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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 37 Issue 10
Oct.  2021
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Article Contents

Noninvasive diagnostic models for chronic hepatitis B liver fibrosis

DOI: 10.3969/j.issn.1001-5256.2021.10.034
Research funding:

The High-level Health Technicians-reserve Talents Project of Yunnan Province (H-2017071);

The Scientific Research Project for the Department of Education of Yunnan Province (2021J0239)

  • Received Date: 2021-02-23
  • Accepted Date: 2021-03-23
  • Published Date: 2021-10-20
  • Hepatitis B virus (HBV) infection is still a public problem that seriously threatens human health. Evaluation of liver fibrosis progression with an efficient noninvasive model is of great significance for condition assessment, disease management, and prognostic evaluation in patients with chronic HBV infection. This article reviews the noninvasive models commonly used in the diagnosis of liver fibrosis in recent years, summarizes the research background, methods, related studies, and advantages and disadvantages of these models, and analyzes the current research status and possible development trends of liver fibrosis assessment models. Recent studies have shown that although current models are not perfect for Chinese patients with chronic HBV infection as the main predisposing factor for liver fibrosis, the excellent performance of noninvasive models in liver fibrosis assessment provides a reference for the assessment of liver fibrosis in patients with chronic HBV infection and can replace liver biopsy to a certain extent.

     

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