|
[1]Han C, Bowen WC, Li G, et al.Cytosolic phospholipase A2alpha and peroxisome proliferator-activated receptor gamma signaling pathway counteracts transforming growth factor beta-mediated inhibition of primary and transformed hepatocyte growth[J].Hepatology, 2010, 52 (2) :644-655.
|
|
[2]de Gouville AC, Boullay V, Krysa G, et al.Inhibition of TGF-beta signaling by an ALK5 inhibitor protects rats from dimethylnitrosamine-induced liver fibrosis[J].Br J Pharmacol, 2005, 145 (2) :166-177.
|
|
[3] Michalopoulos GK.Liver regeneration[J].J Cell Physiol, 2007, 213 (2) :286-300.临床肝胆病杂志2011年第27卷第5期
|
|
[4]Nguyen LN, Furuya MH, Wolfraim LA, et al.Transforming growth factor-beta differentially regulates oval cell and hepatocyte proliferation[J].Hepatology, 2007, 45 (1) :31-41.
|
|
[5]Thenappan A, Li Y, Kitisin K, et al.Role of transforming growth factor beta signaling and expansion of progenitor cells in regenerating liver[J].Hepatology, 2010, 51 (4) :1373-1382.
|
|
[6]Zhong Z, Tsukada S, Rehman H, et al.Inhibition of transforming growth factor-beta/Smad signaling improves regeneration of small-for-size rat liver grafts[J].Liver Transpl, 2010, 16 (2) :181-190.
|
|
[7]Mayoral R, Valverde AM, Llorente Izquierdo C, et al.Impairment of transforming growth factor beta signaling in caveolin-1-deficient hepatocytes:role in liver regeneration[J].J Biol Chem, 2010, 285 (6) :3633-3642.
|
|
[8]Hughes RD, Evans LW.Activin A and follistatin in acute liver failure[J].Eur J Gastroenterol Hepatol, 2003, 15 (2) :127-131.
|
|
[9]Rodgarkia-Dara C, Vejda S, Erlach N, et al.The activin axis in liver biology and disease[J].Mutat Res, 2006, 613 (2-3) :123-137.
|
|
[10]Takamura K, Tsuchida K, Miyake H, et al.Activin and activin receptor expression changes in liver regeneration in rat[J].J Surg Res, 2005, 126 (1) :3-11.
|
|
[11]Lin SD, Kawakami T, Ushio A, et al.Ratio of circulating follistatin and activin A reflects the severity of acute liver injury and prognosis in patients with acute liver failure[J].J Gastroenterol Hepatol, 2006, 21 (2) :374-380.
|
|
[12]Soliman GM, Mohammed KA, Taha A, et al.The role ofplasma transforming growth factor beta-1 in the development of fibrosis in patient with HCV related steatohepatitis[J].J Egypt Soc Parasitol, 2010, 40 (3) :759-772.
|
|
[13]Wu XL, Zeng WZ, Jiang MD, et al.Effect of Oxymatrine on the TGFbeta-Smad signaling pathway in rats with CCl4-induced hepatic fibrosis[J].World J Gastroenterol, 2008, 14 (13) :2100-2105.
|
|
[14]Parsons CJ, Takashima M, Rippe RA.Molecular mechanisms of hepatic fibrogenesis[J].J Gastroenterol Hepatol, 2007, 22 (Suppl 1) :S79-84.
|
|
[15]Inagaki Y, Okazaki I.Emerging insights into Transforming growth factor beta Smad signal in hepatic fibrogenesis[J].Gut, 2007, 56 (2) :284-292.
|
|
[16]Cirrose hepáticaecélulas estreladas do figado.Liver cirrhosis and hepatic stellate cells[J].Acta Cirúrgica Brasileira, 2006, 21 (Suppl 1) :54-57.
|
|
[17]Date M, Matsuzaki K, MatsushitaM, et al.Differential regulation of activin A for hepatocyte growth and fibronectin synthesis in rat live injury[J].J Hepatol, 2000, 32 (2) :251-260.
|
|
[18]Chen YG, Lui HM, Lin SL, et al.Regulation of cell proliferation, apoptosis, and carcinogenesis by activin[J].Exp Biol Med (Maywood) , 2002, 227 (2) :75-87.
|
|
[19]Nishitsuji H, Kohara M, Kannagi M, et al.Effective suppression of human immunodeficiency virus type 1 through a combination of short-or long-hairpin RNAs targeting essential sequences for retroviral integration[J].J Virol, 2006, 80 (15) :7658-7666.
|
|
[20]Grimm D, Kay MA.RNAi and gene therapy:a mutual attraction[J].Hematology, 2007, (1) :473-481.
|
|
[21]Kreidl E, Oztürk D, Metzner T, et al.Activins and follistatins:Emerging roles in liver physiology and cancer[J].World J Hepatol, 2009, 1 (1) :17-27.
|
|
[22]Wanninger J, Neumeier M, Hellerbrand C, et al.Lipid accumulation impairs adiponectin-mediated induction of activin A by increasing TGFbeta in primary human hepatocytes[J].Biochim Biophys Acta, 2010.[Epub ahead of print]
|
|
[23]Romero-Gallo J, Sozmen EG, Chytil A, et al.Inactivation of TGF-beta signaling in hepatocytes results in an increased proliferative response after partial hepatectomy[J].Oncogene, 2005, 24 (18) :3028-3041.
|
|
[24]Takabe K, Wang L, Leal AM, et al.Adenovirus-mediated overexpression of follistatin enlarges intact liver of adult rats[J].Hepatology, 2003, 38:1107-1115.
|
|
[25]Katja B, Stephan H, Eliza W, et al.Anti-TGF-strategies for the treatment of chronic liver disease[J].Alcohol Clin Exp Res, 2005, 29 (11) :121S-131S.
|
|
[26]Patella S, Phillips DJ, Tchongue J, et al.Follistatin attenuates early liver fibrosis:effects on hepatic stellate cell activation and hepatocyte apoptosis[J].Am J Physiol Gastrointest Liver Physiol, 2006, 290 (1) :G137-144.
|
|
[27]Du SS, Qiang M, Zeng ZC, et al.Radiation-induced liver fibrosis is mitigated by gene therapy inhibiting transforming growth factor-βsignaling in the rat[J].Int J Radiat Oncol Biol Phys, 2010, 78 (5) :1513-1523.
|
|
[28]Zhou J, Zhong DW, Wang QW, et al.Paclitaxel ameliorates fibrosis in hepatic stellate cells via inhibition of TGF-beta/Smad activity[J].World J Gastroenterol, 2010, 16 (26) :3330-3334.
|
|
[29]Sharp PA.RNA interference-2001[J].Genes Dev, 2001, 15 (5) :485-490.
|
|
[30]Miest T, Saenz D, Meehan A, et al.Intensive RNAi with lentiviral vectors in mammalian cells[J].Methods, 2009, 47 (4) :298-303.
|
|
[31]Kusov Y, Kanda T, Palmenberg A, et al.Silencing of hepatitis A virus infection by small interfering RNAs[J].J Virol, 2006, 80 (11) :5599-5610.
|
DownLoad: