fast tract surgery in pancreaticoduodenectomy publ...

Value of contrast- enhanced ultrasound in evaluating peripancreatic vascular invasion and resectability of pancreatic cancer

Liu Zhan, Tang ShaoShan

2017, 33(1): 126-129. DOI: 10.3969/j.issn.1001-5256.2017.01.027

Abstract(2423)

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Abstract:

Objective To investigate the value of preoperative contrast- enhanced ultrasound( CEUS) in evaluating peripancreatic vascular invasion and resectability of pancreatic cancer. Methods A retrospective analysis was performed for the clinical data of 25 patients with pancreatic cancer confirmed by surgi...

Expression of NEDD9 and its clinical significance in pancreatic cancer

Wu TieLong, Xue LiLi, Dai YuanYuan, Sheng YingYue, Wang WenYuan, Xue YuZheng

2017, 33(1): 130-132. DOI: 10.3969/j.issn.1001-5256.2017.01.028

Abstract(2293)

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Abstract:

Objective To investigate the expression of neural precursor cell- expressed,developmentally down- regulated 9( NEDD9) in pancreatic cancer tissues and adjacent tissues and its association with the progression and prognosis of pancreatic cancer. Methods A total of 98 patients with pancreatic cancer w...

Expression of cysteinyl leukotriene receptor-1 in pancreatic cancer tissue and its clinical significance

Meng Yan, Zhu Ying, Zhang YaQing, Zou LingYun, Zhang QiuNan

2017, 33(1): 133-136. DOI: 10.3969/j.issn.1001-5256.2017.01.029

Abstract(2559)

PDF (1476KB)(445) Cited By (5)

Abstract:

Objective To investigate the expression of cysteinyl leukotriene receptor- 1( Cys LTR- 1) in pancreatic cancer tissue and its association with clinical features and prognosis. Methods A total of 42 patients with pathologically confirmed pancreatic cancer who were admitted to Central Hospital of Hulu...

Original articles_Others

Clinical effect of Kezhi capsules in treatment of nonalcoholic steatohepatitis

Ning HuiMing, Ou Qiang, Huang Ling, Tang Qun

2017, 33(1): 137-140. DOI: 10.3969/j.issn.1001-5256.2017.01.030

Abstract(2467)

PDF (1475KB)(455) Cited By (24)

Abstract:

Objective To investigate the clinical effect and safety of Kezhi capsules in the treatment of nonalcoholic steatohepatitis( NASH). Methods A total of 100 patients with NASH who visited The Eighth People's Hospital of Shanghai from November 2013 to December 2015 were enrolled and randomly divided int...

Chronological changes in clinical features of autoimmune liver disease at initial diagnosis

Li YanNi, Zhou Lu, Zhang Jie, Deng BaoRu, Guo LiPing, Zhang Jun, Wang BangMao

2017, 33(1): 141-145. DOI: 10.3969/j.issn.1001-5256.2017.01.031

Abstract(2549)

PDF (1485KB)(483) Cited By (8)

Abstract:

Objective To investigate the chronological changes in the clinical features of autoimmune liver disease( AILD) at initial diagnosis,presence or absence of complications of liver cirrhosis at initial diagnosis,initial diagnostic methods,and results of liver biopsy,to summarize the chronological chang...

Clinical features of pure red cell aplasia associated with human parvovirus B19 infection after liver transplantation

Zhang DaLi, Zang Hong, Gao YinJie, Guo TongSheng, Zhou Xia, He Xi, Liu HongLing

2017, 33(1): 146-149. DOI: 10.3969/j.issn.1001-5256.2017.01.032

Abstract(2446)

PDF (1529KB)(452) Cited By (10)

Abstract:

Objective To investigate the clinical features of patients with pure red cell aplasia( PRCA) associated with human parvovirus B19( HPV B19) infection after liver transplantation. Methods The clinical data of 420 patients who underwent liver transplantation in 302 Hospital of PLA from July 2007 to Ju...

Clinical significance of measurement of T lymphocyte subsets before splenectomy in patients with primary immune thrombocytopenia

Li JianYun, Tu ChuanQing, He De, Wang DianWen, Huang Can, Zhang XuYan, Feng Chun

2017, 33(1): 150-154. DOI: 10.3969/j.issn.1001-5256.2017.01.033

Abstract(2673)

PDF (1757KB)(487) Cited By (14)

Abstract:

Objective To investigate the changes in lymphocyte subsets and natural killer( NK) cells before splenectomy in patients with primary immune thrombocytopenia( ITP) who have no response to corticosteroid therapy or experience recurrence after drug withdrawal,as well as their association with early ITP...

A family with hereditary hemochromatosis carrying HFE gene splice site mutation: a case report

Ning HuiBin, He Jia, Li JunLi, Liu JunPing, Xiao ErHui, Shang Jia

2017, 33(1): 155-159. DOI: 10.3969/j.issn.1001-5256.2017.01.034

Abstract(2941)

PDF (2259KB)(478) Cited By (2)

Abstract:

Objective To investigate a new type of HFE gene mutation in a family with hereditary hemochromatosis( HH). Methods The analysis of HFE gene was performed for one patient with a confirmed diagnosis of HH and five relatives. Blood genomic DNA was extracted and PCR multiplication was performed for the ...

Case reports

Immune tolerance after drug withdrawal in a patient with chronic hepatitis B receiving PEG- IFNα- 2a treatment

Yang CaiXia

2017, 33(1): 160-162. DOI: 10.3969/j.issn.1001-5256.2017.01.035

Abstract(1791)

PDF (1482KB)(415) Cited By (2)

Abstract:

Sarcomatoid hepatocellular carcinoma with spontaneous bleeding: a case report

Liu MingJiang, Wang FengJiao, Ye JunFeng, Qi WenLei, Wang GuangYi, Du XiaoHong

2017, 33(1): 163-164. DOI: 10.3969/j.issn.1001-5256.2017.01.036

Abstract(1911)

PDF (1578KB)(442) Cited By (1)

Abstract:

A case of hepatic paragonimiasis

Yu Qin, Zhao LiJin, Tu Kui, Wang DianBei, Wang Fang

2017, 33(1): 165-166. DOI: 10.3969/j.issn.1001-5256.2017.01.037

Abstract(1835)

PDF (501KB)(411) Cited By (3)

Abstract:

Cefoperazone/sulbactam sodium-induced severe coagulation disorder in treatment of moderately severe acute pancreatitis: a case report

Lou LiLi, Zhao Xu, Wang SiRui, Guo XiaoLin

2017, 33(1): 167-168. DOI: 10.3969/j.issn.1001-5256.2017.01.038

Abstract(2586)

PDF (1448KB)(524) Cited By (14)

Abstract:

A case of intraductal papillary mucinous neoplasm with cholangiocarcinoma

Li ZhaoXin, Ma WenCong, Zhang Ping

2017, 33(1): 169-170. DOI: 10.3969/j.issn.1001-5256.2017.01.039

Abstract(1978)

PDF (1799KB)(408) Cited By (2)

Abstract:

Reviews

Role of serum abnormal prothrombin protein induced by vitamin K absence or antagonist-Ⅱ in development and progression of hepatocellular carcinoma

Li JunLi, Shang Jia, Ning HuiBin, Guo EnEn, He Jia

2017, 33(1): 171-174. DOI: 10.3969/j.issn.1001-5256.2017.01.040

Abstract(2657)

PDF (1714KB)(475) Cited By (10)

Abstract:

Early diagnosis of hepatocellular carcinoma( HCC) using tumor markers is very important for long- term survival. This article elaborates on the value and high sensitivity and specificity of protein induced by vitamin K absence or antagonist- Ⅱ( PIVKA- Ⅱ) in the early diagnosis,prognostic evaluation,...

Role of tumor necrosis factor- alpha- induced protein 8-like 2 in development and progression of liver and gastrointestinal tumors

Kong Li, Jin Meng, Zhao SuXian

2017, 33(1): 175-179. DOI: 10.3969/j.issn.1001-5256.2017.01.041

Abstract(2157)

PDF (1484KB)(420) Cited By (5)

Abstract:

Liver and gastrointestinal tumors greatly threaten human health and have poor therapeutic outcomes and prognosis. Tumor necrosis factor- alpha- induced protein 8- like 2( TIPE2) can negatively regulate innate immunity and adaptive immunity and maintain immune homeostasis. Recent studies have found t...

Diagnosis strategies for intrahepatic cholangiocarcinoma

Su LiHong, Zhu XinYu, Zhang LiaoYun

2017, 33(1): 180-183. DOI: 10.3969/j.issn.1001-5256.2017.01.042

Abstract(2553)

PDF (1464KB)(440) Cited By (23)

Abstract:

Intrahepatic cholangiocarcinoma is an uncommon malignant tumor,and its incidence has been increasing in the recent 30 years.Since patients have no specific clinical manifestations in early stage,the diagnosis of this disease is often very difficult,with a low rate of radical resection in late stage ...

Research advances in pharmacological prevention of pancreatitis after endoscopic retrograde cholangiopancreatography

Wang Ai, Zhao LiJin

2017, 33(1): 184-187. DOI: 10.3969/j.issn.1001-5256.2017.01.043

Abstract(2119)

PDF (1477KB)(402) Cited By (4)

Abstract:

Endoscopic retrograde cholangiopancreatography( ERCP) has become an important method for the diagnosis and treatment of cholangio- pancreatic duct diseases. Post- ERCP pancreatitis( PEP) is the most common complication and its incidence has increased up to 40% in recent years. The prevention of PEP ...

Research advances in integrated traditional Chinese and Western medicine therapy for severe acute pancreatitis

Zhu MeiDong, Luo YunQuan

2017, 33(1): 188-193. DOI: 10.3969/j.issn.1001-5256.2017.01.044

Abstract(2247)

PDF (1494KB)(419) Cited By (68)

Abstract:

Severe acute pancreatitis( SAP) is a special type of acute pancreatitis,and misdiagnosis and mistreatment can easily cause serious complications,which makes it a tough disease in clinical practice. In recent years,integrated traditional Chinese and Western medicine therapy for SAP has been explored ...